Publications
297 results found
Griesenbach U, Jeswiet SB, Larsen MD, et al., 2007, UKCF gene therapy consortium tracking study: Change in sputum properties in response to IV antibiotic, PEDIATRIC PULMONOLOGY, Pages: 229-229, ISSN: 8755-6863
Mitomo K, Griesenbach U, Inoue M, et al., 2007, Potential airway stem/progenitor cell integration after transduction with a lentiviral vector pseudotyped with sendai virus envelope proteins, PEDIATRIC PULMONOLOGY, Pages: 286-286, ISSN: 8755-6863
Holder E, Griesenbach U, Li S, et al., 2006, Intravenously administered oligonucleotides can be delivered to conducting airway epithelium via the bronchial circulation, GENE THERAPY, Vol: 13, Pages: 1628-1638, ISSN: 0969-7128
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- Citations: 6
Mitomo K, Griesenbach U, Inoue M, et al., 2006, Persistent gene expression over the life-time of airway epithelial cells transduced by lentiviral vector pseudotyped with envelope proteins F and HN from Sendai virus, 12th Annual Meeting of the Japan-Society-of-Gene-Therapy, Publisher: JOHN WILEY & SONS LTD, Pages: 1444-1444, ISSN: 1099-498X
Rakonczay Z, Hegyi P, Hasegawa M, et al., 2006, CFTR gene transfer to human cystic fibrosis pancreatic duct cells upregulates apical CL<SUP>-</SUP>/HCO3<SUP>-</SUP> exchange activity, PANCREAS, Vol: 33, Pages: 492-492, ISSN: 0885-3177
Xenariou S, Griesenbach U, Ferrari S, et al., 2006, Using magnetic forces to enhance non-viral gene transfer to airway epithelium <i>in vivo</i>, GENE THERAPY, Vol: 13, Pages: 1545-1552, ISSN: 0969-7128
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- Citations: 69
Griesenbach U, Geddes DM, Alton EWFW, 2006, Gene therapy progress and prospects: cystic fibrosis, GENE THERAPY, Vol: 13, Pages: 1061-1067, ISSN: 0969-7128
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- Citations: 70
Griesenbach U, Brake M, Gardner A, et al., 2006, Proteasome Inhibitors Increase Cationic-Lipid Mediated Gene Transfer in A549 Cells <i>In Vitro</i>, MOLECULAR THERAPY, Vol: 13, Pages: S214-S214, ISSN: 1525-0016
Griesenbach U, McLachlan G, Somerton L, et al., 2006, SeV-Mediated Gene Transfer after Three Re-Administrations in Mice and Sheep, MOLECULAR THERAPY, Vol: 13, Pages: S184-S184, ISSN: 1525-0016
Larsen MDB, Griesenbach U, Goussard S, et al., 2006, Bactofection into Airway Epithelial Cells <i>In Vitro</i> and <i>In Vivo</i> Using a Genetically Modified <i>Escherichia coli</i>, MOLECULAR THERAPY, Vol: 13, Pages: S270-S271, ISSN: 1525-0016
Xenariou S, Liang H-D, Griesenbach U, et al., 2006, Low-Frequency Ultrasound Increases Non-Viral Lung Gene Transfer, MOLECULAR THERAPY, Vol: 13, Pages: S269-S269, ISSN: 1525-0016
Griesenbach U, Mitomo K, Inoue M, et al., 2006, Lentivirus Pseudotyped with Envelope Proteins F and HN from Sendai Virus Transduce Airway Epithelium Efficiency and Persistently, MOLECULAR THERAPY, Vol: 13, Pages: S139-S140, ISSN: 1525-0016
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- Citations: 4
Griesenbach U, Boyton RJ, Somerton L, et al., 2006, Effect of tolerance induction to immunodominant T-cell epitopes of Sendai virus on gene expression following repeat administration to lung, GENE THERAPY, Vol: 13, Pages: 449-456, ISSN: 0969-7128
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- Citations: 16
Mitomo K, Tabata T, Inoue M, et al., 2006, Efficient transduction and prolonged gene expression in murine nasal airways mediated by simian immunodeficiency virus vectors pseudotyped with Sendai virus glycoproteins F and HN, 11th Annual Meeting of the Japan-Society-of-Gene-Therapy, Publisher: JOHN WILEY & SONS LTD, Pages: 389-390, ISSN: 1099-498X
Griesenbach U, Kitson C, Garcia SE, et al., 2006, Inefficient cationic lipid-mediated siRNA and antisense oligonucleotide transfer to airway epithelial cells in vivo, RESPIRATORY RESEARCH, Vol: 7, ISSN: 1465-993X
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- Citations: 54
Hollax EJ, Davies J, Griesenbach U, et al., 2005, Beta-defensin genomic copy number is not a modifier locus for cystic fibrosis, J Negat Results Biomed, Vol: 7
