Dr Theresa Page received her DPhil in transplantation biology from the Nuffield Department of Surgery in Oxford, and then moved to London where she joined the Charing Cross Sunley Research Centre, later to become part of Imperial College. Her studies here began with work on cytokine signalling mechanisms in T cells, and later moved to examining signal transduction mechanisms and pathways in human macrophage biology, with emphasis on the role of tyrosine kinases in TLR signalling and inflammation. Dr Page joined the section of Renal and Vascular biology, now part of the centre for inflammatory disease, in Imperial College in 2013.
My main interests are in the pathogenesis of antibody mediated glomerulonephritis and systemic vascular disease. In particular I have an interest in the role of DAMPs and how cells of the monocyte/macrophage and neutrophil lineage participate in the pathogenesis of IgA Nephropathy and ANCA vasculitis. My work concentrates on human disease and aims to understand the mechanisms driving both the chronic inflammation and fibrosis that characterises these conditions.
et al., 2021, Danger-associated molecular pattern molecules and the receptor for advanced glycation end products enhance ANCA-induced responses, Rheumatology, Vol:61, ISSN:1462-0324, Pages:834-845
et al., 2019, 210. The calprotectin/rage/ TLR4 axis in anca-associated vasculitis, Rheumatology, Vol:58, ISSN:1462-0324, Pages:ii91-ii91
et al., 2018, Excessive neutrophil extracellular trap formation in ANCA-associated vasculitis is independent of ANCA, Kidney International, Vol:94, ISSN:0085-2538, Pages:139-149
et al., 2018, Bruton's tyrosine kinase regulates TLR7/8-induced TNF transcription via nuclear factor-κB recruitment, Biochemical and Biophysical Research Communications, Vol:499, ISSN:0006-291X, Pages:260-266
et al., 2017, ANCA-ASSOCIATED VASCULITIS PATIENTS EXHIBIT REDUCED SERUM LEVELS OF SOLUBLE RAGE (SRAGE), Rheumatology, Vol:56, ISSN:1462-0324, Pages:118-118