Imperial College London
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DrVictoriaMale

Faculty of Medicine, Department of Metabolism, Digestion and Reproduction

Senior Lecturer in Reproductive Immunology
 
 
 
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Contact

 

v.male

 
 
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Location

 

Chelsea and Westminster HospitalChelsea and Westminster Campus

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Summary

 

Publications

Citation

BibTex format

@article{Dhillon:2021:10.1111/febs.16094,
author = {Dhillon, P and Altmann, D and Male, V},
doi = {10.1111/febs.16094},
journal = {The FEBS Journal},
title = {COVID19 vaccines: what do we know so far?},
url = {http://dx.doi.org/10.1111/febs.16094},
year = {2021}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - When the novel coronavirus was described in late 2019, it could not have been imagined that within a year, more than 100 vaccine candidates would be in preclinical development and several would be in clinical trials and even approved for use. The scale of the COVID-19 outbreak pushed the scientific community, working in collaboration with pharmaceutical companies, public health bodies, policymakers, funders and governments, to develop vaccines against SARS-CoV-2 at record-breaking speed. As well as driving major amendments to the usual timeframe for bringing a vaccine to fruition, the pandemic has accelerated the development of next-generation technologies for vaccinology, giving rise to two frontrunner RNA vaccines. Although none of the critical safety and efficacy steps have been skipped within the compressed schedules, and the technologies underpinning the novel vaccines have been refined by scientists over many years, a significant proportion of the global population is sceptical of the benefits of COVID-19 vaccines and wary of potential risks. In this interview-based article, we give an overview of how the vaccines were developed and how they work to generate a robust immune response against COVID-19, as well as addressing common questions relating to safety and efficacy.
AU  - Dhillon,P
AU  - Altmann,D
AU  - Male,V
DO  - 10.1111/febs.16094
PY  - 2021///
SN  - 1742-464X
TI  - COVID19 vaccines: what do we know so far?
T2  - The FEBS Journal
UR  - http://dx.doi.org/10.1111/febs.16094
UR  - https://febs.onlinelibrary.wiley.com/doi/10.1111/febs.16094
UR  - http://hdl.handle.net/10044/1/90862
ER  -
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