Imperial College London
Dr Vias Markides

DrViasMarkides

Faculty of Medicine, National Heart & Lung Institute

Honorary Clinical Senior Lecturer
 
 
 
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Contact

 

+44 (0)20 7351 8619v.markides

 
 
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Assistant

 

Dr Tom Wong +44 (0)20 7351 8619

 
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Location

 

Chelsea WingRoyal Brompton Campus

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Summary

 

Publications

Citation

BibTex format

@article{Griffiths:2022:10.1111/pace.14449,
author = {Griffiths, S and Behar, JM and Kramer, DB and Debney, MT and Monkhouse, C and Lefas, AY and Lowe, M and Amin, F and Cantor, E and Boyalla, V and Karim, N and Till, J and Markides, V and Clague, JR and Wong, T},
doi = {10.1111/pace.14449},
journal = {Pacing and Clinical Electrophysiology},
pages = {481--490},
title = {The long-term outcomes of cardiac implantable electronic devices implanted via the femoral route},
url = {http://dx.doi.org/10.1111/pace.14449},
volume = {45},
year = {2022}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - BACKGROUND: Conventional superior access for cardiac implantable electronic devices (CIEDs) is not always possible and femoral CIEDs (F-CIED) are an alternative option when leadless systems are not suitable. The long-term outcomes and extraction experiences with F-CIEDs, in particular complex F-CIED (ICD/CRT devices), remain poorly understood. METHODS: Patients referred for F-CIEDs implantation between 2002 and 2019 at two tertiary centers were included. Early complications were defined as ≤30 days following implant and late complications >30 days. RESULTS: Thirty-one patients (66% male; age 56 ± 20 years; 35% [11] patients with congenital heart disease) were implanted with F-CIEDs (10 ICD/CRT and 21 pacemakers). Early complications were observed in 6.5% of patients: two lead displacements. Late complications at 6.8 ± 4.4 years occurred in 29.0% of patients. This was higher with complex F-CIED compared to simple F-CIED (60.0% vs. 14.3%, p = .02). Late complications were predominantly generator site related (n = 8, 25.8%) including seven infections/erosions and one generator migration. Eight femoral generators and 14 leads (median duration in situ seven [range 6-11] years) were extracted without complication. CONCLUSIONS: Procedural success with F-CIEDs is high with clinically acceptable early complication rates. There is a notable risk of late complications, particularly involving the generator site of complex devices following repeat femoral procedures. Extraction of chronic F-CIED in experienced centers is feasible and safe.
AU  - Griffiths,S
AU  - Behar,JM
AU  - Kramer,DB
AU  - Debney,MT
AU  - Monkhouse,C
AU  - Lefas,AY
AU  - Lowe,M
AU  - Amin,F
AU  - Cantor,E
AU  - Boyalla,V
AU  - Karim,N
AU  - Till,J
AU  - Markides,V
AU  - Clague,JR
AU  - Wong,T
DO  - 10.1111/pace.14449
EP  - 490
PY  - 2022///
SN  - 0147-8389
SP  - 481
TI  - The long-term outcomes of cardiac implantable electronic devices implanted via the femoral route
T2  - Pacing and Clinical Electrophysiology
UR  - http://dx.doi.org/10.1111/pace.14449
UR  - https://www.ncbi.nlm.nih.gov/pubmed/35043404
UR  - https://onlinelibrary.wiley.com/doi/10.1111/pace.14449
UR  - http://hdl.handle.net/10044/1/94530
VL  - 45
ER  -
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