Imperial College London
Alternate

ProfessorWaljitDhillo

Faculty of Medicine, Department of Metabolism, Digestion and Reproduction

Professor of Endocrinology & Metabolism
 
 
 
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Contact

 

+44 (0)20 7594 3487w.dhillo Website

 
 
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Assistant

 

Ms Suzanne Wheeler +44 (0)20 7594 3487

 
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Location

 

6N6ECommonwealth BuildingHammersmith Campus

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Summary

 

Publications

Citation

BibTex format

@article{Mills:2022:10.1111/jne.13201,
author = {Mills, EG and Dhillo, WS},
doi = {10.1111/jne.13201},
journal = {Journal of Neuroendocrinology},
title = {Invited review: Translating kisspeptin and neurokinin B biology into new therapies for reproductive health},
url = {http://dx.doi.org/10.1111/jne.13201},
volume = {34},
year = {2022}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - The reproductive neuropeptide kisspeptin has emerged as the master regulator of mammalian reproduction due to its key roles in the initiation of puberty and the control of fertility. Alongside the tachykinin neurokinin B and the endogenous opioid dynorphin, these peptides are central to the hormonal control of reproduction. Building on the expanding body of experimental animal models, interest has flourished with human studies revealing that kisspeptin administration stimulates physiological reproductive hormone secretion in both healthy men and women, as well as patients with common reproductive disorders. In addition, emerging therapeutic roles based on neurokinin B for the management of menopausal flushing, endometriosis and uterine fibroids are increasingly recognised. In this review, we focus on kisspeptin and neurokinin B and their potential application as novel clinical strategies for the management of reproductive disorders.
AU  - Mills,EG
AU  - Dhillo,WS
DO  - 10.1111/jne.13201
PY  - 2022///
SN  - 0953-8194
TI  - Invited review: Translating kisspeptin and neurokinin B biology into new therapies for reproductive health
T2  - Journal of Neuroendocrinology
UR  - http://dx.doi.org/10.1111/jne.13201
UR  - https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000870036700001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=a2bf6146997ec60c407a63945d4e92bb
UR  - https://onlinelibrary.wiley.com/doi/10.1111/jne.13201
UR  - http://hdl.handle.net/10044/1/107030
VL  - 34
ER  -
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