Imperial College London
Alternate

Dr Melody Zhifang Ni

Faculty of Medicine, Department of Surgery & Cancer

Senior Research Fellow
 
 
 
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Contact

 

+44 (0)20 3312 7657z.ni

 
 
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Location

 

Queen Elizabeth the Queen Mother Wing (QEQM)St Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Huddy:2019:10.1515/cclm-2018-1089,
author = {Huddy, JR and Ni, M and Misra, S and Mavroveli, S and Barlow, J and Hanna, GB},
doi = {10.1515/cclm-2018-1089},
journal = {Clinical Chemistry and Laboratory Medicine},
pages = {845--855},
title = {Development of the Point-of-Care Key Evidence Tool (POCKET): a checklist for multi-dimensional evidence generation in point-of-care tests},
url = {http://dx.doi.org/10.1515/cclm-2018-1089},
volume = {57},
year = {2019}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - BackgroundThis study aimed to develop the Point-of-Care Key Evidence Tool (POCKET); a multi-dimensional checklist to guide the evaluation of point-of-care tests (POCTs) incorporating validity, utility, usability, cost-effectiveness and patient experience. The motivation for this was to improve the efficiency of evidence generation in POCTs and reduce the lead-time for the adoption of novel POCTs.MethodsA mixed qualitative and quantitative approach was applied. Following a literature search, a three round Delphi process was undertaken incorporating a semi-structured interview study and two questionnaire rounds. Participants included clinicians, laboratory personnel, commissioners, regulators (including members of National Institute for Health and Care Excellence [NICE] committees), patients, industry representatives and methodologists. Qualitative data were analysed based on grounded theory. The final tool was revised at an expert stakeholder workshop.ResultsForty-three participants were interviewed within the semi-structured interview study, 32 participated in the questionnaire rounds and nine stakeholders attended the expert workshop. The final version of the POCKET checklist contains 65 different evidence requirements grouped into seven themes. Face validity, content validity and usability has been demonstrated. There exists a shortfall in the evidence that industry and research methodologists believe should be generated regarding POCTs and what is actually required by policy and decision makers to promote implementation into current healthcare pathways.ConclusionsThis study has led to the development of POCKET, a checklist for evidence generation and synthesis in POCTs. This aims to guide industry and researchers to the evidence that is required by decision makers to facilitate POCT adoption so that the benefits they can bring to patients can be effectively realised.
AU  - Huddy,JR
AU  - Ni,M
AU  - Misra,S
AU  - Mavroveli,S
AU  - Barlow,J
AU  - Hanna,GB
DO  - 10.1515/cclm-2018-1089
EP  - 855
PY  - 2019///
SN  - 1434-6621
SP  - 845
TI  - Development of the Point-of-Care Key Evidence Tool (POCKET): a checklist for multi-dimensional evidence generation in point-of-care tests
T2  - Clinical Chemistry and Laboratory Medicine
UR  - http://dx.doi.org/10.1515/cclm-2018-1089
UR  - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000466846200021&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR  - http://hdl.handle.net/10044/1/71967
VL  - 57
ER  -
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