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@article{Lo:2023:10.1007/978-1-0716-2695-5_20,
author = {Lo, Y and Liang, S and Dhillo, WS and Cass, AEG and Tanner, JA},
doi = {10.1007/978-1-0716-2695-5_20},
journal = {Methods Mol Biol},
pages = {271--280},
title = {Robotic APTamer-Enabled Electrochemical Reader (RAPTER) System for Automated Aptamer-Mediated Electrochemical Analysis.},
url = {http://dx.doi.org/10.1007/978-1-0716-2695-5_20},
volume = {2570},
year = {2023}
}

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TY  - JOUR
AB  - Electrochemical aptamer-based (E-AB) sensors using conformational change-induced electron transfer kinetics are sensitive, reagent-less, and cost-effective tools for molecular sensing. Current advances in this technology can allow continuous drug pharmacokinetic monitoring in living animals (Dauphin-Ducharme et al., ACS Sens 4(10):2832-2837, 2019; Idili et al., Chem Sci 10(35):8164-8170, 2019), as well as automated analysis of hormone pulsatility (Liang et al., Nat Commun 10(1):852, 2019). In this chapter, we provide the methodology for an automated E-AB conformational change-based robotic sensing platform. By using an open-source programmable robotic system, this method can be adapted to a wide range of experimental scenarios.
AU  - Lo,Y
AU  - Liang,S
AU  - Dhillo,WS
AU  - Cass,AEG
AU  - Tanner,JA
DO  - 10.1007/978-1-0716-2695-5_20
EP  - 280
PY  - 2023///
SP  - 271
TI  - Robotic APTamer-Enabled Electrochemical Reader (RAPTER) System for Automated Aptamer-Mediated Electrochemical Analysis.
T2  - Methods Mol Biol
UR  - http://dx.doi.org/10.1007/978-1-0716-2695-5_20
UR  - https://www.ncbi.nlm.nih.gov/pubmed/36156789
VL  - 2570
ER  -

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