Tony Magee is Professor of Membrane Biology at the National Heart and Lung Institute, Imperial College London, and Head of the Section of Molecular Medicine.
Professor Magee trained in biochemistry and protein chemistry and began work on lipid modification of proteins as a post-doc in 1980. He continued to work in this field as an independent investigator at the MRC's NIMR (Mill Hill, 1983-2001) and Imperial College London (2001-present).
Professor Magee is an established leader in the field of protein lipidation and has been invited to speak at many international conferences and organise several colloquia and conferences. He has made major contributions in protein prenylation (co-discovering the prenylation of Ras proteins), protein acylation (of Ras proteins and Src family kinases) and lipid rafts (identifying a key role in T cell receptor signaling).
His current interests are in the enzymes catalyzing acylation of secreted proteins (e.g. Hedgehog proteins) and their role in cancer, in the functional role of protein acylation e.g. in signalling, and in novel applications of advanced light microscopy imaging.
Professor Magee is the academic lead for the Facility for Imaging by Light Microscopy (FILM), a multiuser facility in the Sir Alexander Fleming Building at South Kensington and ICTEM at Hammersmith campuses, currently with 12 microscopes (confocals, multiphotons, widefields, TIRF, superresolution, high content) providing access to state-of-the-art fluorescence microscopy. FILM has a highly experienced manager (Dr. A. Bruckbauer) and two support staff.
Professor Magee currently holds MRC and Wellcome Trust grants. He is also the Director of Postgraduate Studies for the NHLI and a Deputy Director of the Imperial College Graduate School.