Publications
146 results found
Bernier-Jean A, Wong G, Saglimbene V, et al., 2020, PHYSICAL ACTIVITY AND MORTALITY IN ADULTS UNDERGOING HAEMODIALYSIS: A DIET-HD COHORT STUDY, Publisher: WILEY, Pages: 32-33, ISSN: 1320-5358
Bernier-Jean A, Wong G, Saglimbene V, et al., 2020, DIETARY POTASSIUM INTAKE AND ALL-CAUSE MORTALITY IN ADULTS UNDERGOING HEMODIALYSIS: THE DIET-HD COHORT STUDY, Publisher: WILEY, Pages: 10-10, ISSN: 1320-5358
Mattioli V, Zanolin ME, Cazzoletti L, et al., 2020, Dietary flavonoids and respiratory diseases: a population-based multi-case-control study in Italian adults, Public Health Nutrition, Vol: 23, Pages: 2548-2556, ISSN: 1368-9800
OBJECTIVE: To analyse the associations between chronic respiratory diseases and intakes of total flavonoids and their major subclasses (flavanones, anthocyanins, flavan-3-ols, flavonols, flavones, polymers and proanthocyanidins). DESIGN: Multi-case-control study. SETTING: The analysis was conducted in the frame of the Genes Environment Interaction in Respiratory Diseases (GEIRD) study. The European Prospective Investigation into Cancer and Nutrition FFQ was used to ascertain dietary intake. Multinomial regression models adjusting for age, sex, centre, BMI, smoking habit, alcohol intake, education, total energy intake, vitamin C intake and total fruit intake were used to examine the associations between dietary exposures and the relative risk ratio (RRR) of being a case. PARTICIPANTS: Individuals (n 990) hierarchically defined as follows: cases with asthma (current, n 159; past, n 78), chronic bronchitis (n 47), rhinitis (allergic rhinitis, n 167; non-allergic rhinitis, n 142) and controls (n 97). RESULTS: An increase of 1 sd in flavanones was associated with a reduced risk of non-allergic rhinitis (adjusted RRR = 0·68, 95 % CI 0·47, 0·97); a similar result was found comparing the highest v. lowest quartile of flavanones intake (adjusted RRR = 0·24, 95 % CI 0·10, 0·59). CONCLUSIONS: Flavonoids contained in fruits and vegetables, especially flavanones, might reduce the risk of non-allergic rhinitis. No associations were found between other flavonoids and the considered outcomes.
Ducharme-Smith K, De Castro Mendes F, Villegas R, et al., 2020, Late Breaking Abstract - Ventilatory function and diet quality in US adults - Evidence from the National Health and Nutrition Examination Survey (NHANES), Publisher: EUROPEAN RESPIRATORY SOC JOURNALS LTD, ISSN: 0903-1936
Bédard A, Carsin A-E, Fuertes E, et al., 2020, Physical activity and lung function - cause or consequence?, PLoS One, Vol: 15, ISSN: 1932-6203
Concerns exist that the positive association of physical activity with better lung function, which has been suggested in previous longitudinal studies in smokers, is due to reverse causation. To investigate this, we applied structural equation modeling (SEM), an exploratory approach, and marginal structural modeling (MSM), an approach from the causal inference framework that corrects for reverse causation and time-dependent confounding and estimates causal effects, on data from participants in the European Community Respiratory Health Survey (ECRHS, a multicentre European cohort study initiated in 1991–1993 with ECRHS I, and with two follow-ups: ECRHS II in 1999–2003, and ECRHS III in 2010–2014). 753 subjects who reported current smoking at ECRHS II, with repeated data on lung function at ECRHS I, II and III, physical activity at ECRHS II and III, and potential confounders at ECRHS I and II, were included in the analyses. SEM showed positive associations between physical activity and lung function in both directions. MSM suggested a protective causal effect of physical activity on lung function (overall difference in mean β (95% CI), comparing active versus non-active individuals: 58 mL (21–95) for forced expiratory volume in one second and 83 mL (36–130) for forced vital capacity). Our results suggest bi-directional causation and support a true protective effect of physical activity on lung function in smokers, after accounting for reverse causation and time-dependent confounding.
