Publications
146 results found
Dharmarajah B, Lane TRA, Moore HM, et al., 2014, The Future of Phlebology in Europe, PHLEBOLOGY, Vol: 29, Pages: 181-185, ISSN: 0268-3555
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- Citations: 2
Rao R, Lane T, Franklin I, et al., 2014, A systematic review of open repair versus fenestrated endovascular aneurysm repair of juxtarenal aneurysms, Annual Meeting of the Society-of-Academic-and-Research-Surgery, Publisher: WILEY-BLACKWELL, Pages: 39-39, ISSN: 0007-1323
Lane TRA, Franklin IJ, Davies AH, 2014, The AVULS Trial - is simultaneous better?, Annual Meeting of the Society-of-Academic-and-Research-Surgery, Publisher: WILEY-BLACKWELL, Pages: 6-6, ISSN: 0007-1323
Lane TRA, Franklin IJ, Davies AH, 2014, Creating a predictive model of vein outcomes, Annual Meeting of the Society-of-Academic-and-Research-Surgery, Publisher: WILEY-BLACKWELL, Pages: 38-38, ISSN: 0007-1323
Moore HM, Head K, Shalhoub J, et al., 2014, The UK varicose vein story 1989-2010, Annual Meeting of the Society-of-Academic-and-Research-Surgery, Publisher: WILEY-BLACKWELL, Pages: 50-50, ISSN: 0007-1323
Moore HM, Adesina-Georgiadis N, Moon KH, et al., 2014, The view of surgeons, general practitioners and patients on patient follow- up following varicose vein interventions in the UK, Annual Meeting of the Society-of-Academic-and-Research-Surgery, Publisher: WILEY-BLACKWELL, Pages: 51-51, ISSN: 0007-1323
Lane TRA, 2014, Outcomes in Varicose Vein Disease
IntroductionVaricose veins are a common problem with 25-50% of the population symptomatically affected, and chronic venous disease leads to significant impairments in quality of life with substantial health system cost implications. Significant variability exists in the symptoms suffered by patients, the treatment offered and the outcomes achieved. Identification of the optimal treatment pathways for patients remains difficult.Aimsi. To ascertain primary care disease knowledge.ii. To assess what affects treatment and identify which patients benefit most.iii. To generate a predictive model of varicose vein outcomes.iv. To assess the impact of altering treatment of varicosities in the context ofendovenous truncal vein ablationv. ToinvestigatetheearlyimpactofnewtechnologiesMethodsi. Two survey studies were completed:⁃ 21 questions assessing venous disease management pathways wasdisseminated to General Practitioners.⁃ 19 questions assessing the management of superficial venousthrombosis and was distributed to General Practitioners and VascularSurgeons.ii. A cohort of consecutive patients with symptomatic chronic venous diseasewere assessed and completed quality of life questionnaires pre and post- intervention.iii. Uni-variable and multi-variable analysis of patient cohort data to facilitatethe creation of generalised model of venous treatment outcomesiv. A randomised clinical trial assessing the timing of varicosity avulsion in thecontext of local anaesthetic endovenous truncal ablation.⁃ Ambulatory Varicosity avUlsion Later or Synchronised (AVULS) trial.v. Assessmentofnewtechnologies⁃ The European Sapheon Closure system Observed ProspectivE(eSCOPE) study a multi-site cohort observational study ofcyanoacrylate glue occlusion of truncal vein incompetence⁃ The VNUS Versus Clarivein for Varicose Veins (VVCVV) multi-centrerandomised clinical trial comparing the procedural pain profile of radiofrequency and mechanochemical ablation.Resultsi. Education outcomes⁃ 138 response
Dharmarajah B, Thapar A, Salem J, et al., 2014, Impact of risk scoring on decision-making in symptomatic moderate carotid atherosclerosis, BRITISH JOURNAL OF SURGERY, Vol: 101, Pages: 475-480, ISSN: 0007-1323
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- Citations: 4
Kelleher D, Lane TRA, Franklin IJ, et al., 2014, Socio-economic impact of endovenous thermal ablation techniques, LASERS IN MEDICAL SCIENCE, Vol: 29, Pages: 493-499, ISSN: 0268-8921
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- Citations: 6
Lane TRA, Varatharajan L, Kelleher D, et al., 2014, Phlebectomy timing does matter - results of the AVULS trial, 48th Annual Scientific Meeting of the Vascular-Society-of-Great-Britain-and-Ireland, Publisher: WILEY-BLACKWELL, Pages: 5-5, ISSN: 0007-1323
Bootun R, Lane TRA, Davies AH, 2014, Foam sclerotherapy for truncal ablation, Sclerotherapy: Procedures, Potential Complications and Clinical Outcomes, Pages: 37-46, ISBN: 9781633216198
Varicose veins are known to affect approximately one third of the population and lead to reduced quality of life for patients. The traditional method of treatment has been surgery, but over the past decade, minimally invasive techniques have gained increasing prominence. These have been found to be easier to administer, less expensive, have shorter recovery periods and enables a more rapid return to normal activities. One such method is the use of foam sclerotherapy for the treatment of truncal incompetence and it has increased in popularity since the 1990s. Compared to surgery, the procedure is much cheaper and the recovery time is fairly rapid post-procedure. Patients have also reported improved health related quality of life afterwards. Foam sclerotherapy has been noted to be associated with a high efficacy of around 90% in the short term. In the longer term, however, foam sclerotherapy has an elevated recurrence rate when compared to surgery and thermal endovenous ablation techniques. In addition, it is associated with certain adverse events, such as visual disturbance and thrombophlebitis. These are, nonetheless, relatively uncommon and, out of the millions of procedures carried out so far, it has proven to be a safe procedure.
