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@article{Dong:2022:10.1016/j.coemr.2021.100315,
author = {Dong, J and Jones, S and Tabbakh, Y and Tan, TMM},
doi = {10.1016/j.coemr.2021.100315},
journal = {Current Opinion in Endocrine and Metabolic Research},
title = {The clinical outcomes, appetite and metabolic effects of sleeve gastrectomy and Roux-en-Y gastric bypass: A comparative review},
url = {http://dx.doi.org/10.1016/j.coemr.2021.100315},
volume = {22},
year = {2022}
}

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TY  - JOUR
AB  - Bariatric surgery is a highly effective treatment for obesity, leading to sustained weight loss and improvements in obesity-related comorbidities. Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) are the commonest bariatric procedures performed. These procedures lead to weight loss via increasing satiety and altering food preferences, rather than restriction and malabsorption. RYGB and SG result in markedly different postoperative anatomy and thus may have differential effects on the gut–brain axis. This review aims to compare the postoperative clinical outcomes and changes in appetite following RYGB and SG. We review evidence for the mechanisms underlying each procedure, including changes to gut hormone signalling, bile acids, vagal signalling, and the gut microbiome. We also highlight areas of controversy that require further study.
AU  - Dong,J
AU  - Jones,S
AU  - Tabbakh,Y
AU  - Tan,TMM
DO  - 10.1016/j.coemr.2021.100315
PY  - 2022///
TI  - The clinical outcomes, appetite and metabolic effects of sleeve gastrectomy and Roux-en-Y gastric bypass: A comparative review
T2  - Current Opinion in Endocrine and Metabolic Research
UR  - http://dx.doi.org/10.1016/j.coemr.2021.100315
VL  - 22
ER  -

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