Imperial College London

DrWing MayKong

Faculty of MedicineDepartment of Metabolism, Digestion and Reproduction

Honorary Senior Lecturer in Endocrinology and Ethics
 
 
 
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Contact

 

+44 (0)20 7594 0881w.kong Website

 
 
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Location

 

325Reynolds BuildingCharing Cross Campus

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Summary

 

Publications

Publication Type
Year
to

33 results found

Gillon R, Boyd K, Brazier M, Campbell A, Goddard A, Kong WM, Limerick S, Lock S, Montgomery Jet al., 2019, Guest editorial: a tribute to the Very Reverend Edward Shotter (FCMME), JOURNAL OF MEDICAL ETHICS, Vol: 45, Pages: 629-630, ISSN: 0306-6800

Journal article

Kerr M, Barron E, Chadwick P, Evans T, Kong WM, Rayman G, SuttonSmith M, Todd G, Young B, Jeffcoate WJet al., 2019, The cost of diabetic foot ulcers and amputations to the National Health Service in England, Diabetic Medicine, Vol: 36, Pages: 995-1002, ISSN: 0742-3071

<jats:title>Abstract</jats:title><jats:sec><jats:title>Aim</jats:title><jats:p>To estimate the healthcare costs of diabetic foot disease in England.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>Patient‐level data sets at a national and local level, and evidence from clinical studies, were used to estimate the annual cost of health care for foot ulceration and amputation in people with diabetes in England in 2014–2015.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>The cost of health care for ulceration and amputation in diabetes in 2014–2015 is estimated at between £837 million and £962 million; 0.8% to 0.9% of the National Health Service (<jats:styled-content style="fixed-case">NHS</jats:styled-content>) budget for England. More than 90% of expenditure was related to ulceration, and 60% was for care in community, outpatient and primary settings. For inpatients, multiple regression analysis suggested that ulceration was associated with a length of stay 8.04 days longer (95% confidence interval 7.65 to 8.42) than that for diabetes admissions without ulceration.</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>Diabetic foot care accounts for a substantial proportion of healthcare expenditure in England, more than the combined cost of breast, prostate and lung cancers. Much of this expenditure arises through prolonged and severe ulceration. If the <jats:styled-content style="fixed-case">NHS</jats:styled-content> were to reduce the prevalence of diabetic foot ulcers in England by one‐third, the gross annual saving would be more than £250 million. Diabetic foot ulceration is a large and growing problem globally, and it is likely that there is potential to improve outcomes and reduce expen

Journal article

Kong WM, Knight S, 2017, Bridging the education-action gap: a near-peer case-based undergraduate ethics teaching programme, JOURNAL OF MEDICAL ETHICS, Vol: 43, Pages: 692-696, ISSN: 0306-6800

Journal article

Kong WM, 2015, What is good medical ethics? A clinician's perspective, JOURNAL OF MEDICAL ETHICS, Vol: 41, Pages: 79-82, ISSN: 0306-6800

Journal article

Kong WM, Vernon B, 2013, Harnessing the LMG legacy: the IME's vision for the future, JOURNAL OF MEDICAL ETHICS, Vol: 39, Pages: 669-671, ISSN: 0306-6800

Journal article

Parekh R, Beaconsfield T, Kong WM, 2012, A woman with neck pain and shortness of breath, BRITISH MEDICAL JOURNAL, Vol: 345, ISSN: 1756-1833

Journal article

Kong WM, Vernon B, Boyd K, Gillon R, Farsides B, Stirrat Get al., 2011, Include medical ethics in the Research Excellence Framework, BMJ: British Medical Journal, Vol: 343, Pages: d3968-d3968

Journal article

Preston-Shoot M, McKimm J, Kong WM, Smith Set al., 2011, Readiness for legally literate medical practice? Student perceptions of their undergraduate medico-legal education., Journal of Medical Ethics, Vol: 37, Pages: 616-622

Journal article

Kong WM, Richardson J, 2010, Patient Autonomy and Patient Ethics, Publisher: Department of Health Foundation eLearning project