Lane TRA, Sritharan K, Herbert JR, et al., 2013, Management of chronic venous disease by primary care, PHLEBOLOGY, Vol: 28, Pages: 299-304, ISSN: 0268-3555
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- Citations: 10
Lane TRA, Kelleher D, Franklin IJ, et al., 2013, Inferior vena cava filters: when, where, why?, PHLEBOLOGY, Vol: 28, Pages: 177-179, ISSN: 0268-3555
Onida S, Lane TRA, Davies AH, 2013, Varicose veins and their management, Surgery (United Kingdom), Vol: 31, Pages: 211-217, ISSN: 0263-9319
Varicose veins are a common condition, affecting up to a quarter of the UK population. They have been shown to negatively impact on patients' quality of life and are an important cause of morbidity. The management of varicose veins may be conservative (including lifestyle changes and compression hosiery) or surgical. Operative treatment aims to disconnect the superficial and deep venous systems at the sites of venous incompetence; traditionally saphenofemoral and saphenopopliteal junction ligation with or without stripping were the mainstay of treatment. In the last decade surgical treatment has been moving towards minimally invasive endovascular techniques, including thermal ablation (by means of radiofrequency, laser technology, steam), cryoablation and mechanochemical ablation. These are less invasive than open surgery and may be done under local anaesthesia. This article discusses the epidemiology, diagnosis and management of varicose veins, including the latest endovascular and targeted open surgical techniques such as haemodynamic surgery and variceal ablation. © 2013 Elsevier Ltd. All rights reserved.
Lane TRA, Shepherd AC, Gohel MS, et al., 2013, Vein diameter is associated with disease severity not quality of life impairment, Joint Meeting of the Section-of-Surgery of the Royal-Society-of-Medicine / Annual Meeting of the Society-of-Academic-and-Research-Surgery, Publisher: WILEY-BLACKWELL, Pages: 46-46, ISSN: 0007-1323
Lane TRA, Sritharan K, Franklin IJ, et al., 2013, Primary and secondary care attitudes to the management of superficial venous thrombosis, Joint Meeting of the Section-of-Surgery of the Royal-Society-of-Medicine / Annual Meeting of the Society-of-Academic-and-Research-Surgery, Publisher: WILEY-BLACKWELL, Pages: 39-39, ISSN: 0007-1323
Sounderajah V, Moore HM, Thapar A, et al., 2013, Microemboli identified in the right heart during thermoablation of varicose veins, Joint Meeting of the Section-of-Surgery of the Royal-Society-of-Medicine / Annual Meeting of the Society-of-Academic-and-Research-Surgery, Publisher: WILEY-BLACKWELL, Pages: 44-45, ISSN: 0007-1323
Moore HM, Lane TRA, Franklin IJ, et al., 2013, A UK disparity in the treatment of patients with varicose veins has been identified, Joint Meeting of the Section-of-Surgery of the Royal-Society-of-Medicine / Annual Meeting of the Society-of-Academic-and-Research-Surgery, Publisher: WILEY-BLACKWELL, Pages: 40-40, ISSN: 0007-1323
Sounderajah V, Moore HM, Thapar A, et al., 2013, Microemboli present in the right heart during thermoablation of varicose veins, 47th Annual Scientific Meeting of the Vascular-Society-of-Great-Britain-and-Ireland, Publisher: WILEY-BLACKWELL, Pages: 8-8, ISSN: 0007-1323
Lane T, Franklin I, Davies A, 2013, Re. 'An Online Patient Completed Aberdeen Varicose Vein Questionnaire Can Help to Guide Primary Care Referrals', EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY, Vol: 45, Pages: 404-404, ISSN: 1078-5884
Moore HM, Lane TRA, Thapar A, et al., 2013, The European burden of primary varicose veins, PHLEBOLOGY, Vol: 28, Pages: 141-147, ISSN: 0268-3555
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- Citations: 22
Lane TRA, Dharmarajah B, Kelleher D, et al., 2013, Short-term gain for long-term pain? Which patients should be treated and should we ration?, PHLEBOLOGY, Vol: 28, Pages: 148-152, ISSN: 0268-3555
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- Citations: 5
Qureshi MI, Lane TRA, Moore HM, et al., 2013, Patterns of short saphenous vein incompetence, PHLEBOLOGY, Vol: 28, Pages: 47-50, ISSN: 0268-3555
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- Citations: 4
Kuet ML, Lane TRA, Franklin IJ, et al., 2013, A Study To Compare Disease Specific Quality Of Life Scoring Systems In Patients With Varicose Veins, Phoenix, USA
Lane TRA, Shepherd AC, Gohel MS, et al., 2013, Big Veins, Big Deal - Vein Diameter Affects Disease Severity, not Quality of Life, Journal of Vascular Surgery: Venous and Lymphatic Disorders, Vol: 1, Pages: 101-101
