Publications

BibTex format

@techreport{Grassly:2020:10.25561/78439,
author = {Grassly, N and Pons, Salort M and Parker, E and White, P and Ainslie, K and Baguelin, M and Bhatt, S and Boonyasiri, A and Boyd, O and Brazeau, N and Cattarino, L and Ciavarella, C and Cooper, L and Coupland, H and Cucunuba, Perez Z and Cuomo-Dannenburg, G and Dighe, A and Djaafara, A and Donnelly, C and Dorigatti, I and van, Elsland S and Ferreira, Do Nascimento F and Fitzjohn, R and Fu, H and Gaythorpe, K and Geidelberg, L and Green, W and Hallett, T and Hamlet, A and Hayes, S and Hinsley, W and Imai, N and Jorgensen, D and Knock, E and Laydon, D and Lees, J and Mangal, T and Mellan, T and Mishra, S and Nedjati, Gilani G and Nouvellet, P and Okell, L and Ower, A and Parag, K and Pickles, M and Ragonnet-Cronin, M and Stopard, I and Thompson, H and Unwin, H and Verity, R and Vollmer, M and Volz, E and Walker, P and Walters, C and Wang, H and Wang, Y and Watson, O and Whittaker, C and Whittles, L and Winskill, P and Xi, X and Ferguson, N},
doi = {10.25561/78439},
title = {Report 16: Role of testing in COVID-19 control},
url = {http://dx.doi.org/10.25561/78439},
year = {2020}
}

Download

RIS format (EndNote, RefMan)

TY  - RPRT
AB  - The World Health Organization has called for increased molecular testing in response to the COVID-19 pandemic, but different countries have taken very different approaches. We used a simple mathematical model to investigate the potential effectiveness of alternative testing strategies for COVID-19 control. Weekly screening of healthcare workers (HCWs) and other at-risk groups using PCR or point-of-care tests for infection irrespective of symptoms is estimated to reduce their contribution to transmission by 25-33%, on top of reductions achieved by self-isolation following symptoms. Widespread PCR testing in the general population is unlikely to limit transmission more than contact-tracing and quarantine based on symptoms alone, but could allow earlier release of contacts from quarantine. Immunity passports based on tests for antibody or infection could support return to work but face significant technical, legal and ethical challenges. Testing is essential for pandemic surveillance but its direct contribution to the prevention of transmission is likely to be limited to patients, HCWs and other high-risk groups.
AU  - Grassly,N
AU  - Pons,Salort M
AU  - Parker,E
AU  - White,P
AU  - Ainslie,K
AU  - Baguelin,M
AU  - Bhatt,S
AU  - Boonyasiri,A
AU  - Boyd,O
AU  - Brazeau,N
AU  - Cattarino,L
AU  - Ciavarella,C
AU  - Cooper,L
AU  - Coupland,H
AU  - Cucunuba,Perez Z
AU  - Cuomo-Dannenburg,G
AU  - Dighe,A
AU  - Djaafara,A
AU  - Donnelly,C
AU  - Dorigatti,I
AU  - van,Elsland S
AU  - Ferreira,Do Nascimento F
AU  - Fitzjohn,R
AU  - Fu,H
AU  - Gaythorpe,K
AU  - Geidelberg,L
AU  - Green,W
AU  - Hallett,T
AU  - Hamlet,A
AU  - Hayes,S
AU  - Hinsley,W
AU  - Imai,N
AU  - Jorgensen,D
AU  - Knock,E
AU  - Laydon,D
AU  - Lees,J
AU  - Mangal,T
AU  - Mellan,T
AU  - Mishra,S
AU  - Nedjati,Gilani G
AU  - Nouvellet,P
AU  - Okell,L
AU  - Ower,A
AU  - Parag,K
AU  - Pickles,M
AU  - Ragonnet-Cronin,M
AU  - Stopard,I
AU  - Thompson,H
AU  - Unwin,H
AU  - Verity,R
AU  - Vollmer,M
AU  - Volz,E
AU  - Walker,P
AU  - Walters,C
AU  - Wang,H
AU  - Wang,Y
AU  - Watson,O
AU  - Whittaker,C
AU  - Whittles,L
AU  - Winskill,P
AU  - Xi,X
AU  - Ferguson,N
DO  - 10.25561/78439
PY  - 2020///
TI  - Report 16: Role of testing in COVID-19 control
UR  - http://dx.doi.org/10.25561/78439
UR  - https://www.imperial.ac.uk/media/imperial-college/medicine/mrc-gida/2020-04-23-COVID19-Report-16.pdf
UR  - http://hdl.handle.net/10044/1/78439
ER  -

Download

ProfessorTimothyHallett

Contact

Location

Summary

Citation

BibTex format

RIS format (EndNote, RefMan)