Summary
Dr Theresa Page received her DPhil in transplantation biology from the Nuffield Department of Surgery in Oxford, and then moved to London where she joined the Charing Cross Sunley Research Centre, later to become part of Imperial College. Her studies here began with work on cytokine signalling mechanisms in T cells, and later moved to examining signal transduction mechanisms and pathways in human macrophage biology, with emphasis on the role of tyrosine kinases in TLR signalling and inflammation. Dr Page joined the section of Renal and Vascular biology, now part of the centre for inflammatory disease, in Imperial College in 2013.
My main interests are in the pathogenesis of antibody mediated glomerulonephritis and systemic vascular disease. In particular I have an interest in the role of DAMPs and how cells of the monocyte/macrophage and neutrophil lineage participate in the pathogenesis of IgA Nephropathy and ANCA vasculitis. My work concentrates on human disease and aims to understand the mechanisms driving both the chronic inflammation and fibrosis that characterises these conditions.
Publications
Journals
Page TH, Chiappo D, Brunini F, et al., 2022, Danger-associated molecular pattern molecules and the receptor for advanced glycation end products enhance ANCA-induced responses, Rheumatology, Vol:61, ISSN:1462-0324, Pages:834-845
Page T, Brunini F, Caparros JG, et al., 2019, 210. The calprotectin/rage/ TLR4 axis in anca-associated vasculitis, Rheumatology, Vol:58, ISSN:1462-0324, Pages:ii91-ii91
Kraaij T, Kamerling SWA, van Dam LS, et al., 2018, Excessive neutrophil extracellular trap formation in ANCA-associated vasculitis is independent of ANCA, Kidney International, Vol:94, ISSN:0085-2538, Pages:139-149
Page TH, Urbaniak AM, Espirito Santo AI, et al., 2018, Bruton's tyrosine kinase regulates TLR7/8-induced TNF transcription via nuclear factor-κB recruitment, Biochemical and Biophysical Research Communications, Vol:499, ISSN:0006-291X, Pages:260-266
Brunini F, Cao JJL, Dudhiya F, et al., 2017, ANCA-ASSOCIATED VASCULITIS PATIENTS EXHIBIT REDUCED SERUM LEVELS OF SOLUBLE RAGE (SRAGE), Rheumatology, Vol:56, ISSN:1462-0324, Pages:118-118