Imperial College London
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Dr Taylor Lyons

Faculty of Medicine, Department of Brain Sciences

Honorary Research Associate
 
 
 
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Contact

 

t.lyons15

 
 
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Location

 

Burlington DanesHammersmith Campus

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Summary

 

Publications

Citation

BibTex format

@article{Zeifman:2023:10.1038/s41598-023-28111-3,
author = {Zeifman, R and Spriggs, M and Kettner, H and Lyons, T and Rosas, F and Mediano, P and Erritzoe, D and Carhart-Harris, R},
doi = {10.1038/s41598-023-28111-3},
journal = {Scientific Reports},
title = {From Relaxed Beliefs Under Psychedelics (REBUS) to Revised Beliefs After Psychedelics (REBAS)},
url = {http://dx.doi.org/10.1038/s41598-023-28111-3},
year = {2023}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Objectives: This was a cross sectional study aimed at describing chest x-ray findings among children hospitalised with clinically diagnosed severe pneumonia and hypoxaemia (SpO2<92%) in three tertiary facilities in Uganda.Methods: We studied chest x-rays of 375 children aged 28 days to 12 years enrolled into the Children’s Oxygen Administration Strategies Trial (COAST)(ISRCTN15622505). Radiologists blinded to the clinical findings reported chest x-rays using the standardized World Health Organization methodology for paediatric chest Xray reporting. We summarised clinical data and chest x-ray findings using descriptive statistics. Chi-square and proportion tests were used to compare proportions and quantile regression compared medians. Results: We found 172, (45.8%) children had radiological pneumonia, 136 (36.3%) normal chest radiographs while 123 (32.8%) non-pneumonia findings, the major one being cardiovascular abnormalities,106 (28.3%); 56 (14.9%) chest radiographs had both pneumonia and other abnormalities. There was no difference in the prevalence of radiological pneumonia, cardiovascular abnormalities, and mortality between the group with severe hypoxaemia (SpO2<80%) and that with mild hypoxaemia (SpO280 to <92%), (95% CI: -13.2,7.1, -6.1,15.9) and -37.2, 20.4) respectively. Conclusion: This study highlights a relatively high prevalence of cardiovascular abnormalities in children who fulfill the WHO clinical criteria for severe pneumonia and have hypoxaemia. We recommend that chest x-ray examinations be routinely done for all children in this population because information concerning cardiovascular and respiratory systems can be obtained in one sitting and guide management better. We hope that these findings can prompt discussions into refining the clinical criteria used to classify and manage pneumonia in children in limited resource settings.
AU  - Zeifman,R
AU  - Spriggs,M
AU  - Kettner,H
AU  - Lyons,T
AU  - Rosas,F
AU  - Mediano,P
AU  - Erritzoe,D
AU  - Carhart-Harris,R
DO  - 10.1038/s41598-023-28111-3
PY  - 2023///
SN  - 2045-2322
TI  - From Relaxed Beliefs Under Psychedelics (REBUS) to Revised Beliefs After Psychedelics (REBAS)
T2  - Scientific Reports
UR  - http://dx.doi.org/10.1038/s41598-023-28111-3
UR  - http://hdl.handle.net/10044/1/102760
ER  -
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