Publications
219 results found
Linden A-M, Schmitt U, Leppa E, et al., 2011, Ro 15-4513 antagonizes alcohol-induced sedation in mice through αβγ2-type GABA<sub>A</sub> receptors, FRONTIERS IN NEUROSCIENCE, Vol: 5, ISSN: 1662-453X
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- Citations: 21
Muhammad S, Aller MI, Maser-Gluth C, et al., 2010, EXPRESSION OF THE KCNK3 POTASSIUM CHANNEL GENE LESSENS THE INJURY FROM CEREBRAL ISCHEMIA, MOST LIKELY BY A GENERAL INFLUENCE ON BLOOD PRESSURE, NEUROSCIENCE, Vol: 167, Pages: 758-764, ISSN: 0306-4522
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- Citations: 24
Donner BC, Schullenberg M, Decking U, et al., 2010, CARDIAC PHENOTYPING THE TASK-1 DEFICIENT MOUSE, Publisher: ELSEVIER SCIENCE INC, ISSN: 0735-1097
Heimann D, Bandulik S, Penton D, et al., 2010, The role of TASK potassium channels in the control of aldosterone secretion, ENDOCRINE JOURNAL, Vol: 57, Pages: S276-S276, ISSN: 0918-8959
Wisden W, 2010, Cre-ating ways to serotonin, FRONTIERS IN NEUROSCIENCE, Vol: 4, ISSN: 1662-453X
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- Citations: 2
Wisden W, Meier JC, 2010, Genetic techniques and circuit analysis., Front Mol Neurosci, Vol: 3, ISSN: 1662-5099
Pang DSJ, Robledo CJ, Carr DR, et al., 2009, An unexpected role for TASK-3 potassium channels in network oscillations with implications for sleep mechanisms and anesthetic action, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 106, Pages: 17546-17551, ISSN: 0027-8424
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- Citations: 64
Donner B, Schullenberg M, Huning A, et al., 2009, Cardiac phenotyping the TASK-1 deficient mouse, CLIN RES CARDIOL, Vol: 98, Pages: 589-589, ISSN: 1861-0684
Wulff P, Schonewille M, Renzi M, et al., 2009, Synaptic inhibition of Purkinje cells mediates consolidation of vestibulo-cerebellar motor learning, NATURE NEUROSCIENCE, Vol: 12, Pages: 1042-U118, ISSN: 1097-6256
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- Citations: 203
Wulff P, Ponomarenko AA, Bartos M, et al., 2009, Hippocampal theta rhythm and its coupling with gamma oscillations require fast inhibition onto parvalbumin-positive interneurons, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 106, Pages: 3561-3566, ISSN: 0027-8424
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- Citations: 265
Murray A, Black C, Cheyne L, et al., 2009, P.1.22 Selective modulation of parvalbumin GABAergic interneuron function in-vivo in mice, European Neuropsychopharmacology, Vol: 19, Pages: S20-S21, ISSN: 0924-977X
Wisden W, 2009, Engineering receptor subtypes as tools in neuropsychopharmacology, European-College-of-Neuropsychopharmacology Workshop on Neuropsychopharmacology for Young Scientists in Europe, Publisher: ELSEVIER SCIENCE BV, Pages: S2-S3, ISSN: 0924-977X
Wisden W, 2009, S.1.02 Engineering receptor subtypes as tools in neuropsychopharmacology, European Neuropsychopharmacology, Vol: 19, Pages: S2-S3, ISSN: 0924-977X
Murray A, Black C, Cheyne L, et al., 2009, Selective modulation of parvalbumin GABAergic interneuron function in-vivo in mice, European-College-of-Neuropsychopharmacology Workshop on Neuropsychopharmacology for Young Scientists in Europe, Publisher: ELSEVIER SCIENCE BV, Pages: S20-S21, ISSN: 0924-977X
Gajendran N, Kapfhammer JP, Lain E, et al., 2009, Neuregulin Signaling Is Dispensable for NMDA- and GABA<sub>A</sub>-Receptor Expression in the Cerebellum <i>In Vivo</i>, JOURNAL OF NEUROSCIENCE, Vol: 29, Pages: 2404-2413, ISSN: 0270-6474
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- Citations: 20
Goetz T, Wulff P, Wisden W, 2009, GABA<inf>A</inf> Receptors: Molecular Biology, Cell Biology, and Pharmacology, Pages: 463-470
Γ-Aminobutyric acid A (GABAA) receptors are the principal means of delivering fast (millisecond) inhibition to neurons in the vertebrate central nervous system. The receptors are ligand-gated chloride channels in the nicotinic acetylcholine receptor superfamily. On the binding of two GABA molecules, a conformational change occurs, and Cl? moves into the cell, producing an inhibitory hyperpolarization. Drugs acting at the GABAA receptor are used widely in medicine, such as for the induction and maintenance of general anesthesia or to treat anxiety disorders, states of agitation, epilepsy, or sleep disorders. There is scope to develop these drugs further so that they produce fewer side effects. © 2009 Elsevier Ltd All rights reserved.
