Imperial College London
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DrVanessaGarcia Larsen

Faculty of Medicine, National Heart & Lung Institute

Honorary Lecturer
 
 
 
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Contact

 

+44 (0)20 7594 7945vgla

 
 
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Location

 

61Emmanuel Kaye BuildingRoyal Brompton Campus

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Summary

 

Publications

Citation

BibTex format

@article{Mattioli:2020:10.1017/S1368980019003562,
author = {Mattioli, V and Zanolin, ME and Cazzoletti, L and Bono, R and Cerveri, I and Ferrari, M and Pirina, P and Garcia-Larsen, V},
doi = {10.1017/S1368980019003562},
journal = {Public Health Nutrition},
pages = {2548--2556},
title = {Dietary flavonoids and respiratory diseases: a population-based multi-case-control study in Italian adults},
url = {http://dx.doi.org/10.1017/S1368980019003562},
volume = {23},
year = {2020}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - OBJECTIVE: To analyse the associations between chronic respiratory diseases and intakes of total flavonoids and their major subclasses (flavanones, anthocyanins, flavan-3-ols, flavonols, flavones, polymers and proanthocyanidins). DESIGN: Multi-case-control study. SETTING: The analysis was conducted in the frame of the Genes Environment Interaction in Respiratory Diseases (GEIRD) study. The European Prospective Investigation into Cancer and Nutrition FFQ was used to ascertain dietary intake. Multinomial regression models adjusting for age, sex, centre, BMI, smoking habit, alcohol intake, education, total energy intake, vitamin C intake and total fruit intake were used to examine the associations between dietary exposures and the relative risk ratio (RRR) of being a case. PARTICIPANTS: Individuals (n 990) hierarchically defined as follows: cases with asthma (current, n 159; past, n 78), chronic bronchitis (n 47), rhinitis (allergic rhinitis, n 167; non-allergic rhinitis, n 142) and controls (n 97). RESULTS: An increase of 1 sd in flavanones was associated with a reduced risk of non-allergic rhinitis (adjusted RRR = 0·68, 95 % CI 0·47, 0·97); a similar result was found comparing the highest v. lowest quartile of flavanones intake (adjusted RRR = 0·24, 95 % CI 0·10, 0·59). CONCLUSIONS: Flavonoids contained in fruits and vegetables, especially flavanones, might reduce the risk of non-allergic rhinitis. No associations were found between other flavonoids and the considered outcomes.
AU  - Mattioli,V
AU  - Zanolin,ME
AU  - Cazzoletti,L
AU  - Bono,R
AU  - Cerveri,I
AU  - Ferrari,M
AU  - Pirina,P
AU  - Garcia-Larsen,V
DO  - 10.1017/S1368980019003562
EP  - 2556
PY  - 2020///
SN  - 1368-9800
SP  - 2548
TI  - Dietary flavonoids and respiratory diseases: a population-based multi-case-control study in Italian adults
T2  - Public Health Nutrition
UR  - http://dx.doi.org/10.1017/S1368980019003562
UR  - https://www.ncbi.nlm.nih.gov/pubmed/31996276
UR  - https://www.cambridge.org/core/journals/public-health-nutrition/article/dietary-flavonoids-and-respiratory-diseases-a-populationbased-multicasecontrol-study-in-italian-adults/25478B9CDCA1F56F712CA8672598501B
UR  - http://hdl.handle.net/10044/1/77059
VL  - 23
ER  -
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