Mora-Garcia G, Stephany Ruiz-Diaz M, Villegas R, et al., 2020, Changes in diet quality over 10 years of nutrition transition in Colombia: analysis of the 2005 and 2015 nationally representative cross-sectional surveys, INTERNATIONAL JOURNAL OF PUBLIC HEALTH, Vol: 65, Pages: 547-558, ISSN: 1661-8556
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- Citations: 6
Chamitava L, Cazzoletti L, Ferrari M, et al., 2020, Biomarkers of Oxidative Stress and Inflammation in Chronic Airway Diseases, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, Vol: 21
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- Citations: 25
Jarrold K, Helfer B, Eskander M, et al., 2020, Guidance for the conduct and reporting of clinical trials of breast milk substitutes., JAMA Pediatrics, ISSN: 2168-6203
Importance: Breast milk substitutes (BMS) are important nutritional products evaluated in clinical trials. Concerns have been raised about the risk of bias in BMS trials, the reliability of claims that arise from such trials, and the potential for BMS trials to undermine breastfeeding in trial participants. Existing clinical trial guidance does not fully address issues specific to BMS trials. Objectives: To establish new methodological criteria to guide the design, conduct, analysis, and reporting of BMS trials and to support clinical trialists designing and undertaking BMS trials, editors and peer reviewers assessing trial reports for publication, and regulators evaluating the safety, nutritional adequacy, and efficacy of BMS products. Design, Setting, and Participants: A modified Delphi method was conducted, involving 3 rounds of anonymous questionnaires and a face-to-face consensus meeting between January 1 and October 24, 2018. Participants were 23 experts in BMS trials, BMS regulation, trial methods, breastfeeding support, infant feeding research, and medical publishing, and were affiliated with institutions across Europe, North America, and Australasia. Guidance development was supported by an industry consultation, analysis of methodological issues in a sample of published BMS trials, and consultations with BMS trial participants and a research ethics committee. Results: An initial 73 criteria, derived from the literature, were sent to the experts. The final consensus guidance contains 54 essential criteria and 4 recommended criteria. An 18-point checklist summarizes the criteria that are specific to BMS trials. Key themes emphasized in the guidance are research integrity and transparency of reporting, supporting breastfeeding in trial participants, accurate description of trial interventions, and use of valid and meaningful outcome measures. Conclusions and Relevance: Implementation of this guidance should enhance the quality and validity of BMS trials, prot
Mora-García G, Trujillo A, García-Larsen V, 2020, Diet quality, general health and anthropometric outcomes in a Latin American population: evidence from the Colombian National Nutritional Survey (ENSIN) 2010., Public Health Nutr, Pages: 1-8
OBJECTIVE: Colombia is experiencing a nutrition transition, characterised by nutritionally poor diets and an increased prevalence of non-communicable diseases (NCD). We aimed to investigate the association between diet quality and general health outcomes related to the risk of NCD, in a nationally representative sample of Colombian adolescents and adults. DESIGN: Cross-sectional analysis. The Alternative Healthy-Eating Index (AHEI) was derived to calculate diet quality. Adjusted regressions were used to examine the association between AHEI, self-perceived general health status (GHS) and anthropometric variables (i.e. age-specific z-scores for height, and BMI for adolescents; waist circumference and BMI for adults). SETTING: Nationally representative data from the Colombian National Nutrition Survey (ENSIN) 2010. PARTICIPANTS: Adolescents aged 10-17 years (n 6566) and adults aged ≥18 years (n 6750). RESULTS: AHEI scores were similar between adolescents (mean 29·3 ± 7·2) and adults (mean 30·5 ± 7·2). In the whole sample, a better diet quality (higher AHEI score) was associated with worse self-perceived GHS (adjusted (a) β-coefficient: -0·004; P < 0·001) and with a smaller waist circumference ((a) β-coefficient: -0·06; P < 0·01). In adults, a higher AHEI score was negatively associated with BMI ((a) β-coefficient: -0·02; P < 0·05), whilst in adolescents it was associated with a reduced height-for-age z-score ((a) β-coefficient: -0·009; P < 0·001). CONCLUSIONS: A better diet quality was associated with reduced prevalence of predictors of NCD and with some indicators of general health in the Colombian population. In light of the high prevalence of overweight, our findings support the need for public health interventions focused on sustainable positive changes in dietary habits in the general population.
