Imperial College London

Prof. William Wisden F. Med. Sci.

Faculty of Natural SciencesDepartment of Life Sciences

Chair in Molecular Neuroscience
 
 
 
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Contact

 

+44 (0)20 7594 9744w.wisden Website CV

 
 
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Location

 

401BSir Ernst Chain BuildingSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Herb:1997:10.1006/mcne.1996.0594,
author = {Herb, A and Wisden, W and Catania, MV and Marechal, D and Dresse, A and Seeburg, PH},
doi = {10.1006/mcne.1996.0594},
journal = {Mol Cell Neurosc},
pages = {367--374},
title = {Prominent dendritic localization in forebrain neurons of a novel mRNA and its product, dendrin},
url = {http://dx.doi.org/10.1006/mcne.1996.0594},
volume = {8},
year = {1997}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - A recently cloned rat brain cDNA derives from a novel gene, termed dendrin (DEN), expressed exclusively in forebrain structures, particularly in neocortex, olfactory bulb, hippocampus, caudate-putamen, and limbic system. In these structures, the cognate mRNA is present in neuronal cell bodies and their dendrites, whereas near exclusive dendritic localization is observed for the polypeptide product. In the hippocamus, DEN mRNA is highly expressed in the cell laminae and dendritic layers of the dentate gyrus and CA1 field, but expression is markedly reduced in the CA3 and CA4 areas. The predicted primary structure of the hydrophilic, highly basic 653-amino-acid polypeptide does not suggest a function. The restricted expression and dendritic location are compatible with a role for DEN in synaptic plasticity of central neocortical forebrain neurons.
AU - Herb,A
AU - Wisden,W
AU - Catania,MV
AU - Marechal,D
AU - Dresse,A
AU - Seeburg,PH
DO - 10.1006/mcne.1996.0594
EP - 374
PY - 1997///
SN - 1044-7431
SP - 367
TI - Prominent dendritic localization in forebrain neurons of a novel mRNA and its product, dendrin
T2 - Mol Cell Neurosc
UR - http://dx.doi.org/10.1006/mcne.1996.0594
VL - 8
ER -