Imperial College London
Portrait Picture

DrTimothy MilesRawson

Faculty of Medicine, Department of Infectious Disease

Honorary Clinical Lecturer
 
 
 
//

Contact

 

timothy.rawson07 Website

 
 
//

Location

 

Commonwealth BuildingHammersmith Campus

//

Summary

 

Publications

Citation

BibTex format

@article{Herrero:2018:10.1109/TBME.2017.2787423,
author = {Herrero, P and Rawson, TM and Philip, A and Moore, LSP and Holmes, AH and Georgiou, P},
doi = {10.1109/TBME.2017.2787423},
journal = {IEEE Transactions on Biomedical Engineering},
pages = {2231--2236},
title = {Closed-loop control for precision antimicrobial delivery: an In silico proof-of-concept},
url = {http://dx.doi.org/10.1109/TBME.2017.2787423},
volume = {65},
year = {2018}
}
Download

RIS format (EndNote, RefMan)

TY  - JOUR
AB  - IEEE Objective: Inappropriate dosing of patients with antibiotics is a driver of antimicrobial resistance, toxicity, and poor outcomes of therapy. In this paper, we investigate, in silico, the hypothesis that the use of a closed-loop control system could improve the attainment of pharmacokinetic-pharmacodynamic targets for antimicrobial therapy, where wide variations in target attainment have been reported. This includes patients in critical care, patients with renal disease and patients with obesity.
AU  - Herrero,P
AU  - Rawson,TM
AU  - Philip,A
AU  - Moore,LSP
AU  - Holmes,AH
AU  - Georgiou,P
DO  - 10.1109/TBME.2017.2787423
EP  - 2236
PY  - 2018///
SN  - 0018-9294
SP  - 2231
TI  - Closed-loop control for precision antimicrobial delivery: an In silico proof-of-concept
T2  - IEEE Transactions on Biomedical Engineering
UR  - http://dx.doi.org/10.1109/TBME.2017.2787423
UR  - http://hdl.handle.net/10044/1/56020
VL  - 65
ER  -
Download