Lane TRA, Franklin IJ, Davies AH, 2013, RE: Ward A, Abisi S, Braithwaite BD. An Online Patient Completed Aberdeen Varicose Vein Questionnaire Can Help to Guide Primary Care Referrals, European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery
Onida S, Lane TRA, Davies AH, 2013, Improving the management of varicose veins., Practitioner, Vol: 257, Pages: 21-3, ISSN: 0032-6518
Up to 30% of the UK population are affected by varicose veins. They are a manifestation of increased venous pressure in the lower limb caused by impaired venous return. Primary varicosities result from poor drainage from the superficial to the deep venous system. Secondary varicosities arise as a result of underlying pathology impeding venous drainage, such as deep venous thrombosis or increased intra-abdominal pressure caused by a mass, pregnancy or obesity. Patients with bleeding varicose veins should be referred to a vascular service immediately. Referral is also indicated in the following cases: symptomatic primary or recurrent varicose veins; lower limb skin changes thought to be caused by chronic venous insufficiency; superficial vein thrombosis and suspected venous incompetence; a venous leg ulcer or healed venous leg ulcer. Imaging is crucial in the assessment of the superficial and deep venous system to enable assessment of venous competence. The gold standard imaging technique is colour duplex ultrasonography. Duplex ultrasound should be used to confirm the diagnosis of varicose veins and the extent of truncal reflux, and to plan treatment for patients with suspected primary or recurrent varicose veins. Superficial vein ligation, phlebectomy and stripping have been the mainstay of treatment. In recent years, new techniques have been developed that are minimally invasive, enabling treatment of superficial venous incompetence with reduced morbidity. NICE recommends that endothermal ablation, in the form of radiofrequency or laser treatment, should be offered as treatment for patients with confirmed varicose veins and truncal reflux.
Shepherd AC, Lane TR, Davies AH, 2012, The natural progression of chronic venous disorders: An overview of available information from longitudinal studies, Phlebolymphology, Vol: 19, Pages: 36-45, ISSN: 1286-0107
Chronic venous disorders remain a common problem worldwide; however, despite increasing research into novel endovenous therapies for the treatment of superficial venous disease, the natural history of primary venous disorders remains poorly understood. The following article provides a review of the longitudinal studies evaluating the progression of chronic venous disorders in the published literature. This includes a summary of the rate of development of venous disease in asymptomatic limbs and the rate of progression of venous disease in terms of hemodynamic, anatomical, and clinical progression including the development of skin changes and venous ulceration. Venous disorders, including varicose veins and superficial venous insufficiency, are a common pathology, thought to affect between 15% and 40% of the adult population. 1-2 They have plagued mankind for thousands of years and there is documentation of their existence from as early as 3500 BC. 3 In the last decade, the development of endovenous techniques has led to a rapid increase in the popularity of many novel therapies including thermal and chemical ablation techniques. 4-7 Yet, despite the large number of research studies supporting the use of new devices, the etiology and natural history of the progression of venous disease remains poorly understood. Evidence from clinical ultrasonographic and histological studies supports a multicentric theory for the development of venous disorders due to abnormalities in the composition of the vein wall leading to functional changes. 8-9 However, the investigation of the progression of venous disease is complex and can be measured in a number of different ways. In recent years, there has been a move away from the use of surrogate end points to grade disease severity, such as the presence or absence of reflux, or the use of hemodynamic parameters such as venous refill times. A greater emphasis is now placed on the clinical assessment of disease severity and its function
Lane TRA, Kelleher D, Franklin IJ, et al., 2012, Response, Phlebology, Vol: 27, Pages: 328-328
Harling L, Sepehripour AH, Ashrafian H, et al., 2012, Surgical patch angioplasty of the left main coronary artery., European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Vol: 42, Pages: 719-726
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