Publications
144 results found
Antoniou S, Goddard L, Pettitt C, et al., 2013, DOES FIBRE REDUCE THE RISK OF CLOSTRIDIUM DIFFICILE DIARRHOEA IN NASOGASTRIC FED PATIENTS?, Annual General Meeting of the British-Society-of-Gastroenterology, Publisher: BMJ PUBLISHING GROUP, Pages: A208-A209, ISSN: 0017-5749
Farne HA, Martin NK, Main J, et al., 2013, C-reactive protein is a useful predictor of metronidazole treatment failure in mild-to-moderate <i>Clostridium difficile</i> infection, EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, Vol: 25, Pages: 33-36, ISSN: 0954-691X
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- Citations: 5
Williams HRT, Willsmore JD, Cox IJ, et al., 2012, Serum Metabolic Profiling in Inflammatory Bowel Disease, DIGESTIVE DISEASES AND SCIENCES, Vol: 57, Pages: 2157-2165, ISSN: 0163-2116
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- Citations: 72
Russo E, Petts G, Lloyd T, et al., 2012, THE EXPRESSION OF INTERLEUKIN 2 RECEPTOR IN INTESTINAL RESECTION SPECIMENS FROM PATIENTS WITH CROHN'S DISEASE AS ASSESSED BY IMMUNOHISTOCHEMISTRY, GUT, Vol: 61, Pages: A179-A179, ISSN: 0017-5749
Nolan JD, Johnston I, Dew T, et al., 2012, REDUCED CIRCULATING FGF19 LEVELS ARE ASSOCIATED WITH SYMPTOMS OF DIARRHOEA IN CROHN'S DISEASE, GUT, Vol: 61, Pages: A34-A35, ISSN: 0017-5749
Nayagam S, Selvapatt N, Auguste JL, et al., 2012, QUALITY OF COLONOSCOPIC PROCEDURES AMONG INDEPENDENTLY PRACTISING GASTROENTEROLOGY TRAINEES IN A NW LONDON COHORT: ARE THEY REACHING NATIONAL STANDARDS?, GUT, Vol: 61, Pages: A59-A60, ISSN: 0017-5749
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- Citations: 1
Russo E, Hicks L, Hoare J, et al., 2012, COLONOSCOPY IN PATIENTS PRESENTING WITH MELAENA AND A NORMAL UPPER GASTROINTESTINAL ENDOSCOPY: A RETROSPECTIVE REVIEW FROM A SINGLE UK CENTRE, GUT, Vol: 61, Pages: A163-A163, ISSN: 0017-5749
Greaves RAL, Wilkinson LF, Orchard T, 2012, ACCESSING INFORMATION ON IBD: A SURVEY OF SOURCES AND RELIABILITY OF INTERNET RESOURCES, GUT, Vol: 61, Pages: A396-A396, ISSN: 0017-5749
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- Citations: 3
Orchard TR, 2012, Management of arthritis in patients with inflammatory bowel disease., Gastroenterol Hepatol (N Y), Vol: 8, Pages: 327-329, ISSN: 1554-7914
Travis SPL, Higgins PDR, Orchard T, et al., 2011, Review article: defining remission in ulcerative colitis, ALIMENTARY PHARMACOLOGY & THERAPEUTICS, Vol: 34, Pages: 113-124, ISSN: 0269-2813
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- Citations: 131
Walker DG, Williams HRT, Kane SP, et al., 2011, Differences in Inflammatory Bowel Disease Phenotype between South Asians and Northern Europeans Living in North West London, UK, AMERICAN JOURNAL OF GASTROENTEROLOGY, Vol: 106, Pages: 1281-1289, ISSN: 0002-9270
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- Citations: 51
Mills S, von Roon AC, Tekkis PP, et al., 2011, Crohn disease., Am Fam Physician, Vol: 83, Pages: 1479-1481
Mills S, von Roon AC, Tekkis PP, et al., 2011, Crohn Disease, AMERICAN FAMILY PHYSICIAN, Vol: 83, Pages: 1479-1481, ISSN: 0002-838X
Orchard TR, van der Geest SAP, Travis SPL, 2011, Randomised clinical trial: early assessment after 2 weeks of high-dose mesalazine for moderately active ulcerative colitis - new light on a familiar question, ALIMENTARY PHARMACOLOGY & THERAPEUTICS, Vol: 33, Pages: 1028-1035, ISSN: 0269-2813
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- Citations: 23
Mowat C, Cole A, Windsor A, et al., 2011, Guidelines for the management of inflammatory bowel disease in adults., Gut, Vol: 60, Pages: 571-607
The management of inflammatory bowel disease represents a key component of clinical practice for members of the British Society of Gastroenterology (BSG). There has been considerable progress in management strategies affecting all aspects of clinical care since the publication of previous BSG guidelines in 2004, necessitating the present revision. Key components of the present document worthy of attention as having been subject to re-assessment, and revision, and having direct impact on practice include: The data generated by the nationwide audits of inflammatory bowel disease (IBD) management in the UK in 2006, and 2008. The publication of 'Quality Care: service standards for the healthcare of people with IBD' in 2009. The introduction of the Montreal classification for Crohn's disease and ulcerative colitis. The revision of recommendations for the use of immunosuppressive therapy. The detailed analysis, guidelines and recommendations for the safe and appropriate use of biological therapies in Crohn's disease and ulcerative colitis. The reassessment of the role of surgery in disease management, with emphasis on the importance of multi-disciplinary decision-making in complex cases. The availablity of new data on the role of reconstructive surgery in ulcerative colitis. The cross-referencing to revised guidelines for colonoscopic surveillance, for the management of metabolic bone disease, and for the care of children with inflammatory bowel disease. Use of the BSG discussion forum available on the BSG website to enable ongoing feedback on the published document http://www.bsg.org.uk/forum (accessed Oct 2010). The present document is intended primarily for the use of clinicians in the United Kingdom, and serves to replace the previous BSG guidelines in IBD, while complementing recent consensus statements published by the European Crohn's and Colitis Organisation (ECCO) https://www.ecco-ibd.eu/index.php (accessed Oct 2010).
