Imperial College London

DrValeriaGarbin

Faculty of EngineeringDepartment of Chemical Engineering

Visiting Professor
 
 
 
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Contact

 

v.garbin

 
 
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Assistant

 

Ms Sevgi Thompson +44 (0)20 7594 1478

 
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Location

 

ACE ExtensionSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Jamburidze:2019:10.1021/acs.langmuir.8b04008,
author = {Jamburidze, A and Huerre, A and Baresch, D and Poulichet, V and De, Corato M and Garbin, V},
doi = {10.1021/acs.langmuir.8b04008},
journal = {Langmuir},
pages = {10087--10096},
title = {Nanoparticle-coated microbubbles for combined ultrasound imaging and drug delivery},
url = {http://dx.doi.org/10.1021/acs.langmuir.8b04008},
volume = {35},
year = {2019}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - Biomedical microbubbles stabilized by a coating of magnetic or drug-containing nanoparticles show great potential for theranostics applications. Nanoparticle-coated microbubbles can be made to be stable, to be echogenic, and to release the cargo of drug-containing nanoparticles with an ultrasound trigger. This Article reviews the design principles of nanoparticle-coated microbubbles for ultrasound imaging and drug delivery, with a particular focus on the physical chemistry of nanoparticle-coated interfaces; the formation, stability, and dynamics of nanoparticle-coated bubbles; and the conditions for controlled nanoparticle release in ultrasound. The emerging understanding of the modes of nanoparticle expulsion and of the transport of expelled material by microbubble-induced flow is paving the way toward more efficient nanoparticle-mediated drug delivery. This Article highlights the knowledge gap that still remains to be addressed before we can control these phenomena.
AU - Jamburidze,A
AU - Huerre,A
AU - Baresch,D
AU - Poulichet,V
AU - De,Corato M
AU - Garbin,V
DO - 10.1021/acs.langmuir.8b04008
EP - 10096
PY - 2019///
SN - 0743-7463
SP - 10087
TI - Nanoparticle-coated microbubbles for combined ultrasound imaging and drug delivery
T2 - Langmuir
UR - http://dx.doi.org/10.1021/acs.langmuir.8b04008
UR - https://pubs.acs.org/doi/10.1021/acs.langmuir.8b04008
UR - http://hdl.handle.net/10044/1/70235
VL - 35
ER -