Imperial College London


Faculty of Natural SciencesDepartment of Life Sciences

Honorary Senior Lecturer







Mrs Lucy Collyns +44 (0)20 7594 5395




Sir Alexander Fleming BuildingSouth Kensington Campus





I am a molecular biologist trying to manipulate the biology of the mosquitoes in ways that can interfere with their ability to transmit disease. I work mostly on the mosquito Anopheles gambiae, the main vector of the most severe form of human malaria in Africa. I am applying this work in the fields of genetic control, such as gene drive, and in understanding the genetics of insecticide resistance.

Since January 2019 I have taken up a position at group leader at the Liverpool School of Tropical Medicine but I will continue to hold an honorary appointment at Imperial to maintain some of my research and teaching interests there. 

Selected Publications

Journal Articles

Bernardini F, Kriezis A, Galizi R, et al., 2019, Introgression of a synthetic sex ratio distortion system from Anopheles gambiae into Anopheles arabiensis, Scientific Reports, Vol:9, ISSN:2045-2322

Kyrou K, Hammond AM, Galizi R, et al., 2018, A CRISPR-Cas9 gene drive targeting doublesex causes complete population suppression in caged Anopheles gambiae mosquitoes, Nature Biotechnology, Vol:36, ISSN:1087-0156, Pages:1062-1066

Hammond AM, Kyrou K, Bruttini M, et al., 2017, The creation and selection of mutations resistant to a gene drive over multiple generations in the malaria mosquito., PLOS Genetics, Vol:13, ISSN:1553-7390

Bernardini F, Galizi R, Wunderlich M, et al., 2017, Cross-Species Y Chromosome Function Between Malaria Vectors of the Anopheles gambiae Species Complex., Genetics, ISSN:0016-6731

Papa F, Windbichler N, Waterhouse RM, et al., 2017, Rapid evolution of female-biased genes among four species of Anopheles malaria mosquitoes, Genome Research, Vol:27, ISSN:1088-9051, Pages:1536-1548

Beaghton A, Hammond A, Nolan T, et al., 2017, Requirements for Driving Antipathogen Effector Genes into Populations of Disease Vectors by Homing, Genetics, Vol:205, Pages:1587-1596

Galizi R, Hammond A, Kyrou K, et al., 2016, A CRISPR-Cas9 sex-ratio distortion system for genetic control., Scientific Reports, Vol:6, ISSN:2045-2322

Nolan T, Crisanti A, 2016, DRIVING OUT MALARIA, Scientist, Vol:31, Pages:24-31

Hammond A, Galizi R, Kyrou K, et al., 2015, A CRISPR-Cas9 gene drive system-targeting female reproduction in the malaria mosquito vector Anopheles gambiae, Nature Biotechnology, Vol:34, ISSN:1087-0156, Pages:78-83

Neafsey DE, Waterhouse RM, Abai MR, et al., 2015, Highly evolvable malaria vectors: The genomes of 16 Anopheles mosquitoes, Science, Vol:347

Volohonsky G, Terenzi O, Soichot J, et al., 2015, Tools for Anopheles gambiae Transgenesis, G3-genes Genomes Genetics, Vol:5, Pages:1151-1163

Fuchs S, Behrends V, Bundy JG, et al., 2014, Phenylalanine Metabolism Regulates Reproduction and Parasite Melanization in the Malaria Mosquito, Plos One, Vol:9

Fuchs S, Rende E, Crisanti A, et al., 2014, Disruption of aminergic signalling reveals novel compounds with distinct inhibitory effects on mosquito reproduction, locomotor function and survival., Scientific Reports, Vol:4, Pages:srep05526-srep05526

Baker DA, Nolan T, Fischer B, et al., 2011, A comprehensive gene expression atlas of sex- and tissue-specificity in the malaria vector, Anopheles gambiae, BMC Genomics, Vol:12, ISSN:1471-2164

Catteruccia F, Nolan T, Loukeris TG, et al., 2000, Stable germline transformation of the malaria mosquito Anopheles stephensi, Nature, Vol:405, Pages:959-962

More Publications