Mills SC, von Roon AC, Tekkis PP, et al., 2011, Crohn's disease., BMJ Clin Evid, Vol: 2011
INTRODUCTION: Crohn's disease is a chronic condition of the gastrointestinal tract. It is characterised by transmural, granulomatous inflammation that occurs in a discontinuous pattern, with a tendency to form fistulae. The cause is unknown but may depend on interactions between genetic predisposition, environmental triggers, and mucosal immunity. METHODS AND OUTCOMES: We conducted a systematic review and aimed to answer the following clinical questions: What are the effects of medical treatments to induce remission in adults with Crohn's disease? What are the effects of surgical interventions to induce and maintain remission in adults with small-bowel Crohn's disease? What are the effects of surgical interventions to induce remission in adults with colonic Crohn's disease? What are the effects of medical interventions to maintain remission in adults with Crohn's disease; and to maintain remission following surgery? What are the effects of lifestyle interventions to maintain remission in adults with Crohn's disease? We searched: Medline, Embase, The Cochrane Library, and other important databases up to December 2009 (Clinical Evidence reviews are updated periodically, please check our website for the most up-to-date version of this review). We included harms alerts from relevant organisations such as the US Food and Drug Administration (FDA) and the UK Medicines and Healthcare products Regulatory Agency (MHRA). RESULTS: We found 93 systematic reviews, RCTs, or observational studies that met our inclusion criteria. CONCLUSIONS: In this systematic review we present information relating to the effectiveness and safety of the following interventions: aminosalicylates, antibiotics, azathioprine/mercaptopurine, ciclosporin, corticosteroids (oral), enteral nutrition, fish oil, infliximab, methotrexate, probiotics, resection, segmental colectomy, smoking cessation, and strictureplasty.
Walker DG, Bancil AS, Williams HR, et al., 2011, HOW HELPFUL ARE SEROLOGICAL MARKERS IN DIFFERENTIATING CROHN'S DISEASE FROM ULCERATIVE COLITIS IN INDIAN ASIAN INFLAMMATORY BOWEL DISEASE PATIENTS?, Annual Meeting on British-Society-of-Gasenterology, Publisher: B M J PUBLISHING GROUP, ISSN: 0017-5749
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- Citations: 2
Walker DG, Walker JN, Orchard TR, 2011, GASTROENTEROLOGY TRAINEES' VIEWS ON EDUCATIONAL SUPERVISORS: DO THEY FULFIL THEIR ROLE?, Annual Meeting on British-Society-of-Gasenterology, Publisher: B M J PUBLISHING GROUP, ISSN: 0017-5749
Davies MB, Cobbold JFL, Walker DG, et al., 2011, THE PREVALENCE OF ABNORMAL HEPATIC BIOCHEMISTRY AND HEPATOBILIARY MORBIDITY IN A COHORT OF PATIENTS WITH INFLAMMATORY BOWEL DISEASE, Annual Meeting on British-Society-of-Gasenterology, Publisher: B M J PUBLISHING GROUP, ISSN: 0017-5749
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- Citations: 1
Walker DG, Bancil AS, Rai PS, et al., 2011, ETHNIC VARIATION IN THE FREQUENCY OF IBD RELATED POLYMORPHISMS IN IRGM, ATG16L1 AND IL23R, Annual Meeting on British-Society-of-Gasenterology, Publisher: B M J PUBLISHING GROUP, Pages: A223-A223, ISSN: 0017-5749
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- Citations: 5
Mills SC, von Roon AC, Tekkis PP, et al., 2010, Crohn's disease., BMJ Clin Evid, Vol: 2010
