Imperial College London


Faculty of EngineeringDepartment of Bioengineering

Senior Lecturer



t.ouldridge Website CV




320Royal School of MinesSouth Kensington Campus





I am just starting a Royal Society University Research Fellowship in the Bioengineering Department, where I will be building up a "Principles of Biomolecular Systems" group. I've previously been affiliated with Nick Jones' systems and signals group, the Doye / Louis biophysics groups in Oxford and the biochemical networks group of Pieter Rein ten Wolde in Amsterdam. 

My group probes the fundamental principles underlying complex biochemical systems through theoretical modelling, simulation and experiment. In particular, We focus on the interplay between the detailed biochemistry and the overall output of a process such as sensing, replication or self-assembly. We're inspired by natural systems, and aim to explore the possibilities of engineering artificial analogs. For more details, please refer to my Research Page.

Our take on the most recent developments in the field can be found in the blog that we run.



I'm always happy to hear from undergraduates, graduates and Postdocs that are excited by the research of my group. I will be offering several projects for MEng and MSc students, so please check them out. For excellent graduate students, it is possible to apply for funding through the Department or the College , so contact me if interested. I'm also potentially able to support applications for independent Postdoctoral positions, such as Imperial's excellent Research Fellowships that I myself benefited from.





Harrison RM, Romano F, Ouldridge TE, et al., 2019, Identifying physical causes of apparent enhanced cyclization of short DNA molecules with a coarse-grained model, Journal of Chemical Theory and Computation, Vol:15, ISSN:1549-9618, Pages:4660-4672

Brittain R, Jones N, Ouldridge T, 2019, Biochemical Szilard engines for memory-limited inference, New Journal of Physics, Vol:21, ISSN:1367-2630

Stopnitzky E, Still S, Ouldridge TE, et al., 2019, Physical limitations of work extraction from temporal correlations., Physical Review E, Vol:99, ISSN:1539-3755


Quast N, Ouldridge T, 2019, Simulation of DNA tile self-assembly

Ouldridge T, Abhishek D, 2019, Optimizing enzymatic catalysts for rapid turnover of substrates with low enzyme sequestration

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