del Giacco S, Couto M, Firinu D, et al., 2020, Management of Intermittent and Persistent Asthma in Adolescent and High School Athletes, JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE, Vol: 8, Pages: 2166-2181, ISSN: 2213-2198
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- Citations: 5
Bjornsdottir E, Lindberg E, Benediktsdottir B, et al., 2020, Are symptoms of insomnia related to respiratory symptoms? Cross-sectional results from 10 European countries and Australia., BMJ Open, Vol: 10, Pages: 1-8, ISSN: 2044-6055
OBJECTIVES: To compare the prevalence of different insomnia subtypes among middle-aged adults from Europe and Australia and to explore the cross-sectional relationship between insomnia subtypes, respiratory symptoms and lung function. DESIGN: Cross-sectional population-based, multicentre cohort study. SETTING: 23 centres in 10 European countries and Australia. METHODS: We included 5800 participants in the third follow-up of the European Community Respiratory Health Survey III (ECRHS III) who answered three questions on insomnia symptoms: difficulties falling asleep (initial insomnia), waking up often during the night (middle insomnia) and waking up early in the morning and not being able to fall back asleep (late insomnia). They also answered questions on smoking, general health and chronic diseases and had the following lung function measurements: forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC) and the FEV1/FVC ratio. Changes in lung function since ECRHS I about 20 years earlier were also analysed. MAIN OUTCOME MEASURES: Prevalence of insomnia subtypes and relationship to respiratory symptoms and function. RESULTS: Overall, middle insomnia (31.2%) was the most common subtype followed by late insomnia (14.2%) and initial insomnia (11.2%). The highest reported prevalence of middle insomnia was found in Iceland (37.2%) and the lowest in Australia (22.7%), while the prevalence of initial and late insomnia was highest in Spain (16.0% and 19.7%, respectively) and lowest in Denmark (4.6% and 9.2%, respectively). All subtypes of insomnia were associated with significantly higher reported prevalence of respiratory symptoms. Only isolated initial insomnia was associated with lower FEV1, whereas no association was found between insomnia and low FEV1/FVC ratio or decline in lung function. CONCLUSION: There is considerable geographical variation in the prevalence of insomnia symptoms. Middle insomnia is most common especially in Iceland. Initial and l
Khalis M, Garcia-Larsen V, Charaka H, et al., 2020, Update of the Moroccan food composition tables: Towards a more reliable tool for nutrition research, Journal of Food Composition and Analysis, Vol: 87, Pages: 103397-103397, ISSN: 0889-1575
de Castro Mendes F, Paciência I, Cavaleiro Rufo J, et al., 2020, The inflammatory potential of diet impacts the association between air pollution and childhood asthma., Pediatric Allergy and Immunology, Vol: 31, Pages: 290-296, ISSN: 0905-6157
BACKGROUND: Inhalation of fine particulate matter (PM) can cause systematic inflammation and oxidative stress, which may further aggravate the development and progression of asthma. Although nutritional intake of fatty acids and antioxidants may attenuate some effects of fine PM, the role of the inflammatory potential of diet has not been addressed. Therefore, we aimed to investigate possible modulatory effects of dietary inflammatory potential on the association of indoor air pollution and childhood asthma-related outcomes. METHODS: In a sample of 501 children (48.1% males, aged 7 to 12 years) from 20 public schools located in Porto, Portugal, we evaluated airway reversibility, exhaled nitric oxide levels, atopy and current respiratory symptoms. Dietary inflammatory index was calculated based on information collected through a reported 24-hour recall questionnaire, and participants were categorized as having an anti-inflammatory or pro-inflammatory diet. Concentrations of indoor PM2.5 and PM10 were measured to assess indoor air quality. Generalized linear mixed models were used to investigate the proportion of effects explained by the exposures to PM2.5 and PM10. RESULTS: After adjustment, the exposure effect of PM2.5 and PM10 levels on children with asthma was higher for those having a pro-inflammatory diet (OR= 1.44, 95% CI: 1.01 to 2.21 and OR=1.29, 95% CI: 1.03 to 1.68, respectively) compared to those having an anti-inflammatory diet. CONCLUSION: These findings suggest that the quality of diet might affect the association of indoor pollution and asthma in children, highlighting the relevance of children's diet as a potential protective factor to pollutants exposure in childhood asthma.
