Imperial College London
Portrait Picture

ProfessorXiaodongZhang

Faculty of Medicine, Department of Infectious Disease

Professor of Macromolecular Structure and Function
 
 
 
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Contact

 

+44 (0)20 7594 3151xiaodong.zhang Website

 
 
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Assistant

 

Miss Kelly Butler +44 (0)20 7594 2763

 
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Location

 

104Sir Alexander Fleming BuildingSouth Kensington Campus

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Summary

 

Publications

Publication Type
Year
to

151 results found

Alguel Y, Meng C, Teran W, Krell T, Ramos JL, Gallegos M-T, Zhang Xet al., 2007, Crystal structures of multidrug binding protein TtgR in complex with antibiotics and plant antimicrobials, JOURNAL OF MOLECULAR BIOLOGY, Vol: 369, Pages: 829-840, ISSN: 0022-2836

Journal article

Schumacher J, Joly N, Rappas M, Bradley D, Wigneshweraraj SR, Zhang X, Buck Met al., 2007, Sensor I threonine of the AAA plus ATPase transcriptional activator PspF is involved in coupling nucleoticle triphosphate hydrolysis to the restructuring of σ<SUP>54</SUP>-RNA polymerase, JOURNAL OF BIOLOGICAL CHEMISTRY, Vol: 282, Pages: 9825-9833

Journal article

Rappas M, Bose D, Zhang X, 2007, Bacterial enhancer-binding proteins:: unlocking σ<SUP>54</SUP>-dependent gene transcription, CURRENT OPINION IN STRUCTURAL BIOLOGY, Vol: 17, Pages: 110-116, ISSN: 0959-440X

Journal article

Pye VE, Beuron F, Keetch CA, McKeown C, Robinson CV, Meyer HH, Zhang X, Freemont PSet al., 2007, Structural insights into the p97-Ufd1-NpI4 complex, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 104, Pages: 467-472, ISSN: 0027-8424

Journal article

Uchiyama K, Totsukawa G, Puhka M, Kaneko Y, Jokitalo E, Dreveny I, Beuron F, Zhang X, Freemont P, Kondo Het al., 2006, P37 is a p97 adaptor required for Golgi and ER biogenesis in interphase and at the end of mitosis, DEVELOPMENTAL CELL, Vol: 11, Pages: 803-816, ISSN: 1534-5807

Journal article

Buck M, Bose D, Burrows P, Cannon W, Joly N, Pape T, Rappas M, Schumacher J, Wigneshweraraj S, Zhang Xet al., 2006, A second paradigm for gene activation in bacteria, BIOCHEMICAL SOCIETY TRANSACTIONS, Vol: 34, Pages: 1067-1071, ISSN: 0300-5127

Journal article

Schumacher J, Joly N, Rappas M, Zhang X, Buck Met al., 2006, Structures and organisation of AAA plus enhancer binding proteins in transcriptional activation, JOURNAL OF STRUCTURAL BIOLOGY, Vol: 156, Pages: 190-199, ISSN: 1047-8477

Journal article

Pye VE, Dreveny I, Briggs LC, Sands C, Beuron F, Zhang X, Freemont PSet al., 2006, Going through the motions: The ATPase cycle of p97, JOURNAL OF STRUCTURAL BIOLOGY, Vol: 156, Pages: 12-28, ISSN: 1047-8477

Journal article

Suno R, Niwa H, Tsuchiya D, Zhang X, Yoshida M, Morikawa Ket al., 2006, Structure of the whole cytosolic region of ATP-dependent protease FtsH, MOLECULAR CELL, Vol: 22, Pages: 575-585, ISSN: 1097-2765

Journal article

Rappas M, Schumacher J, Niwa H, Buck M, Zhang XDet al., 2006, Structural basis of the nucleotide driven conformational changes in the AAA<SUP>+</SUP> domain of transcription activator PspF, JOURNAL OF MOLECULAR BIOLOGY, Vol: 357, Pages: 481-492, ISSN: 0022-2836

Journal article

Huo YX, Tian ZX, Rappas M, Wen J, Chen YC, You CH, Zhang X, Buck M, Wang YP, Kolb Aet al., 2006, Protein-induced DNA bending clarifies the architectural organization of the σ<SUP>54</SUP>-dependent <i>glnA</i>p2 promoter, MOLECULAR MICROBIOLOGY, Vol: 59, Pages: 168-180, ISSN: 0950-382X

Journal article

Beuron F, Dreveny I, Yuan X, Pye VE, McKeown C, Briggs LC, Cliff MJ, Kaneko Y, Wallis R, Isaacson RL, Ladbury JE, Matthews SJ, Kondo H, Zhang X, Freemont PSet al., 2006, Conformational changes in the AAA ATPase p97-p47 adaptor complex, Vol: 25, Pages: 1967-1976, ISSN: 0261-4189

Journal article

Wang Q, Song CC, Irizarry L, Dai RM, Zhang XD, Li CCHet al., 2005, Multifunctional roles of the conserved arg residues in the second region of homology of p97/valosin-containing protein, JOURNAL OF BIOLOGICAL CHEMISTRY, Vol: 280, Pages: 40515-40523, ISSN: 0021-9258

Journal article

Ramos JL, Martínez-Bueno M, Molina-Henares AJ, Terán W, Watanabe K, Zhang XD, Gallegos MT, Brennan R, Tobes Ret al., 2005, The TetR family of transcriptional repressors, MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS, Vol: 69, Pages: 326-+, ISSN: 1092-2172

