Summary
Thomas Thum is Professor and Director of the Institute of Molecular and Translational Therapeutic Strategies at Hannover Medical School in Germany. Recently, he joined Imperial College as Visiting Professor to strengthen collaborative research activities.
Professor Thum studied Medicine at the Hannover Medical School and received a PhD from the Imperial College London and as a clinician is specialized in Internal Medicine and Cardiology. His major translational interests are to uncover the roles of regulatory RNA molecules, such as microRNAs and long-non-coding RNAs in cardiovascular and transplantation medicine. He is particularly interested into heart failure and performed landmark studies to show the therapeutic and diagnostic potential of microRNAs and respective antagonists. Prof. Thum published over 150 papers in leading scientific journals such as Nature, Nature Genetics, Nature Communication, Lancet, JACC and Circulation. He is member of the Editorial Board of many journals such as Circulation Research, ATVB or the Journal of Molecular and Cellular Cardiology. Prof. Thum is active member of many task forces and nuclei of cardiovascular societies including those of the European Society of Cardiology and the International Society of Heart Research. Prof. Thum is recipient of many national and international awards, e.g. the Outstanding Achievement Award from the European Society of Cardiology. He is coordinator and co-coordinator of several international consortia, e.g. for an intercontinental grant obtained from the Fondation Leducq or the European Union.
Publications
Journals
Van Aelst LN, Summer G, Li S, et al., 2016, RNA Profiling in Human and Murine Transplanted Hearts: Identification and Validation of Therapeutic Targets for Acute Cardiac and Renal Allograft Rejection., American Journal of Transplantation, Vol:16, ISSN:1600-6143, Pages:99-110
Kunz M, Xiao K, Liang C, et al., 2015, Bioinformatics of cardiovascular miRNA biology, Journal of Molecular and Cellular Cardiology, Vol:89, ISSN:0022-2828, Pages:3-10
Piccoli M-T, Gupta SK, Thum T, 2015, Noncoding RNAs as regulators of cardiomyocyte proliferation and death, Journal of Molecular and Cellular Cardiology, Vol:89, ISSN:0022-2828, Pages:59-67
Soerensen-Zender I, Bhayana S, Susnik N, et al., 2015, Zinc-α2-Glycoprotein Exerts Antifibrotic Effects in Kidney and Heart, Journal of the American Society of Nephrology, Vol:26, ISSN:1046-6673, Pages:2659-2668
Derda AA, Thum S, Lorenzen JM, et al., 2015, Blood-based microRNA signatures differentiate various forms of cardiac hypertrophy, International Journal of Cardiology, Vol:196, ISSN:0167-5273, Pages:115-122