Kim H, Rebholz CM, Garcia-Larsen V, et al., 2020, Operational Differences in Plant-Based Diet Indices Affect the Ability to Detect Associations with Incident Hypertension in Middle-Aged US Adults, JOURNAL OF NUTRITION, Vol: 150, Pages: 842-850, ISSN: 0022-3166
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- Citations: 29
Amaral A, Burney P, Fuertes E, et al., 2020, Body mass index and weight change are associated with adult lung function trajectories: a prospective European survey, Thorax, Vol: 4, Pages: 313-320, ISSN: 0040-6376
Background: Previous studies have reported an association between weight increase and excess lung function decline in young adults followed for short periods. We aimed to estimate lung function trajectories during adulthood according to 20-years weight change profiles, using data from the population-based European Community Respiratory Health Survey (ECRHS).Methods: We included 3,673 participants recruited at age 20-44 years with repeated measurements of weight and lung function (FVC, FEV1) in three study waves (1991-93, 1999-2003, 2010-14) until they were 39-67 years. We classified subjects into weight change profiles according to baseline BMI categories and weight change over 20 years. We estimated trajectories of lung function over time as a function of weight change profiles using population-averaged generalised estimating equations.Results: In individuals with normal BMI, overweight and obesity at baseline, moderate (0.25–1kg/year) and high weight gain (>1kg/year) during follow-up were associated with accelerated FVC and FEV1 declines. Compared to participants with baseline normal BMI and stable weight (±0.25kg/year), obese with high weight gain during follow-up had -1,011 ml [95%CI: -1,259 to -763] lower estimated FVC at 65 years, despite similar estimated FVC levels at 25 years. Obese individuals at baseline who lost weight (<-0.25kg/year) exhibited an attenuation of FVC and FEV1 declines. We found no association between weight change profiles and FEV1/FVC decline. Conclusion: Moderate and high weight gain over 20-years was associated with accelerated lung function decline, while weight loss was related to its attenuation. Control of weight gain is important for maintaining good lung function in adult life.
Saglimbene VM, Wong G, Teixeira-Pinto A, et al., 2020, Dietary Patterns and Mortality in a Multinational Cohort of Adults Receiving Hemodialysis, AMERICAN JOURNAL OF KIDNEY DISEASES, Vol: 75, Pages: 361-372, ISSN: 0272-6386
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- Citations: 11
El Rhazi K, El Kinany K, Garcia-Larsen V, 2020, Socioeconomic factors for the adherence to the Mediterranean diet in North Africa: The shift from 1990 to 2019, The Mediterranean Diet: An Evidence-Based Approach, Pages: 57-65, ISBN: 9780128186497
The North Africa region experiences a drastic shift from a traditional Mediterranean diet to a Westernized diet. Along with these changes the prevalence of chronic diseases increases rapidly. This review reports the various patterns of Mediterranean diets in this region, namely, the change in dietary habits and their relationship with socioeconomic and demographic transitions in this region. The economic, demographic, and social transitions have been accompanied by increasing levels of sedentary lifestyles and obesity and unhealthy diet, which affect all socioeconomic groups but are greater in those with lower resources. Future research in socioeconomic and demographic indicators of nutritional transition in the North African countries is needed to better define these associations.