Wisden W, Murray AJ, McClure C, et al., 2009, Studying cerebellar circuits by remote control of selected neuronal types with GABA<sub>A</sub> receptors, FRONTIERS IN MOLECULAR NEUROSCIENCE, Vol: 2, ISSN: 1662-5099
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- Citations: 19
Peterschmitt Y, Weger S, Plauth A, et al., 2008, Establishing a new mouse model for investigating the function of amygdala neurons in anxiety, BMC Pharmacology, Vol: 8
Linden A-M, Aller MI, Leppa E, et al., 2008, K<SUP>+</SUP> channel TASK-1 knockout mice show enhanced sensitivities to ataxic and hypnotic effects of GABA<sub>A</sub> receptor ligands, JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, Vol: 327, Pages: 277-286, ISSN: 0022-3565
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- Citations: 23
Trapp S, Aller MI, Wisden W, et al., 2008, A role for TASK-1 (KCNK3) channels in the chemosensory control of breathing, JOURNAL OF NEUROSCIENCE, Vol: 28, Pages: 8844-8850, ISSN: 0270-6474
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- Citations: 108
Aller MI, Wisden W, 2008, Changes in expression of some two-pore domain potassium channel genes (<i>KCNK</i>) in selected brain regions of developing mice, NEUROSCIENCE, Vol: 151, Pages: 1154-1172, ISSN: 0306-4522
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- Citations: 61
Heitzmann D, Derand R, Jungbauer S, et al., 2008, Invalidation of TASK1 potassium channels disrupts adrenal gland zonation and mineralocorticoid homeostasis, EMBO JOURNAL, Vol: 27, Pages: 179-187, ISSN: 0261-4189
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- Citations: 154
Wisden W, 2008, Commissioned meeting report: Glutamate and GABAA receptors – a BNA conference, Durham, UK, 9th April 2008., The Investigational drugs database Alerts (IDdb Alerts)
Linden A-M, Sandu C, Aller MI, et al., 2007, TASK-3 knockout mice exhibit exaggerated nocturnal activity, impairments in cognitive functions, and reduced sensitivity to inhalation Anesthetics, JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, Vol: 323, Pages: 924-934, ISSN: 0022-3565
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- Citations: 79
Brickley SG, Aller MI, Sandu C, et al., 2007, TASK-3 two-pore domain potassium channels enable sustained high-frequency firing in cerebellar granule neurons, JOURNAL OF NEUROSCIENCE, Vol: 27, Pages: 9329-9340, ISSN: 0270-6474
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- Citations: 92
Wulff P, Goetz T, Leppa E, et al., 2007, From synapse to behavior: rapid modulation of defined neuronal types with engineered GABAA receptors, NATURE NEUROSCIENCE, Vol: 10, Pages: 923-929, ISSN: 1097-6256
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- Citations: 91
Korpi ER, Debus F, Linden A-M, et al., 2007, Does ethanol act preferentially via selected brain GABA<sub>A</sub> receptor subtypes?: the current evidence is ambiguous, ALCOHOL, Vol: 41, Pages: 163-176, ISSN: 0741-8329
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- Citations: 59
Wulff P, Goetz T, Leppä E, et al., 2007, From synapse to behavior: Rapid modulation of defined neuronal types with engineered GABA<inf>A</inf> receptors, Neuroforum, Vol: 13, Pages: 134-136, ISSN: 0947-0875
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- Citations: 1
Summerfield A, Wisden W, 2007, Fig.1 Cerebros Warhol, Paisajes neuronales. Homenaje a Santiago Ramon y Cajal, Editors: DeFelipe, Markram, Wagensberg, Pages: 195-195, ISBN: 9788400085339
Osten P, Wisden W, Sprengel R, 2007, Molecular mechanisms of synaptic function in the hippocampus: neurotransmitter exocytosis, glutamatergic, GABAergic and cholinergic transmission., The hippocampus book, Editors: Andersen, Morris, Amaral, Bliss, O'Keefe, Publisher: Oxford University Press, USA, Pages: 243-295, ISBN: 9780195100273
The Hippocampus Book is destined to take a central place on every neuroscientist'sbookshelf.
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