109 results found
Tan T, Cabrita IZ, Hensman D, et al., 2010, Assessment of cardiac valve dysfunction in patients receiving cabergoline treatment for hyperprolactinaemia, CLINICAL ENDOCRINOLOGY, Vol: 73, Pages: 369-374, ISSN: 0300-0664
Cegla J, Tan TM, Bloom SR, 2010, Gut-brain cross-talk in appetite regulation, CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE, Vol: 13, Pages: 588-593, ISSN: 1363-1950
Addison ML, Minnion JS, Shillito JC, et al., 2010, Investigating the Metabolic Clearance and Degradation of the Anorexigenic Gut Hormone PYY3-36 as a Tool To Design Long-Acting Analogues of PYY3-36 for the Treatment of Obesity., 92nd Meeting and Expo of the Endocrine Society (ENDO 2010), Publisher: ENDOCRINE SOC, ISSN: 0163-769X
Dina R, Tan T, Grassilli C, et al., 2010, REPRODUCIBILITY OF Thy3 CATEGORY IN FNA OF THE THYROID AND THE EFFECT OF MDT DISCUSSION IN THE MANAGEMENT OF Thy3 CASES: A MULTILABORATORY SETTING, ACTA CYTOLOGICA, Vol: 54, Pages: 501-501, ISSN: 0001-5547
Banerjee A, Wynne K, Tan T, et al., 2009, High dose cabergoline therapy for a resistant macroprolactinoma during pregnancy, CLINICAL ENDOCRINOLOGY, Vol: 70, Pages: 812-813, ISSN: 0300-0664
Martin NM, Tan T, Meeran K, 2009, Dopamine agonists and hyperprolactinaemia, BRITISH MEDICAL JOURNAL, Vol: 338, ISSN: 0959-8146
Tan TMM, Caputo C, Medici F, et al., 2009, MELAS syndrome, diabetes and thyroid disease: the role of mitochondrial oxidative stress, CLINICAL ENDOCRINOLOGY, Vol: 70, Pages: 340-341, ISSN: 0300-0664
Tan TM, Hatfield EC, Thakker RV, et al., 2009, A legacy of tinnitus: multiple head and neck paragangliomas., Rare Tumors, Vol: 1, Pages: 88-89, ISSN: 2036-3605
We describe the case of a patient who presented with a right-sided glomus jugulare tumor and bilateral glomus vagale tumors. These proved to be nonmalignant paragangliomas on histopathological analysis. Genetic analysis revealed a germline heterozygous missense mutation (Pro81Leu) in the succinate dehydrogenase subunit D (SDHD) gene. We discuss the clinical presentations of the familial paraganglioma syndrome type 1, which is caused by mutations in SDHD, and the implications for the clinical diagnosis and care of such patients.
Tan TM, Caputo C, Medici F, et al., 2008, MELAS syndrome, diabetes and thyroid disease: the role of mitochondrial oxidative stress., Clin Endocrinol (Oxf)
Obesity, defined by a body mass index greater than 30kg/m2, claims an increasing number of lives every year, underscoring a dire need for effective therapeutic interventions. The origins of the obesity epidemic are complex, but commonly cited factors include the large quantities of calorie-rich food that are readily accessible in modern society; eating habits adapted to fast-paced lifestyles; low levels of physical activity; and genetic programs that have evolved, especially in populations prone to famine, to favor the storage of excess calories (i.e., the thrifty-gene theory). It is estimated that more than thirty percent of adults, and about fifteen percent of juveniles, are obese. These high rates have led to dramatic increases in diseases such as type 2 diabetes, cardiovascular and respiratory diseases, depression, and some forms of cancer.
Tan TM, Caputo C, Mehta A, et al., 2007, Pituitary macroadenomas: are combination antiplatelet and anticoagulant therapy contraindicated? A case report., J Med Case Rep, Vol: 1, ISSN: 1752-1947
BACKGROUND: Pituitary apoplexy is a life-threatening endocrine emergency that is caused by haemorrhage or infarction of the pituitary gland, commonly within a pituitary adenoma. Patients classically present with headache, ophthalmoplegia, visual field defects and altered mental state, but may present with a typical symptoms such as fever and altered conscious level. CASE PRESENTATION: A 57-year-old female with a known pituitary macroadenoma was treated for suspected acute coronary syndrome with aspirin, clopidogrel and full dose enoxaparin. She developed a severe and sudden headache, nausea and vomiting and visual deterioration. A CT scan showed haemorrhage into the pituitary macroadenoma. She underwent neurosurgical decompression. Post-operatively her visual fields and acuity returned to baseline. She was continued on hydrocortisone and thyroxine replacement on discharge. CONCLUSION: This case illustrates the risks of anticoagulation in a patient with a known pituitary macroadenoma, and raises the issue of whether these tumours present a relative contraindication to the use of dual antiplatelet and anticoagulation in acute coronary syndrome.
Tan TMM, Vanderpump M, Khoo B, et al., 2004, Somatostatin infusion lowers plasma ghrelin withoug reducing appetite in adults with Pradi-Willi syndrome, JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, Vol: 89, Pages: 4162-4165, ISSN: 0021-972X
Beaumont NJ, Skinner VO, Tan TMM, et al., 2003, Ghrelin can bind to a species of high density lipoprotein associated with paraoxonase, JOURNAL OF BIOLOGICAL CHEMISTRY, Vol: 278, Pages: 8877-8880, ISSN: 0021-9258
Chan NN, Baldeweg S, Tan TMM, et al., 2001, Inhaled insulin in type 1 diabetes, LANCET, Vol: 357, Pages: 1979-1979, ISSN: 0140-6736
Chan NN, Baldeweg SE, Tan TMM, et al., 2001, Glucosamine sulphate and osteoarthritis, LANCET, Vol: 357, Pages: 1618-1619, ISSN: 0140-6736
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