Mendes FC, Paciencia I, Rufo JC, et al., 2020, The Association Between Vegetable Diversity Intake, Airway Inflammation and Asthma in Portuguese Primary School Children, Virtual International Conference of the American-Thoracic-Society, Publisher: AMER THORACIC SOC, ISSN: 1073-449X
Roberts G, Grimshaw K, Beyer K, et al., 2019, Can dietary strategies in early life prevent childhood food allergy? A report from two iFAAM workshops, Clinical and Experimental Allergy, Vol: 49, Pages: 1567-1577, ISSN: 0954-7894
Food allergy affects a small but significant number of children and adults. Food allergy is responsible for considerable morbidity and is the commonest cause of anaphylaxis in children. One of the aims of the European Union‐funded “Integrated Approaches to Food Allergen and Allergy Risk Management” (iFAAM) project was to improve our understanding of the best way to prevent the development of food allergy. Groups within the project worked on integrating the current prevention evidence base as well as generating new data to move our understanding forward. This paper from the iFAAM project is a unique addition to the literature on this topic as it not only outlines the recently published randomized controlled trials (as have previous reviews) but also summarizes two iFAAM‐associated project workshops. These workshops focused on how we may be able to use dietary strategies in early life to prevent the development of food allergy and summarized the range of opinions amongst experts in this controversial area.
Chamitava L, Zanolin ME, Garcia-Larsen V, et al., 2019, Late Breaking Abstract - Dietary patterns and lung function in a case-control study of asthma in Italian adults, International Congress of the European-Respiratory-Society (ERS), Publisher: EUROPEAN RESPIRATORY SOC JOURNALS LTD, ISSN: 0903-1936
Triebner K, Hustad S, Barrera J, et al., 2019, Late Breaking Abstract - Ultraviolet radiation and lung function in aging women: A European multi-centre study (ECRHS), International Congress of the European-Respiratory-Society (ERS), Publisher: EUROPEAN RESPIRATORY SOC JOURNALS LTD, ISSN: 0903-1936
Bedard A, Accordini S, Carsin A-E, et al., 2019, Is the association between physical activity and lung function due to reverse causation? application of exploratory and causal approaches, International Congress of the European-Respiratory-Society (ERS), Publisher: EUROPEAN RESPIRATORY SOC JOURNALS LTD, ISSN: 0903-1936
Fuertes E, Carsin A-E, Garcia-Larsen V, et al., 2019, The role of C-reactive protein levels on the association of physical activity with lung function in adults, PLoS One, Vol: 14, ISSN: 1932-6203
ObjectiveRegular physical activity may be associated with improved lung function via reduced systemic inflammation, although studies exploring this mechanism are rare. We evaluated the role of C-reactive protein in blood, which is a common marker of systemic inflammation, on the association of physical activity with forced expiratory volume in one second and forced vital capacity.MethodsCross-sectional data on spirometry, C-reactive protein levels and self-reported physical activity (yes/no; ≥2 times and ≥1hr per week of vigorous physical activity) were available in the European Community Respiratory Health Survey (N = 2347 adults, 49.3% male, 28–56 years-old). A subsample was also assessed 10 years later using the International Physical Activity Questionnaire, and tertiles of Metabolic Equivalent of Task—minutes per week spent in vigorous, moderate and walking activities were calculated (N = 671, 49.6% male, 40–67 years-old). Adjusted cross-sectional mixed linear regression models and the “mediate” package in “R” were used to assess the presence of mediation.ResultsDespite positive significant associations between nearly all physical activity metrics with forced expiratory volume in one second and forced vital capacity, there was no evidence that C-reactive protein levels played a role. An influence of C-reactive protein levels was only apparent in the smaller subsample when comparing the medium to low tertiles of moderate activity (mean difference [95% CIs]: 21.1ml [5.2, 41.9] for forced expiratory volume in one second and 17.3ml [2.6, 38.0] for forced vital capacity).ConclusionsIn a population of adults, we found no consistent evidence that the association of physical activity with forced expiratory volume in one second or forced vital capacity is influenced by the level of C-reactive protein in blood.
