Imperial College London


Faculty of MedicineDepartment of Metabolism, Digestion and Reproduction

Senior Lecturer in Biomedical Mass Spectrometry







E305Burlington DanesHammersmith Campus





I joined the Section of Biomolecular Medicine at Imperial, in 2019, as a Lecturer in Lipid Metabolism & Signalling. Prior to this, I carried out my PhD at the University of Oxford and held post-doctoral appointments at the London School of Hygiene and Tropical Medicine (2013-2014) and the University of Cambridge (2014-2019).

My research interests lie at the intersection of mass spectrometry imaging, lipid metabolism and spatial systems biology, and fall broadly into the following themes:

  • Spatial (dis)organisation in liver injury, repair and cancer
  • Mapping cancer metabolism in time and space
  • Tools and method development for spatial systems biology

Selected Publications

Journal Articles

Paterson HAB, Yu S, Artigas N, et al., 2022, Liver RBFOX2 regulates cholesterol homeostasis via Scarb1 alternative splicing in mice, Nature Metabolism, Vol:4, ISSN:2522-5812, Pages:1812-1829

Belenguer G, Mastrogiovanni G, Pacini C, et al., 2022, RNF43/ZNRF3 loss predisposes to hepatocellular-carcinoma by impairing liver regeneration and altering the liver lipid metabolic ground-state., Nature Communications, Vol:13, ISSN:2041-1723, Pages:1-18

Newberry E, Hall ZL, Yan X, et al., 2021, Liver specific deletion of mouse Tm6sf2 promotes steatosis, fibrosis and hepatocellular cancer, Hepatology, Vol:74, ISSN:0270-9139, Pages:1203-1219

Azzu V, Vacca M, Kamzolas I, et al., 2021, Suppression of insulin-induced gene 1 (INSIG1) function promotes hepatic lipid remodelling and restrains NASH progression, Molecular Metabolism, Vol:48, ISSN:2212-8778, Pages:1-10

Hall Z, Chiarugi D, Charidemou E, et al., 2021, Lipid remodelling in hepatocyte proliferation and hepatocellular carcinoma, Hepatology, Vol:73, ISSN:0270-9139, Pages:1028-1044

Bianchi A, Marchetti L, Hall Z, et al., 2021, Moderate exercise inhibits age-related inflammation, liver steatosis, senescence, and tumorigenesis., Journal of Immunology, Vol:206, ISSN:0022-1767, Pages:904-916

Hall Z, Wilson CH, Burkhart DL, et al., 2020, Myc linked to dysregulation of cholesterol transport and storage in non-small cell lung cancer., Journal of Lipid Research, Vol:61, ISSN:0022-2275, Pages:1390-1399

Bond NJ, Koulman A, Griffin JL, et al., 2017, massPix: an R package for annotation and interpretation of mass spectrometry imaging data for lipidomics, Metabolomics, Vol:13, ISSN:1573-3882

Hall Z, Chu Y, Griffin JL, 2017, Liquid extraction surface analysis mass spectrometry method for identifying the presence and severity of nonalcoholic fatty liver disease, Analytical Chemistry, Vol:89, ISSN:0003-2700, Pages:5161-5170

Hall Z, Bond NJ, Ashmore T, et al., 2017, Lipid zonation and phospholipid remodeling in nonalcoholic fatty liver disease, Hepatology, Vol:65, ISSN:0270-9139, Pages:1165-1180

Hall Z, Ament Z, Wilson CH, et al., 2016, Myc expression drives aberrant lipid metabolism in lung cancer, Cancer Research, Vol:76, ISSN:1538-7445, Pages:4608-4618

More Publications