Imperial College London
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ProfessorWendyBarclay

Faculty of Medicine, Department of Infectious Disease

Action Medical Research Chair Virology. Head of Department
 
 
 
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Contact

 

+44 (0)20 7594 5035w.barclay

 
 
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Location

 

416Medical SchoolSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Whitaker:2022:10.1038/s41467-022-34244-2,
author = {Whitaker, M and Elliott, J and Bodinier, B and Barclay, W and Ward, H and Cooke, G and Donnelly, C and Chadeau, M and Elliott, P},
doi = {10.1038/s41467-022-34244-2},
journal = {Nature Communications},
pages = {1--10},
title = {Variant-specific symptoms of COVID-19 in a study of 1,542,510 adults in England},
url = {http://dx.doi.org/10.1038/s41467-022-34244-2},
volume = {13},
year = {2022}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Infection with SARS-CoV-2 virus is associated with a wide range of symptoms. The REal-time Assessment of Community Transmission -1 (REACT-1) study monitored the spread and clinical manifestation of SARS-CoV-2 among random samples of the population in England from 1 May 2020 to 31 March 2022. We show changing symptom profiles associated with the different variants over that period, with lower reporting of loss of sense of smell or taste for Omicron compared to previous variants, and higher reporting of cold-like and influenza-like symptoms, controlling for vaccination status. Contrary to the perception that recent variants have become successively milder, Omicron BA.2 was associated with reporting more symptoms, with greater disruption to daily activities, than BA.1. With restrictions lifted and routine testing limited in many countries, monitoring the changing symptom profiles associated with SARS-CoV-2 infection and effects on daily activities will become increasingly important.
AU  - Whitaker,M
AU  - Elliott,J
AU  - Bodinier,B
AU  - Barclay,W
AU  - Ward,H
AU  - Cooke,G
AU  - Donnelly,C
AU  - Chadeau,M
AU  - Elliott,P
DO  - 10.1038/s41467-022-34244-2
EP  - 10
PY  - 2022///
SN  - 2041-1723
SP  - 1
TI  - Variant-specific symptoms of COVID-19 in a study of 1,542,510 adults in England
T2  - Nature Communications
UR  - http://dx.doi.org/10.1038/s41467-022-34244-2
UR  - https://www.nature.com/articles/s41467-022-34244-2
UR  - http://hdl.handle.net/10044/1/100312
VL  - 13
ER  -
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