Kim H, Caulfield LE, Garcia-Larsen V, et al., 2019, Plant-based diets are associated with a lower risk of incident cardiovascular disease, cardiovascular disease mortality, and all-cause mortality in a general population of middle-aged adults, Journal of the American Heart Association, Vol: 8, ISSN: 2047-9980
Background Previous studies have documented the cardiometabolic health benefits of plant-based diets; however, these studies were conducted in selected study populations that had narrow generalizability. Methods and Results We used data from a community-based cohort of middle-aged adults (n=12 168) in the ARIC (Atherosclerosis Risk in Communities) study who were followed up from 1987 through 2016. Participants' diet was classified using 4 diet indexes. In the overall plant-based diet index and provegetarian diet index, higher intakes of all or selected plant foods received higher scores; in the healthy plant-based diet index, higher intakes of only the healthy plant foods received higher scores; in the less healthy plant-based diet index, higher intakes of only the less healthy plant foods received higher scores. In all indexes, higher intakes of animal foods received lower scores. Results from Cox proportional hazards models showed that participants in the highest versus lowest quintile for adherence to overall plant-based diet index or provegetarian diet had a 16%, 31% to 32%, and 18% to 25% lower risk of cardiovascular disease, cardiovascular disease mortality, and all-cause mortality, respectively, after adjusting for important confounders (all P<0.05 for trend). Higher adherence to a healthy plant-based diet index was associated with a 19% and 11% lower risk of cardiovascular disease mortality and all-cause mortality, respectively, but not incident cardiovascular disease (P<0.05 for trend). No associations were observed between the less healthy plant-based diet index and the outcomes. Conclusions Diets higher in plant foods and lower in animal foods were associated with a lower risk of cardiovascular morbidity and mortality in a general population.
Margarida Silva D, Moreira R, Beltrao M, et al., 2019, Exercise and physical activity impact on the allostatic load: Evidence from a two steps clinical trial, Congress of the European-Academy-of-Allergy-and-Clinical-Immunology (EAACI), Publisher: WILEY, Pages: 453-453, ISSN: 0105-4538
Burgess JA, Dharmage SC, Allen K, et al., 2019, Age at introduction to complementary solid food and food allergy and sensitization: a systematic review and meta-analysis, Clinical and Experimental Allergy, Vol: 49, Pages: 754-769, ISSN: 0954-7894
BACKGROUND AND OBJECTIVE: An infant's age at introduction of complementary solids may contribute to food allergy. We aimed to synthesize the literature on the association between age at introduction of complementary solids, excluding milk products, and food allergy and sensitization. DESIGN: We searched the electronic databases PubMed and EMBASE (January 1946-February 2017) using solid food, allergy and sensitization terms. METHODS: Two authors selected papers according to inclusion criteria, identifying 16 cohort studies, 1 case-control study and 8 randomized controlled trials (RCTs). Pooled effects across studies were estimated using random-effects meta-analysis. RESULTS: Cohort studies - Introducing complementary solids at age ≥4 months versus <4 months was not associated with food allergy (OR 1.22; 95%CI, 0.76-1.96) but was associated with food sensitization (OR 1.93; 95%CI 1.57-2.38). First exposure from age 4-6 months versus <4 months was not associated with food allergy (OR 1.01; 95%CI, 0.64-1.60) but was associated with food sensitization (OR 2.46; 95%CI 1.55-3.86). RCTs - Egg exposure from age 4 months was associated with reduced egg allergy (OR 0.63, 95%CI, 0.44-0.90) and sensitization (OR 0.76, 95%CI, 0.51-0.95). Peanut exposure from age 4 months compared to delayed exposure was associated with reduced peanut allergy (OR 0.28, 95%CI 0.14-0.57). CONCLUSIONS: We found no evidence from observational studies that introducing solids before 4 months protected against food allergy, but there was evidence for protection against food sensitization. From RCTs, introducing egg from 4-6 months and peanut from 4-11 months, reduced the risk of egg allergy, peanut allergy and egg sensitization. This article is protected by copyright. All rights reserved.
