Imperial College London
Alternate

Dr Tini Garske

Faculty of Medicine, School of Public Health

Senior Lecturer
 
 
 
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Contact

 

t.garske Website

 
 
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Location

 

410School of Public HealthWhite City Campus

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Summary

 

Publications

Citation

BibTex format

@article{The:2018:10.1016/S0140-6736(18)31387-4,
author = {The, Ebola Outbreak Epidemiology Team and Bhatia, S and Cori, A and Donnelly, CA and Dorigatti, I and Ferguson, NM and Fitzjohn, RG and Forna, A and Garske, T and Gaythorpe, KAM and Imai, N and Nouvellet, P},
doi = {10.1016/S0140-6736(18)31387-4},
journal = {The Lancet},
pages = {213--221},
title = {Outbreak of Ebola virus disease in the Democratic Republic of the Congo, April–May, 2018: an epidemiological study},
url = {http://dx.doi.org/10.1016/S0140-6736(18)31387-4},
volume = {392},
year = {2018}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - BackgroundOn May 8, 2018, the Government of the Democratic Republic of the Congo reported an outbreak of Ebola virus disease in Équateur Province in the northwest of the country. The remoteness of most affected communities and the involvement of an urban centre connected to the capital city and neighbouring countries makes this outbreak the most complex and high risk ever experienced by the Democratic Republic of the Congo. We provide early epidemiological information arising from the ongoing investigation of this outbreak.MethodsWe classified cases as suspected, probable, or confirmed using national case definitions of the Democratic Republic of the Congo Ministère de la Santé Publique. We investigated all cases to obtain demographic characteristics, determine possible exposures, describe signs and symptoms, and identify contacts to be followed up for 21 days. We also estimated the reproduction number and projected number of cases for the 4-week period from May 25, to June 21, 2018.FindingsAs of May 30, 2018, 50 cases (37 confirmed, 13 probable) of Zaire ebolavirus were reported in the Democratic Republic of the Congo. 21 (42%) were reported in Bikoro, 25 (50%) in Iboko, and four (8%) in Wangata health zones. Wangata is part of Mbandaka, the urban capital of Équateur Province, which is connected to major national and international transport routes. By May 30, 2018, 25 deaths from Ebola virus disease had been reported, with a case fatality ratio of 56% (95% CI 39–72) after adjustment for censoring. This case fatality ratio is consistent with estimates for the 2014–16 west African Ebola virus disease epidemic (p=0·427). The median age of people with confirmed or probable infection was 40 years (range 8–80) and 30 (60%) were male. The most commonly reported signs and symptoms in people with confirmed or probable Ebola virus disease were fever (40 [95%] of 42 cases), intense general fatigue (37 [90%] of 41 cases), an
AU  - The,Ebola Outbreak Epidemiology Team
AU  - Bhatia,S
AU  - Cori,A
AU  - Donnelly,CA
AU  - Dorigatti,I
AU  - Ferguson,NM
AU  - Fitzjohn,RG
AU  - Forna,A
AU  - Garske,T
AU  - Gaythorpe,KAM
AU  - Imai,N
AU  - Nouvellet,P
DO  - 10.1016/S0140-6736(18)31387-4
EP  - 221
PY  - 2018///
SN  - 0140-6736
SP  - 213
TI  - Outbreak of Ebola virus disease in the Democratic Republic of the Congo, April–May, 2018: an epidemiological study
T2  - The Lancet
UR  - http://dx.doi.org/10.1016/S0140-6736(18)31387-4
UR  - http://hdl.handle.net/10044/1/61467
VL  - 392
ER  -
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