Imperial College London
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Dr Tarun K Mittal MD, FRCR, MSc, FSCCT

Faculty of Medicine, National Heart & Lung Institute

Honorary Clinical Senior Lecturer
 
 
 
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Contact

 

+44 (0)1895 828 609t.mittal

 
 
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Location

 

Dept of Medical ImagingHarefield HospitalHarefield Hospital

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Summary

 

Publications

Citation

BibTex format

@article{Rogers:2018:10.1186/s40814-018-0363-8,
author = {Rogers, P and Al-Aidrous, S and Banya, W and Haley, SR and Mittal, T and Kabir, T and Panoulas, V and Raja, S and Bhudia, S and Probert, H and Prendergast, C and Spence, MS and Davies, S and Moat, N and Taylor, RS and Dalby, M},
doi = {10.1186/s40814-018-0363-8},
journal = {Pilot Feasibility Stud},
title = {Cardiac rehabilitation to improve health-related quality of life following trans-catheter aortic valve implantation: a randomised controlled feasibility study: RECOVER-TAVI Pilot, ORCA 4, For the Optimal Restoration of Cardiac Activity Group.},
url = {http://dx.doi.org/10.1186/s40814-018-0363-8},
volume = {4},
year = {2018}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - OBJECTIVES: Transcatheter aortic valve implantation (TAVI) is often undertaken in the oldest frailest cohort of patients undergoing cardiac interventions. We plan to investigate the potential benefit of cardiac rehabilitation (CR) in this vulnerable population. DESIGN: We undertook a pilot randomised trial of CR following TAVI to inform the feasibility and design of a future randomised clinical trial (RCT). PARTICIPANTS: We screened patients undergoing TAVI at a single institution between June 2016 and February 2017. INTERVENTIONS: Participants were randomised post-TAVI to standard of care (control group) or standard of care plus exercise-based CR (intervention group). OUTCOMES: We assessed recruitment and attrition rates, uptake of CR, and explored changes in 6-min walk test, Nottingham Activities of Daily Living, Fried and Edmonton Frailty scores and Hospital Anxiety and Depression Score, from baseline (30 days post TAVI) to 3 and 6 months post randomisation. We also undertook a parallel study to assess the use of the Kansas City Cardiomyopathy Questionnaire (KCCQ) in the post-TAVI population. RESULTS: Of 82 patients screened, 52 met the inclusion criteria and 27 were recruited (3 patients/month). In the intervention group, 10/13 (77%) completed the prescribed course of 6 sessions of CR (mean number of sessions attended 7.5, SD 4.25) over 6 weeks. At 6 months, all participants were retained for follow-up. There was apparent improvement in outcome scores at 3 and 6 months in control and CR groups. There were no recorded adverse events associated with the intervention of CR. The KCCQ was well accepted in 38 post-TAVI patients: mean summary score 72.6 (SD 22.6). CONCLUSIONS: We have demonstrated the feasibility of recruiting post-TAVI patients into a randomised trial of CR. We will use the findings of this pilot trial to design a fully powered multicentre RCT to inform the provision of CR and support guideline development to optimise health-r
AU  - Rogers,P
AU  - Al-Aidrous,S
AU  - Banya,W
AU  - Haley,SR
AU  - Mittal,T
AU  - Kabir,T
AU  - Panoulas,V
AU  - Raja,S
AU  - Bhudia,S
AU  - Probert,H
AU  - Prendergast,C
AU  - Spence,MS
AU  - Davies,S
AU  - Moat,N
AU  - Taylor,RS
AU  - Dalby,M
DO  - 10.1186/s40814-018-0363-8
PY  - 2018///
SN  - 2055-5784
TI  - Cardiac rehabilitation to improve health-related quality of life following trans-catheter aortic valve implantation: a randomised controlled feasibility study: RECOVER-TAVI Pilot, ORCA 4, For the Optimal Restoration of Cardiac Activity Group.
T2  - Pilot Feasibility Stud
UR  - http://dx.doi.org/10.1186/s40814-018-0363-8
UR  - https://www.ncbi.nlm.nih.gov/pubmed/30564436
VL  - 4
ER  -
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