BibTex format
@misc{Quast:2019,
author = {Quast, N and Ouldridge, T},
title = {Simulation of DNA tile self-assembly},
type = {Software},
year = {2019}
}
Publications
Citation
RIS format (EndNote, RefMan)
TY - GEN
AB - Submitted in accompaniment with final year report of MEng Project. DNA tile self-assembly is the spontaneous assembly of nano-structures made from short single-stranded DNA sequences. Successful assembly occurs within a narrow parameter window. Thisproject presents a model with which DNA self-assembly is simulated. Simulations for different tem-perature, sequence binding specificity and DNA tile concentrations indicate that: the growth rateof assemblies from uniform strand solutions is linear and highly temperature dependent; the aver-age nucleation times of assembly increase exponentially with temperature; high binding strengthsof boundary strands improve the stability of the complete assembly; locally high concentrations ofstrands seed the growth of the assembly; and locally low strand concentrations spatially direct thegrowth of the assembly. The source code is written in C.
AU - Quast,N
AU - Ouldridge,T
PY - 2019///
TI - Simulation of DNA tile self-assembly
ER -