Summary
Yan Liu is a chemist by training. Following a B.Sc. degree in chemistry at Peking University, China, she undertook her Ph.D. in organic chemistry at the University of Bristol under the guidance of Professor Tim Gallagher.
Yan joined the Glycosciences Laboratory directed by Professor Ten Feizi at Imperial College in 2005 as one of the postdoc researchers funded by the UK Glycoarray Consortium. Having initially focused on the development of novel glycan probes for microarrays, her work has been extended to microarray analyses of different proteins/pathogens of biomedical interest during the follow-on EPSRC Translational grant,
Since 2013, Yan is the Microarray Project Leader of the Wellcome Trust-funded Carbohydrate Microarray Facility. In April 2018, Yan became a co-investigator in the 5-year Imperial College-March of Dimes (MOD) European Preterm Birth Research Centre programme. Her research is focused on understanding the interactions of host glycans of the female reproductive tract with commensal and pathogenic microbiota during pregnancy and their impact on preterm birth.
Yan is a lecturer in Glycosciences since March 2019. She is the lead applicant of the recently awarded Wellcome Trust Biomedical Resource Grant (4-year, £1.34M), which will provide support for the Carbohydrate Microarray Facility as a cross-faculty collaboration between the Department of Metabolism, Digestion and Reproduction and the Department of Chemistry.
Publications
Journals
Clark LC, Atkin KE, Whelan F, et al., 2023, Staphylococcal Periscope proteins Aap, SasG, and Pls project noncanonical legume-like lectin adhesin domains from the bacterial surface, Journal of Biological Chemistry, Vol:299, ISSN:0021-9258, Pages:1-11
Sorin MN, Di Maio A, Silva LM, et al., 2023, Structural and functional analysis of natural capsid variants reveals sialic-acid independent entry of BK polyomavirus, Cell Reports, ISSN:2211-1247
Shahin M, Sheppard D, Raynaud C, et al., 2023, Characterization of a glycan-binding complex of minor pilins completes theanalysis of Streptococcus sanguinis type 4 pili subunits, Proceedings of the National Academy of Sciences of Usa, Vol:120, ISSN:0027-8424
Akune Y, Arpinar S, Silva LM, et al., 2022, CarbArrayART-An update on the software tool for carbohydrate microarray data, storage, processing, presentation and reporting, Glycobiology, Vol:30, ISSN:0959-6658, Pages:1031-1031
Correia VG, Trovao F, Pinheiro BA, et al., 2021, Mapping Molecular Recognition of beta 1,3-1,4-Glucans by a Surface Glycan-Binding Protein from the Human Gut Symbiont Bacteroides ovatus, Microbiology Spectrum, Vol:9, ISSN:2165-0497