Saglimbene V, Wong G, Ruospo M, et al., 2019, DIETARY PATTERNS AND MORTALITY IN ADULTS ON HEMODIALYSIS, 56th Congress of the European-Renal-Association (ERA)-European-Dialysis-and-Transplant-Association (EDTA) - Burden, Access and Disparities in Kidney Disease, Publisher: OXFORD UNIV PRESS, ISSN: 0931-0509
Cazzoletti L, Zanolin ME, Spelta F, et al., 2019, Dietary fats, olive oil and respiratory diseases in Italian adults: A population-based study, Clinical and Experimental Allergy, Vol: 49, Pages: 799-807, ISSN: 0954-7894
BACKGROUND: Fat intake has been associated with respiratory diseases, with conflicting results. OBJECTIVE: We studied the association between asthma and rhinitis with dietary fats, and their food sources in an Italian population. METHODS: Clinical and nutritional information was collected for 871 subjects (aged 20-84) from the population-based multi-case-control study Genes Environment Interaction in Respiratory Diseases (GEIRD): 145 with current asthma (CA), 77 with past asthma (PA), 305 with rhinitis and 344 controls. Food intake was collected using the EPIC (European Investigation into Cancer and Nutrition) Food Frequency Questionnaire. The associations between fats and respiratory diseases were estimated by multinomial models. Fats and their dietary sources were analysed both as continuous variables and as quartiles. RESULTS: Monounsaturated fatty acids and oleic acid were associated with a reduced risk of CA in both continuous (RRR = 0.68, 95%CI: 0.48; 0.96; RRR = 0.69; 95%CI: 0.49; 0.97, per 10 g, respectively) and per-quartile analyses (p for trend = 0.028 and 0.024, respectively). Olive oil was associated with a decreased risk of CA (RRR = 0.80; 95%CI: 0.65; 0.98 per 10 g). An increased risk of rhinitis was associated with moderate total fat and SFA intake. CONCLUSIONS: High dietary intakes of oleic acid and of olive oil are associated with a lower risk of asthma but not of rhinitis.
Kim H, Rebholz C, Garcia-Larsen V, et al., 2019, Comparison of plant-based diet indices scoring and risk with hypertension (OR33-06-19), Current Developments in Nutrition, Vol: 3, ISSN: 2475-2991
Objectives: Recently, several distinct diet indices have been developed to characterize adherence to plant-based diets. We deconstructed and compared 6 plant-based diet indices (PDI) in a community-based cohort with respect to their scoring and their associations with incident hypertension. Methods: Using food frequency questionnaire data from middle-aged adults (n = 8041) without hypertension in the Atherosclerosis Risk in Communities (ARIC) Study, we constructed overallPDI, healthyPDI, unhealthyPDI, provegetarian diet index, PDI from Rotterdam Study (PDI-Rotterdam), and comprehensive diet quality index (cDQI). For the overallPDI, provegetarian diet index, and PDI-Rotterdam, higher intakes of all or selected plant foods received higher scores. For the healthyPDI, higher intakes of plant foods identified as healthful received higher scores. For the unhealthyPDI, higher intakes of plant foods identified as unhealthful received higher scores. For the cDQI, higher intakes of healthful plant foods, dairy, and seafood received higher scores, but all other indices scored higher intakes of animal foods uniformly lower. We examined the magnitude of correlations and agreement between all pairs of indices, and assessed whether higher scores on these indices were associated with hypertension using Cox proportional hazard models, adjusting for socio-demographic factors, other dietary factors, and health behaviors. Results: All indices had moderate to strong correlations (r > 0.4) and largely consistent rankings of subjects except for the PDI-Rotterdam and unhealthyPDI. Differences existed in how alcohol, potatoes, poultry, eggs, and dairy were scored. Greater adherence to overallPDI, healthyPDI, provegetarian diet, and cDQI was associated with a 9-26% lower risk of hypertension compared to lesser adherence (all P-trend < 0.05, Table). Greater adherence to the unhealthyPDI was associated with a 12% higher risk (P-trend = 0.03) when c
Kim H, Caulfield LE, Garcia-Larsen V, et al., 2019, Plant-Based Diets and Incident CKD and Kidney Function, CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, Vol: 14, Pages: 682-691, ISSN: 1555-9041
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- Citations: 97
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