Imperial College London
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ProfessorThomasChurcher

Faculty of Medicine, School of Public Health

Professor of Infectious Disease Dynamics
 
 
 
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Contact

 

thomas.churcher

 
 
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Location

 

G35Medical SchoolSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Sherrard-Smith:2022:10.1038/s41467-022-30700-1,
author = {Sherrard-Smith, E and Ngufor, C and Sanou, A and Guelbeogo, M and NGuessan, R and Elobolobo, E and Saute, F and Varela, K and Chaccour, C and Zulliger, R and Wagman, J and Robertson, ML and Rowland, M and Donnelly, M and Gonahasa, S and Staedke, S and Kolaczinski, J and Churcher, T},
doi = {10.1038/s41467-022-30700-1},
journal = {Nature Communications},
title = {Inferring the epidemiological benefit of indoor vector control interventions against malaria from mosquito data},
url = {http://dx.doi.org/10.1038/s41467-022-30700-1},
volume = {13},
year = {2022}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - The cause of malaria transmission has been known for over a century but it is still unclear whether entomological measures are sufficiently reliable to inform policy decisions in human health. Decision-making on the effectiveness of new insecticide-treated nets (ITNs) and the indoor residual spraying of insecticide (IRS) have been based on epidemiological data, typically collected in cluster-randomised control trials. The number of these trials that can be conducted is limited. Here we use a systematic review to highlight that efficacy estimates of the same intervention may vary substantially between trials. Analyses indicate that mosquito data collected in experimental hut trials can be used to parameterize mechanistic models for Plasmodium falciparum malaria and reliably predict the epidemiological efficacy of quick-acting, neuro-acting ITNs and IRS. Results suggest that for certain types of ITNs and IRS using this framework instead of clinical endpoints could support policy and expedite the widespread use of novel technologies.
AU  - Sherrard-Smith,E
AU  - Ngufor,C
AU  - Sanou,A
AU  - Guelbeogo,M
AU  - NGuessan,R
AU  - Elobolobo,E
AU  - Saute,F
AU  - Varela,K
AU  - Chaccour,C
AU  - Zulliger,R
AU  - Wagman,J
AU  - Robertson,ML
AU  - Rowland,M
AU  - Donnelly,M
AU  - Gonahasa,S
AU  - Staedke,S
AU  - Kolaczinski,J
AU  - Churcher,T
DO  - 10.1038/s41467-022-30700-1
PY  - 2022///
SN  - 2041-1723
TI  - Inferring the epidemiological benefit of indoor vector control interventions against malaria from mosquito data
T2  - Nature Communications
UR  - http://dx.doi.org/10.1038/s41467-022-30700-1
UR  - https://www.nature.com/articles/s41467-022-30700-1
UR  - http://hdl.handle.net/10044/1/97565
VL  - 13
ER  -
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