Working paper

Kong WM, Richardson J, 2010, Vulnerable Patients and Patient Abuse, Publisher: Department of health Foundation elearning project

Working paper

Kong WM, Richardson J, 2010, Confidentiality and Privacy, Publisher: Department of health Foundatuion eLearning Project

Working paper

Smith KL, Gardiner JV, Ward HL, Kong WM, Murphy KG, Martin NM, Ghatei MA, Bloom SRet al., 2008, Overexpression of CART in the PVN increases food intake and weight gain in rats, OBESITY, Vol: 16, Pages: 2239-2244, ISSN: 1930-7381

Journal article

Raby A, Car J, Kong WM, 2008, Type 2 diabetes: follow up., London J Prim Care (Abingdon), Vol: 1, Pages: 10-11, ISSN: 1757-1472

A 41 year old accountant recently registered with your practice. His registration health check indicates: BMI 31, BP 150/95, urine 1 + of glucose, no protein, smoker of 15 cigarettes daily. He has had diabetes for seven years and is taking Metformin 500 mg four times daily. It has been over a year since he last saw a doctor and he has now come to see you to obtain a prescription for medication.

Journal article

Martin NM, Small CJ, Lee JL, Ellis S, Dhillo WS, Smith KL, Kong WM, Frost GS, Bloom SRet al., 2007, Low-dose oral tri-iodothyronine does not directly increase food intake in man, DIABETES OBESITY & METABOLISM, Vol: 9, Pages: 435-437, ISSN: 1462-8902

Journal article

Bishop CL, Ramalho M, Nadkarni N, Kong WM, Higgins CF, Krauzewicz Net al., 2006, Role for centromeric heterochrornatin and PML nuclear bodies in the cellular response to foreign DNA, MOLECULAR AND CELLULAR BIOLOGY, Vol: 26, Pages: 2583-2594, ISSN: 0270-7306

Journal article

Bewick GA, Dhillo WS, Darch SJ, Murphy KG, Gardiner JV, Jethwa PH, Kong WM, Ghatei MA, Bloom SRet al., 2005, Hypothalamic cocaine- and amphetamine-regulated transcript (CART) and agouti-related protein (AgRP) neurons coexpress the NOP1 receptor and nociceptin alters CART and AgRP release, ENDOCRINOLOGY, Vol: 146, Pages: 3526-3534, ISSN: 0013-7227

Journal article

Kong WM, 2005, Legitimate requests and indecent proposals: matters of justice in the ethical assessment of phase I trials involving competent patients., Journal of Medical Ethics, Vol: 31, Pages: 205-208

Journal article

Gardiner JV, Kong WM, Ward H, Murphy KG, Dhillo WS, Bloom SRet al., 2005, AAV mediated expression of anti-sense neuropeptide Y cRNA in the arcuate nucleus of rats results in decreased weight gain and food intake, Biochemical and Biophysical research Communications, Vol: 327, Pages: 1088-1093

Journal article

Kong WM, 2004, The Regulation of Gene Therapy Research In Competent Adult Patients, Today And Tomorrow: Implications Of EU Directive 2001/20/EC, Medical Law Review, Vol: 12, Pages: 164-180, ISSN: 0967-0742

Journal article

Stanley SA, Murphy KG, Bewick GA, Kong WM, Opacka-Juffry J, Gardiner JV, Ghatei MA, Small CJ, Bloom SRet al., 2004, Regulation of rat pituitary cocaine- and amphetamine-regulated transcript (CART) by CRH and glucocorticoids, American Journal of Physiology Endocrinology and Metabolism, Vol: 287, Pages: E583-E590

Journal article

Kong WM, Martin N, Smith K, Gardiner J, Small C, Connoley I, Stephens D, Gjatei M, Bloom Set al., 2004, Triiodothyronine stimulates food intake via the hypothalamic ventromedial nucleus independent of changes in energy expenditure, Endocrinology, Vol: 145, Pages: 5252-5258

