Imperial College London

DrVickiMetzis

Faculty of MedicineInstitute of Clinical Sciences

Sir Henry Dale Research Fellow
 
 
 
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Contact

 

v.metzis Website

 
 
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Location

 

4023CRB (Clinical Research Building)Hammersmith Campus

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Summary

 

Summary

Unravelling the molecular mechanisms that impose regional identity in the developing nervous system

As an embryo develops, a wide variety of cell types form along the length of the body. This diversity is dependent on position: some cell types form exclusively in the head, while others form in the trunk. Our ambition is to understand how this organisation is established and maintained during development, by studying the transcriptional control mechanisms that govern cell fate decisions.

Mouse embryo tilescan

Publications

Journals

Gabrysova L, Alvarez-Martinez M, Luisier R, et al., 2019, c-Maf controls immune responses by regulating disease-specific gene networks and repressing IL-2 in CD4(+) T cells (vol 19, pg 497, 2018), Nature Immunology, Vol:20, ISSN:1529-2908, Pages:374-374

Metzis V, Steinhauser S, Pakanavicius E, et al., 2018, Nervous system regionalization entails axial allocation before neural differentiation, Cell, Vol:175, ISSN:0092-8674, Pages:1105-1118.e17

Metzis V, Steinhauser S, Pakanavicius E, et al., 2018, Regionalization of the nervous system requires axial allocation prior to neural lineage commitment, Cell, Vol:175, ISSN:0092-8674, Pages:1105-1118.E17

Gabrysova L, Alvarez-Martinez M, Luisier R, et al., 2018, c-Maf controls immune responses by regulating disease-specific gene networks and repressing IL-2 in CD4(+) T cells, Nature Immunology, Vol:19, ISSN:1529-2908, Pages:497-+

Lu H, Galeano MCR, Ott E, et al., 2017, Mutations in DZIP1L, which encodes a ciliary-transition-zone protein, cause autosomal recessive polycystic kidney disease, Nature Genetics, Vol:49, ISSN:1061-4036, Pages:1025-1034

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