Imperial College London

Dr Vanessa Sancho-Shimizu

Faculty of MedicineDepartment of Infectious Disease

Reader in Human Genetics of Infectious Diseases
 
 
 
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Contact

 

+44 (0)20 7594 3914v.sancho-shimizu

 
 
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Location

 

309Norfolk PlaceSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Ahmad:2019:10.1080/15548627.2019.1580513,
author = {Ahmad, L and Sancho-Shimizu, V},
doi = {10.1080/15548627.2019.1580513},
journal = {Autophagy},
pages = {917--918},
title = {The emerging role of human TBK1 in virus-induced autophagy},
url = {http://dx.doi.org/10.1080/15548627.2019.1580513},
volume = {15},
year = {2019}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - Recent studies have suggested a role for TBK1 in mediating inflammation through macroautophagy/autophagy. While its function in inducing interferon production in response to viral infection has been extensively studied, its role in antiviral autophagy is only beginning to be appreciated. Herein we discuss the role of this multifunctional protein in both antiviral IFN production and in cytoprotective autophagy during HSV-1 infection. Lastly, we highlight the potential implication of TBK1 in the management of inflammation through autophagy, particularly within the central nervous system.
AU - Ahmad,L
AU - Sancho-Shimizu,V
DO - 10.1080/15548627.2019.1580513
EP - 918
PY - 2019///
SN - 1554-8627
SP - 917
TI - The emerging role of human TBK1 in virus-induced autophagy
T2 - Autophagy
UR - http://dx.doi.org/10.1080/15548627.2019.1580513
UR - https://www.tandfonline.com/doi/full/10.1080/15548627.2019.1580513
UR - http://hdl.handle.net/10044/1/67275
VL - 15
ER -