Journal article

le Roux CW, Chapman GA, Kong WM, Dhillo WS, Jones J, Alaghband-Zadeh Jet al., 2003, Free cortisol index is better than serum total cortisol in determining hypothalamic-pituitary-adrenal status in patients undergoing surgery, JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, Vol: 88, Pages: 2045-2048, ISSN: 0021-972X

Journal article

Kong WM, Stanley S, Gardiner J, Abbott C, Murphy K, Seth A, Connoley I, Ghatei M, Stephens D, Bloom Set al., 2003, A role for arcuate cocaine and amphetamine-regulated transcript in hyperphagia, thermogenesis, and cold adaptation., The FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol: 17, Pages: 1688-1690

We have recently shown that injection of the hypothalamic peptide cocaine and amphetamine regulated transcript (CART) into discrete hypothalamic nuclei stimulates food intake. This stimulation was particularly marked in the arcuate nucleus. Here we show that twice daily intra-arcuate injection of 0.2 nmole CART peptide for 7 days was associated with a 60% higher daytime food intake, an 85% higher thermogenic response to the beta3 agonist BRL 35135, and a 60% increase in brown adipose tissue UCP-1 mRNA. In a separate study, using stereotactically targeted gene transfer, a CART transgene was delivered by using polyethylenimine to the arcuate nucleus of adult rats. Food intake was increased significantly during ad libitum feeding and following periods of food withdrawal and food restriction in CART over-expressing animals. CART over-expressing animals lost 12% more weight than controls following a 24-h fast. Brown adipose tissue uncoupling protein-1 (UCP-1) mRNA levels (collected Day 25) were 80% higher in CART over-expressing animals. Finally, by using quantitative in situ hybridization, we found that chronic cold exposure (20 days at 4oC) increased arcuate nucleus CART mRNA by 124%. Together with the orexigenic and thermogenic effects of CART, this finding suggests a role for arcuate nucleus CART in cold adaptation.

Journal article

Kong WM, Stanley S, Gardiner J, Abbott C, Murphy K, Seth A, Connoley I, Ghatei M, Stephens D, Bloom Set al., 2003, A role for arcuate cocaine and amphetamine-regulated transcript in hyperphagia, thermogenesis, and cold adaptation., FASEB J, Vol: 15, Pages: 1688-1690

Journal article

Ward H, Gardiner J, Kong WM, Murphy K, Bloom Set al., 2003, Distribution of fluorescence following injection of recombinant adeno-associated virus encoding green fluorescent protein into the paraventricular nucleus, Neuroendocrinology, Vol: 77, Pages: 100-104

Journal article

le Roux CW, Sivakumaran S, Alaghband-Zadeh J, Dhillo W, Kong WM, Wheeler MJet al., 2002, Free cortisol index as a surrogate marker for serum free cortisol, ANNALS OF CLINICAL BIOCHEMISTRY, Vol: 39, Pages: 406-408, ISSN: 0004-5632

Journal article

Kong WM, Sheikh MH, Lumb PJ, Freedman DB, Crook M, Dore CJ, Finer Net al., 2002, A 6-month Randomized trial of thyroxine treatment in women with mild subclinical hypothyroidism, AMERICAN JOURNAL OF MEDICINE, Vol: 112, Pages: 348-354, ISSN: 0002-9343

Journal article

Dhillo WS, Kong WM, Le Roux CW, Alaghband-Zadeh J, Jones J, Carter G, Mendoza N, Meeran K, O'Shea Det al., 2002, Cortisol-binding globulin is important in the interpretation of dynamic tests of the hypothalamic-pituitary-adrenal axis, EUROPEAN JOURNAL OF ENDOCRINOLOGY, Vol: 146, Pages: 231-235, ISSN: 0804-4643

Journal article

le Roux CW, Sivakumarn J, Alaghband-Zadeh J, Dhillo W, Kong WM, Wheeler MJet al., 2002, Free cortisol index as a surrogate marker for serum free cortisol., Annals of Clinical Biochemistry, Vol: 39, Pages: 406-406

Journal article

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