Imperial College London
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DR YUTONG SAMUEL CAI

Faculty of Medicine, School of Public Health

Honorary Research Fellow
 
 
 
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Contact

 

yutong.cai

 
 
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Location

 

155Wright Fleming WingSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Song:2020:10.1016/S2214-109X(20)30117-0,
author = {Song, P and Fang, Z and Wang, H and Cai, Y and Rahimi, K and Zhu, Y and Fowkes, FGR and Fowkes, FJI and Rudan, I},
doi = {10.1016/S2214-109X(20)30117-0},
journal = {The Lancet Global Health},
pages = {e721--e729},
title = {Global and regional prevalence, burden and risk factors for carotid atherosclerosis: a systematic review and modelling analysis},
url = {http://dx.doi.org/10.1016/S2214-109X(20)30117-0},
volume = {8},
year = {2020}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - BackgroundEstimation of the epidemiological burden of carotid atherosclerosis can serve as a basis for prevention and management of cardiovascular disease. We aimed to provide the first estimation on the prevalence, number of cases, and risk factors for carotid atherosclerosis in the general population globally and regionally.MethodsIn this systematic review, meta-analysis, and modelling study, we searched PubMed, MEDLINE, Embase, Global Health, and China National Knowledge Infrastructure for articles published from database inception until May 7, 2019, with no language restrictions, for population-based studies that quantified prevalence of carotid atherosclerosis by means of increased carotid intima-media thickness, carotid plaque, and carotid stenosis. Studies were eligible if they included bilaterally scanned carotid arteries using ultrasonography and defined increased carotid intima-media thickness as a thickness of 1·0 mm or more, carotid plaque as a focal carotid intima-media thickness of 1·5 mm or more encroaching into the lumen or at least 0·5 mm or 50% compared with the surrounding carotid intima-media thickness values, and carotid stenosis as 50% or more stenosis. Studies were excluded if the sample was not representative of the general population. We also included studies identified in our previous systematic review and meta-analysis of the prevalence of carotid atherosclerosis in China. We estimated age-specific and sex-specific prevalences of increased carotid intima-media thickness, carotid plaque, and carotid stenosis. We used UN population data to generate the number of people affected in 2000, 2015, and 2020. We did random-effects meta-analyses to assess the effects of risk factors for increased carotid intima-media thickness and carotid plaque. We derived regional numbers of people living with increased carotid intima-media thickness and carotid plaque in 2015 using a risk factors-based model by WHO region. All analyses were d
AU  - Song,P
AU  - Fang,Z
AU  - Wang,H
AU  - Cai,Y
AU  - Rahimi,K
AU  - Zhu,Y
AU  - Fowkes,FGR
AU  - Fowkes,FJI
AU  - Rudan,I
DO  - 10.1016/S2214-109X(20)30117-0
EP  - 729
PY  - 2020///
SN  - 2214-109X
SP  - 721
TI  - Global and regional prevalence, burden and risk factors for carotid atherosclerosis: a systematic review and modelling analysis
T2  - The Lancet Global Health
UR  - http://dx.doi.org/10.1016/S2214-109X(20)30117-0
UR  - http://hdl.handle.net/10044/1/78967
VL  - 8
ER  -
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