Imperial College London


Faculty of MedicineNational Heart & Lung Institute

CRN Assistant Cluster Lead & Gene Therapy Programme Manager



+44 (0)20 7594 7932t.higgins




172Emmanuel Kaye BuildingRoyal Brompton Campus








Mrs Tracy Harman nee Higgins is currently the Respiratory Research Strategy Manager for Royal Brompton & Harefield NHS Foundation Trust, and Project Manager for the UK Cystic Fibrosis Gene Therapy Consortium (Consortium).

Tracy trained as an Administration Manager, joining Imperial College in 2000 as the Laboratory Manager for the Gene Therapy Group, becoming the Consortium's Project Manager in 2006. From 2008-2017 the Royal Brompton and Harefield NHS Foundation Trust and Imperial College held BRU status for their programme and Tracy was the Respiratory BRU Manager for that period, taking on the Respiratory Research Strategy Manager role in 2017.

Tracy has experience in extensive financial management and contracting across numerous stakeholders, setting up and overseeing core facilities, running internal funding competitions, coordinating multi-centre grant submissions, linking NIHR infrastructure nationwide and keeping the patient at the centre of research initiatives.  She was the first Chair of the NIHR National BRC/U Managers Working Group, the aim of which was to bring together managers from the BRCs and BRUs to identify common challenges and initiate work packages to deliver solutions for those challenges, and also Chaired the NIHR National BRC/U Patient and Public Involvement /Engagement Group.

Current interests include developing research projects into programmes that are transformational to the wider NHS.



Alton EW, Beekman JM, Boyd AC, et al., 2016, Preparation for a first-in-man lentivirus trial in patients with cystic fibrosis, Thorax, Vol:72, ISSN:0040-6376, Pages:137-147

Alton EWFW, Boyd AC, Davies JC, et al., 2016, Genetic Medicines for CF: Hype versus Reality, Pediatric Pulmonology, Vol:51, ISSN:8755-6863, Pages:S5-S17

Griesenbach U, Alton EWFW, Boyd AC, et al., 2015, A Phase I/IIa safety and efficacy study of nebulized liposome-mediated gene therapy for cystic fibrosis supports a multidose trial, American Journal of Respiratory and Critical Care Medicine, Vol:192, ISSN:1535-4970, Pages:1389-1392

Alton EWFW, Armstrong DK, Ashby D, 2015, Repeated nebulisation of non-viral CFTR gene therapy in patients with cystic fi brosis: a randomised, double-blind, placebo-controlled, phase 2b trial (vol 3, pg 684, 2015), Lancet Respiratory Medicine, Vol:3, ISSN:2213-2600, Pages:684-691

Alton E, Griesenbach U, Davies JC, et al., A randomised, double-blind, placebo-controlled trial of repeated nebulisation of non-viral CFTR gene therapy in patients with cystic fibrosis, Lancet Respiratory Medicine, ISSN:2213-2619

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