Imperial College London
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ProfessorTristanRodriguez

Faculty of Medicine, National Heart & Lung Institute

Professor of Cell and Developmental Biology
 
 
 
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Contact

 

+44 (0)20 7594 5448tristan.rodriguez Website

 
 
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Location

 

331ICTEM buildingHammersmith Campus

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Summary

 

Publications

Citation

BibTex format

@article{di:2016:10.1016/j.devcel.2016.08.012,
author = {di, gregorio A and Bowling, S and Rodriguez, T},
doi = {10.1016/j.devcel.2016.08.012},
journal = {Developmental Cell},
pages = {621--634},
title = {Cell Competition and its role in the regulation of cell fitness from development to cancer},
url = {http://dx.doi.org/10.1016/j.devcel.2016.08.012},
volume = {38},
year = {2016}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Cell competition is a cell fitness-sensing mechanism conserved from insects to mammals that eliminatesthose cells that, although viable, are less fit than their neighbors. An important implication of cell competitionis that cellular fitness is not only a cell-intrinsic property but is also determined relative to the fitness ofneighboring cells: a cell that is of suboptimal fitness in one context may be ‘‘super-fit’’ in the context of adifferent cell population. Here we discuss the mechanisms by which cell competition measures and communicatescell fitness levels and the implications of this mechanism for development, regeneration, and tumorprogression
AU  - di,gregorio A
AU  - Bowling,S
AU  - Rodriguez,T
DO  - 10.1016/j.devcel.2016.08.012
EP  - 634
PY  - 2016///
SN  - 1878-1551
SP  - 621
TI  - Cell Competition and its role in the regulation of cell fitness from development to cancer
T2  - Developmental Cell
UR  - http://dx.doi.org/10.1016/j.devcel.2016.08.012
UR  - http://hdl.handle.net/10044/1/40761
VL  - 38
ER  -
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