Imperial College London


Faculty of EngineeringDepartment of Bioengineering

Reader in Biomolecular Systems



t.ouldridge Website CV




4.04Royal School of MinesSouth Kensington Campus





I am a Royal Society University Research Fellow in the Bioengineering Department, where I lead the "Principles of Biomolecular Systems" group

My group probes the fundamental principles underlying complex biochemical systems through theoretical modelling, simulation and experiment. In particular, We focus on the interplay between the detailed biochemistry and the overall output of a process such as sensing, replication or self-assembly. We're inspired by natural systems, and aim to explore the possibilities of engineering artificial analogs. For more details, including open positions and recent work, please refer to our group page.

Our take on the most recent developments in the field can be found in the blog that we run.





Climent-Catala A, Casas-Rodrigo I, Iyer S, et al., 2023, Evaluating DFHBI-responsive RNA light-up aptamers as fluorescent reporters for gene expression, Acs Synthetic Biology, Vol:12, ISSN:2161-5063, Pages:3754-3765

Ouldridge T, Wolpert DH, 2023, Thermodynamics of deterministic finite automata operating locally and periodically, New Journal of Physics, Vol:25, ISSN:1367-2630

Plesa T, Dack A, Ouldridge T, 2023, Integral feedback in synthetic biology: negative-equilibrium catastrophe, Journal of Mathematical Chemistry, Vol:61, ISSN:0259-9791, Pages:1980-2018

Qureshi BJ, Juritz J, Poulton JM, et al., 2023, A universal method for analyzing copolymer growth, Journal of Chemical Physics, Vol:158, ISSN:0021-9606, Pages:1-22

Seet I, Ouldridge TE, Doye JPK, 2023, Simulation of reversible molecular mechanical logic gates and circuits, Physical Review E: Statistical, Nonlinear, and Soft Matter Physics, Vol:107, ISSN:1539-3755

More Publications