Summary
My research focuses on the genetics of host susceptibility to paediatric infectious diseases in order to understand the host immune response, and to identify immunological biomarkers for disease diagnosis. Diseases of interest include tuberculosis, meningococcal disease and Kawasaki disease.
Publications
Journals
Zandstra J, van de Geer A, Tanck MWT, et al., 2020, Biomarkers for the discrimination of acute kawasaki disease from infections in childhood, Frontiers in Pediatrics, Vol:8, ISSN:2296-2360
Sancho Shimizu V, 2020, A rare mutation in SPLUNC1 underlies meningococcal disease affecting bacterial adherence and invasion, Clinical Infectious Diseases, Vol:70, ISSN:1058-4838, Pages:2045-2053
Borghesi A, Trück J, Asgari S, et al., 2020, Whole-exome sequencing for the identification of rare variants in primary immunodeficiency genes in children with sepsis - a prospective population-based cohort study., Clinical Infectious Diseases, ISSN:1058-4838
Wang X, Nijman R, Camuzeaux S, et al., 2019, Plasma lipid profiles discriminate bacterial from viral infection in febrile children, Scientific Reports, Vol:9, ISSN:2045-2322
Shimizu C, Kim J, Eleftherohorinou H, et al., 2019, HLA-C variants associated with amino acid substitutions in the peptide binding groove influence susceptibility to Kawasaki disease, Human Immunology, Vol:80, ISSN:0198-8859, Pages:731-738