Imperial College London

Prof. William Wisden F. Med. Sci.

Faculty of Natural SciencesDepartment of Life Sciences

Chair in Molecular Neuroscience



+44 (0)20 7594 9744w.wisden Website CV




401BSir Ernst Chain BuildingSouth Kensington Campus





Research interests and techniques

    AAV infected subicular neurons, Dr A. Zecharia
  • Neuroscience: molecular biology; transgenics, neuroanatomy, physiology, behaviour. 
  • Mechanisms of sleep
  • Hypothalamic function: the regulation of neurons which make histamine: the tuberomammillary nucleus and sleep regulation
  • other neuromodulators which regulate sleep



1986 BA,  Zoology - Natural Sciences, University of Cambridge
1989 PhD Molecular Neuroscience, University of Cambridge (with Stephen P. Hunt).

Posts held:

1990-1992 EMBO Long-term Fellowship, ZMBH, University of Heidelberg (with Peter H. Seeburg)
1993-2001 Group Leader, MRC LMB, Cambridge
2001-2005 Group Leader, IZN, University of Heidelberg
2005-2009 Professor & Chair of Neuroscience, Head of Neurobiology programme, Institute of Medical Sciences, University of Aberdeen

2009- Professor of Molecular Neuroscience



How to find us: click here for a map  - we are on the 4th floor  of the Sir Ernst Chain Building (marked "30" on the map)

Imperial College''s location in London:

 Royal Albert Hall - next to Imperial College

 Albert Hall - view from Imperial






Scammell TE, Jackson AC, Franks NP, et al., 2018, Histamine: Neural circuits and new medications., Sleep

Paul EJ, Kalk E, Tossell K, et al., 2018, nNOS-Expressing Neurons in the Ventral Tegmental Area and Substantia Nigra Pars Compacta., Eneuro, Vol:5

Harding EC, Yu X, Miao A, et al., 2018, A Neuronal Hub Binding Sleep Initiation and Body Cooling in Response to a Warm External Stimulus, Current Biology, Vol:28, ISSN:0960-9822, Pages:2263-+

Brickley SG, Franks NP, Wisden W, 2018, Modulation of GABA<inf>A</inf> receptor function and sleep, Current Opinion in Physiology, Vol:2, ISSN:2468-8681, Pages:51-57

Gelegen C, Miracca G, Ran MZ, et al., 2018, Excitatory Pathways from the Lateral Habenula Enable Propofol-Induced Sedation, Current Biology, Vol:28, ISSN:0960-9822, Pages:580-+

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