Imperial College London
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DrUlrichHansen

Faculty of Engineering, Department of Mechanical Engineering

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+44 (0)20 7594 7061u.hansen

 
 
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714City and Guilds BuildingSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Zhao:2018:10.1302/2046-3758.78.BJR-2018-0025.R1,
author = {Zhao, S and Arnold, M and Ma, S and Abel, R and Cobb, J and Hansen, U and Boughton, OR},
doi = {10.1302/2046-3758.78.BJR-2018-0025.R1},
journal = {Bone and Joint Research},
pages = {524--538},
title = {Standardising compression testing for measuring the stiffness of human bone: a systematic review},
url = {http://dx.doi.org/10.1302/2046-3758.78.BJR-2018-0025.R1},
volume = {7},
year = {2018}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Objectives: The ability to determine human bone stiffness is of clinical relevance in many fields, including bone quality assessment and orthopaedic prosthesis design. Stiffness can be measured using compression testing; an experimental technique commonly used to test bone specimens in vitro.  This  systematic review  aims to determine how  best  to perform compression testing of human bone. Methods:  A  keyword  search  of  all  English  language  articles  up  until  December  2017  of compression  testing  of bone  was  undertaken  in  Medline,  Embase,  PubMed  and  Scopus databases. Studies using bulk tissue, animal tissue, whole bone or testing techniques other than compression testing were excluded.  Results: 4712 abstracts were retrieved with a total of 177 papers included in the analysis. 20 studies directly analysed the compression testing technique to improve the accuracy of the testing  technique.  Several  influencing  factors  should  be  considered  when  testing  bone samples  in  compression.  These  include  the method  of  data  analysis,  specimen  storage, specimen preparation, testing configuration and loading protocol.  Conclusions: Compression testing is a widely used technique for measuring the stiffness of bone but there is a great deal of inter-study variation in experimental techniques across the literature. Based on best evidence from the literature, suggestions for bone compression testing  are  made  in  this  review,  though  further  studies  are  needed  to  help  establish standardised bone testing techniques to increase the comparability and reliability of bone stiffness studies.
AU  - Zhao,S
AU  - Arnold,M
AU  - Ma,S
AU  - Abel,R
AU  - Cobb,J
AU  - Hansen,U
AU  - Boughton,OR
DO  - 10.1302/2046-3758.78.BJR-2018-0025.R1
EP  - 538
PY  - 2018///
SN  - 2046-3758
SP  - 524
TI  - Standardising compression testing for measuring the stiffness of human bone: a systematic review
T2  - Bone and Joint Research
UR  - http://dx.doi.org/10.1302/2046-3758.78.BJR-2018-0025.R1
UR  - http://hdl.handle.net/10044/1/60456
VL  - 7
ER  -
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