Journal article

Guazzaroni MAE, Krell T, Felipe A, Ruiz R, Meng CX, Zhang XD, Gallegos MT, Ramos JLet al., 2005, The multidrug efflux regulator TtgV recognizes a wide range of structurally different effectors in solution and complexed with target DNA, JOURNAL OF BIOLOGICAL CHEMISTRY, Vol: 280, Pages: 20887-20893

Journal article

Rappas M, Schumacher J, Beuron F, Niwa H, Bordes P, Wigneshweraraj S, Keetch CA, Robinson CV, Buck M, Zhang XDet al., 2005, Structural insights into the activity of enhancer-binding proteins, SCIENCE, Vol: 307, Pages: 1972-1975, ISSN: 0036-8075

Journal article

Wigneshweplaraj SR, Burrows PC, Bordes P, Schumacher J, Rappas M, Finn RD, Cannon WV, Zhang X, Buck Met al., 2005, The second paradigm for activation of transcription, PROGRESS IN NUCLEIC ACID RESEARCH AND MOLECULAR BIOLOGY, VOL 79, Vol: 79, Pages: 339-369, ISSN: 0079-6603

Journal article

Dreveny I, Pye VE, Beuron F, Briggs LC, Isaacson RL, Matthews SJ, McKeown C, Yuan X, Zhang X, Freemont PSet al., 2004, P97 and close encounters of every kind: a brief review, BIOCHEMICAL SOCIETY TRANSACTIONS, Vol: 32, Pages: 715-720, ISSN: 0300-5127

Journal article

Schumacher J, Zhang XD, Jones S, Bordes P, Buck Met al., 2004, ATP-dependent transcriptional activation by bacterial PspF AAA plus protein, JOURNAL OF MOLECULAR BIOLOGY, Vol: 338, Pages: 863-875, ISSN: 0022-2836

Journal article

Guazzaroni ME, Terán W, Zhang XD, Gallegos MT, Ramos JLet al., 2004, TtgV bound to a complex operator site represses transcription of the promoter for the multidrug and solvent extrusion TtgGHI pump, JOURNAL OF BACTERIOLOGY, Vol: 186, Pages: 2921-2927, ISSN: 0021-9193

Journal article

Yuan XM, Simpson P, Mckeown C, Kondo H, Uchiyama K, Wallis R, Dreveny I, Keetch C, Zhang XD, Robinson C, Freemont P, Matthews Set al., 2004, Structure, dynamics and interactions of p47, a major adaptor of the AAA ATPase, p97, EMBO JOURNAL, Vol: 23, Pages: 1463-1473, ISSN: 0261-4189

Journal article

Smith GR, Contreras-Moreira B, Zhang XD, Bates PAet al., 2004, A link between sequence conservation and domain motion within the AAA plus family, 5th International Conference on AAA(plus) Proteins, Publisher: ACADEMIC PRESS INC ELSEVIER SCIENCE, Pages: 189-204, ISSN: 1047-8477

Conference paper

Rappas M, Niwa H, Zhang XD, 2004, Mechanisms of ATPases - A multi-disciplinary approach, CURRENT PROTEIN & PEPTIDE SCIENCE, Vol: 5, Pages: 89-105, ISSN: 1389-2037

Journal article

Bordes P, Wigneshweraraj SR, Zhang XD, Buck Met al., 2004, σ<SUP>54</SUP>-dependent transcription activator phage shock protein F of <i>Escherichia coli</i>:: a fragmentation approach to identify sequences that contribute to self-association, BIOCHEMICAL JOURNAL, Vol: 378, Pages: 735-744, ISSN: 0264-6021

Journal article

Dreveny I, Kondo H, Uchiyama K, Shaw A, Zhang XD, Freemont PSet al., 2004, Structural basis of the interaction between the AAA ATPase p97/VCP and its adaptor protein p47, EMBO JOURNAL, Vol: 23, Pages: 1030-1039, ISSN: 0261-4189

Journal article

Yuan XM, Simpson P, Kondo H, Mckeown C, Dreveny I, Zhang XD, Freemont PS, Matthews Set al., 2004, Letter to the Editor: Complete backbone resonance assignments of p47: The 41kDa adaptor protein of the AAA ATPase p97, JOURNAL OF BIOMOLECULAR NMR, Vol: 28, Pages: 309-310, ISSN: 0925-2738

Journal article

Huyton T, Pye VE, Briggs LC, Flynn TC, Beuron F, Kondo H, Ma JP, Zhang XD, Freemont PSet al., 2003, The crystal structure of murine p97/VCP at 3.6 Å, JOURNAL OF STRUCTURAL BIOLOGY, Vol: 144, Pages: 337-348, ISSN: 1047-8477

Journal article

Uchiyama K, Jokitalo E, Lindman M, Jackman M, Kano F, Murata M, Zhang XD, Kondo Het al., 2003, The localization and phosphorylation of p47 are important for Golgi disassembly-assembly during the cell cycle, JOURNAL OF CELL BIOLOGY, Vol: 161, Pages: 1067-1079, ISSN: 0021-9525

Journal article

Beuron F, Flynn TC, Ma JP, Kondo H, Zhang XD, Freemont PSet al., 2003, Motions and negative cooperativity between p97 domains revealed by cryo-electron microscopy and quantised elastic deformational model, JOURNAL OF MOLECULAR BIOLOGY, Vol: 327, Pages: 619-629, ISSN: 0022-2836

Journal article

Bordes P, Wigneshweraraj SR, Schumacher J, Zhang XD, Chaney M, Buck Met al., 2003, The ATP hydrolyzing transcription activator phage shock protein F of <i>Escherichia coli</i>:: Identifying a surface that binds σ<SUP>54</SUP>, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 100, Pages: 2278-2283, ISSN: 0027-8424

Journal article

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