Griesenbach U, Inoue M, Hasegawa M, et al., 2005, Sendai virus for gene therapy and vaccination, CURRENT OPINION IN MOLECULAR THERAPEUTICS, Vol: 7, Pages: 346-352, ISSN: 1464-8431
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- Citations: 26
Radke PW, Griesenbach U, Kivela A, et al., 2005, Vascular oligonucleotide transfer facilitated by a polymer-coated stent, HUMAN GENE THERAPY, Vol: 16, Pages: 734-740, ISSN: 1043-0342
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- Citations: 7
Davies JC, Griesenbach U, Alton E, 2005, Modifier genes in cystic fibrosis, PEDIATRIC PULMONOLOGY, Vol: 39, Pages: 383-391, ISSN: 8755-6863
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- Citations: 43
Griesenbach U, Boyd AC, UK Cystic Fibrosis Gene Therapy Consortium, 2005, Pre-clinical and clinical endpoint assays for cystic fibrosis gene therapy., J Cyst Fibros, Vol: 4, Pages: 89-100, ISSN: 1569-1993
The credibility and hence value of pre-clinical and clinical cystic fibrosis gene therapy studies depend on the assays used to evaluate gene transfer. Awareness of assay suitability, sensitivity and variability is therefore crucial to the design of experimental programmes. Here, we review the assays that are in use to assess the efficacy of gene transfer in pre-clinical and clinical CF gene therapy research, highlight their weaknesses and suggest possible new strategies that may help to overcome current limitations.
Davies JC, Alton E, Griesenbach U, 2005, Cystic fibrosis modifier genes, Journal of the Royal Society of Medicine, Vol: 98, Pages: 47-54
McLachlan G, Griesenbach U, Owaki T, et al., 2004, Recombinant Sendai virus vector to evaluate vector distribution in a large animal model of lung gene transfer, Winter Meeting of the British-Thoracic-Society, Publisher: B M J PUBLISHING GROUP, Pages: 25-25, ISSN: 0040-6376
Griesenbach U, Larsen MDB, Smith SN, et al., 2004, Airway surface liquid height and nasal potential difference measurements in FABP-CF knockout mice: A core facility for screening of non-viral gene transfer agents, Winter Meeting of the British-Thoracic-Society, Publisher: B M J PUBLISHING GROUP, Pages: 27-27, ISSN: 0040-6376
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- Citations: 2
Low T, Lympany PA, Davies JC, et al., 2004, Analysis of the effect of inflammatory gene polymorphisms on clinical phenotype in cystic fibrosis, Winter Meeting of the British-Thoracic-Society, Publisher: B M J PUBLISHING GROUP, Pages: 25-25, ISSN: 0040-6376
Ferrari S, Griesenbach U, Shirai-Iida T, et al., 2004, A defective nontransmissible recombinant Sendai virus mediates efficient gene transfer to airway epithelium in vivo, GENE THERAPY, Vol: 11, Pages: 1659-1664, ISSN: 0969-7128
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- Citations: 44
Griesenbach U, Geddes DM, Alton EWFW, 2004, Advances in cystic fibrosis gene therapy, CURRENT OPINION IN PULMONARY MEDICINE, Vol: 10, Pages: 542-546, ISSN: 1070-5287
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- Citations: 26
Griesenbach U, Geddes DM, Alton EWFW, 2004, Gene therapy for cystic fibrosis: an example for lung gene therapy, GENE THERAPY, Vol: 11, Pages: S43-S50, ISSN: 0969-7128
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- Citations: 44
Radke PW, Kivela A, Vick T, et al., 2004, Efficacy of vascular oligonucleotide transfer using polymer-coated stents, 16th Annual Transcatheter Cardiovascular Therapeutics Symposium, Publisher: EXCERPTA MEDICA INC, Pages: 27E-28E, ISSN: 0002-9149
Munkonge FM, Hillery E, Smith JWS, et al., 2004, Characterisation of cytosolic DNA-binding karyophilic shuttle proteins mediating plasmid DNA import into mammalian cell nuclei, 1st Annual Conference of the British-Society-for-Gene-Therapy, Publisher: JOHN WILEY & SONS LTD, Pages: S8-S8, ISSN: 1099-498X
Griesenbach U, Kitson C, Escudero-Garcia S, et al., 2004, LacZ siRNA and antisense DNA decrease β-galactosidase mRNA but not protein expression in the airways of K18-lacZ transgenic mice, 1st Annual Conference of the British-Society-for-Gene-Therapy, Publisher: JOHN WILEY & SONS LTD, Pages: S21-S22, ISSN: 1099-498X
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