Summary
Vivianne Goosens is primarily interested in how molecules move from the inside to the outside of bacterial cells. She started her academic career at the University of the Witwatersrand in Johannesburg before moving to Groningen in the Netherlands where she completed her PhD in 2013. Her PhD focused heavily on the Tat secretion pathway in Bacillus subtilis. In 2014 she took a post-doctoral position with Vladimir Pelicic at the CMBI Imperial College where the universal assembly components of Type IV Pili were defined. She started a second post-doctoral position at Imperial College with Tom Ellis where secretion systems in the cellulose producing strain Komagataeibacter rhaeticus are investigated and manipulated. This has lead her interest in protein secretion to be expanded to include polysaccharide secretion.
Publications
Journals
Neef J, Bongiorni C, Schmidt B, et al., 2020, Relative contributions of non-essential Sec pathway components and cell envelope-associated proteases to high-level enzyme secretion by Bacillus subtilis, Microbial Cell Factories, Vol:19
Walker K, Goosens V, Das A, et al., 2019, Engineered cell-to-cell signalling within growing bacterial cellulose pellicles, Microbial Biotechnology, Vol:12, ISSN:1751-7915, Pages:611-619
Berry J, Gurung I, Anonsen JH, et al., 2019, Global biochemical and structural analysis of the type IV pilus from the Gram-positive bacterium Streptococcus sanguinis, Journal of Biological Chemistry, Vol:294, ISSN:0021-9258, Pages:6796-6808
Goosens VJ, Busch A, Georgiadou M, et al., 2017, Reconstitution of a minimal machinery capable of assembling type IV pili, Proceedings of the National Academy of Sciences of the United States of America, Vol:114, ISSN:0027-8424, Pages:E4978-E4986
Neef J, Bongiorni C, Goosens VJ, et al., 2017, Intramembrane protease RasP boosts protein production in Bacillus, Microbial Cell Factories, Vol:16, ISSN:1475-2859