DrTimothyDawes

Faculty of Medicine, National Heart & Lung Institute

Honorary Clinical Lecturer

Contact

Location

MRC London Institute of Medical Sciences, 111 ISDRobert Steiner MR unitHammersmith Campus

Summary

I am an post-CCT fellow in paediatric cardiac anaesthesia with a parallel research interest in cardiac imaging. I hope to use machine learning to improve the use of high-resolution imaging as a biomarker of cardiac disease.

Interests

The use of three-dimensional modelling to understand cardiac structure and function
The application of machine learning approaches to identify the environmental, physiological and genetic determinants of cardiac dysfunction
Survival analysis from multi-modal datasets

Selected Publications

Journal Articles

Dawes TJW, McCabe C, Dimopoulos K, et al.Dawes TJW, McCabe C, Dimopoulos K, Stewart I, Bax S, Harries C, Samaranayake CB, Kempny A, Molyneaux PL, Seitler S, Semple T, Li W, George PM, Kouranos V, Chua F, Renzoni EA, Kokosi M, Jenkins G, Wells AU, Wort SJ, Price LC close, 2023, Phosphodiesterase 5 inhibitor treatment and survival in interstitial lung disease pulmonary hypertension: A Bayesian retrospective observational cohort study, Respirology, Vol:28, ISSN:1323-7799, Pages:262-272

Meyer H, Dawes T, Serrani M, et al.Meyer H, Dawes T, Serrani M, Bai W, Tokarczuk P, Cai J, Simoes Monteiro de Marvao A, Henry A, Lumbers T, Gierten J, Thumberger T, Wittbrodt J, Ware J, Rueckert D, Matthews P, Prasad S, Costantino M, Cook S, Birney E, O'Regan D close, 2020, Genetic and functional insights into the fractal structure of the heart, Nature, Vol:584, ISSN:0028-0836, Pages:589-594

Bello G, Dawes T, Duan J, et al.Bello G, Dawes T, Duan J, Biffi C, Simoes Monteiro de Marvao A, Howard L, Gibbs S, Wilkins M, Cook S, Rueckert D, O'Regan D close, 2019, Deep learning cardiac motion analysis for human survival prediction, Nature Machine Intelligence, Vol:1, ISSN:2522-5839, Pages:95-104

Dawes T, Cai J, Quinlan M, et al.Dawes T, Cai J, Quinlan M, Simoes Monteiro de Marvao A, Ostowski P, Tokarczuk P, Watson G, Wharton J, Howard L, Gibbs J, Cook S, Wilkins M, O'Regan DP close, 2018, Fractal analysis of right ventricular trabeculae in pulmonary hypertension, Radiology, Vol:288, ISSN:0033-8419, Pages:386-395

Schafer S, de Marvao A, Adami E, et al.Schafer S, de Marvao A, Adami E, Fiedler LR, Ng B, Khin E, Rackham O, van Heesch S, Pua CJ, Kui M, Walsh R, Tayal U, Prasad SK, Dawes TJW, Ko NSJ, Sim D, Chan LLH, Chin CWL, Mazzarotto F, Barton PJ, Kreuchwig F, de Kleijn DPV, Totman T, Biffi C, Tee N, Rueckert D, Schneider V, Faber A, Regitz-Zagrosek V, Seidman JG, Seidman CE, Linke WA, Kovalik J, O'Regan D, Ware JS, Hubner N, Cook SA close, 2017, Titin-truncating variants affect heart function in disease cohorts and the general population, Nature Genetics, Vol:49, ISSN:1546-1718, Pages:46-53

Dawes TJW, Gandhi A, de Marvao A, et al.Dawes TJW, Gandhi A, de Marvao A, Buzaco R, Tokarczuk P, Quinlan M, Durighel G, Diamond T, Monje Garcia L, de Cesare A, Cook SA, O'Regan DP close, 2016, Pulmonary artery stiffness is independently associated with right ventricular mass and function: a cardiac magnetic resonance study., Radiology, Vol:280, ISSN:1527-1315

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