INTRODUCTION: Crohn's disease is a chronic condition of the gastrointestinal tract. It is characterised by transmural, granulomatous inflammation that occurs in a discontinuous pattern, with a tendency to form fistulae. The cause is unknown but may depend on interactions between genetic predisposition, environmental triggers, and mucosal immunity. METHODS AND OUTCOMES: We conducted a systematic review and aimed to answer the following clinical questions: What are the effects of medical treatments to induce remission in adults with Crohn's disease? What are the effects of surgical interventions to induce and maintain remission in adults with small-bowel Crohn's disease? What are the effects of surgical interventions to induce remission in adults with colonic Crohn's disease? What are the effects of medical interventions to maintain remission in adults with Crohn's disease; and to maintain remission following surgery? What are the effects of lifestyle interventions to maintain remission in adults with Crohn's disease? We searched: Medline, Embase, The Cochrane Library, and other important databases up to December 2009 (Clinical Evidence reviews are updated periodically, please check our website for the most up-to-date version of this review). We included harms alerts from relevant organisations such as the US Food and Drug Administration (FDA) and the UK Medicines and Healthcare products Regulatory Agency (MHRA). RESULTS: We found 93 systematic reviews, RCTs, or observational studies that met our inclusion criteria. CONCLUSIONS: In this systematic review we present information relating to the effectiveness and safety of the following interventions: aminosalicylates, antibiotics, azathioprine/mercaptopurine, ciclosporin, corticosteroids (oral), enteral nutrition, fish oil, infliximab, methotrexate, probiotics, resection, segmental colectomy, smoking cessation, and strictureplasty.
Williams HRT, Cox IJ, Walker DG, et al., 2010, Differences in gut microbial metabolism are responsible for reduced hippurate synthesis in Crohn's disease, BMC GASTROENTEROLOGY, Vol: 10, ISSN: 1471-230X
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- Citations: 72
Williams HRT, Walker DG, North BV, et al., 2010, Metabonomics in Ulcerative Colitis, JOURNAL OF PROTEOME RESEARCH, Vol: 9, Pages: 2794-2795, ISSN: 1535-3893
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- Citations: 3
Walker DG, Williams HR, Pantelidis P, et al., 2010, The Three Common <i>CARD15/NOD2</i> Polymorphisms Associated With Crohn's Disease are Rare or Absent in a UK South Asian Crohn's Disease Population, Publisher: W B SAUNDERS CO-ELSEVIER INC, Pages: S684-S684, ISSN: 0016-5085
Monahan KJ, McNeil NIAN, Arnold J, et al., 2010, THE FREQUENCY OF GASTROINTESTINAL HAEMORRHAGE IN PATIENTS TREATED FOR ACUTE CORONARY SYNDROMES: AN OBSERVATIONAL STUDY, Annual General Meeting of the British-Society-of-Gastroenterology, Publisher: B M J PUBLISHING GROUP, Pages: A20-A21, ISSN: 0017-5749
Walker DG, Williams HRT, Orchard TR, 2010, THE PREVALENCE OF EXTRAINTESTINAL MANIFESTATIONS ASSOCIATED WITH INFLAMMATORY BOWEL DISEASE DIFFERS BETWEEN ETHNIC GROUPS IN THE UK, Annual General Meeting of the British-Society-of-Gastroenterology, Publisher: B M J PUBLISHING GROUP, Pages: A67-A67, ISSN: 0017-5749
Williams HRT, Cox IJ, Walker DG, et al., 2010, CORRELATING URINARY METABOLIC PROFILES WITH SEROLOGICAL AND GENETIC DETERMINANTS OF INFLAMMATORY BOWEL DISEASE, Annual General Meeting of the British-Society-of-Gastroenterology, Publisher: B M J PUBLISHING GROUP, Pages: A67-A68, ISSN: 0017-5749
Walker DG, Williams HRT, Orchard TR, 2010, TOLERABILITY OF THIOPURINES IN A UK SOUTH ASIAN INFLAMMATORY BOWEL DISEASE POPULATION, Annual General Meeting of the British-Society-of-Gastroenterology, Publisher: B M J PUBLISHING GROUP, Pages: A67-A67, ISSN: 0017-5749
Russo EA, Iacucci M, Lindsay JO, et al., 2010, Survey on the use of adalimumab as maintenance therapy in Crohn's disease in England and Ireland, EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, Vol: 22, Pages: 334-339, ISSN: 0954-691X
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- Citations: 13
Sato H, Williams HRT, Spagnolo P, et al., 2010, <i>CARD15</i>/<i>NOD2</i> polymorphisms are associated with severe pulmonary sarcoidosis, EUROPEAN RESPIRATORY JOURNAL, Vol: 35, Pages: 324-330, ISSN: 0903-1936
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- Citations: 55
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