DrZoeHall

Faculty of Medicine, Department of Metabolism, Digestion and Reproduction

Lecturer in Lipid Metabolism and Signalling (Non-Clinical)

Contact

Location

E305Burlington DanesHammersmith Campus

Summary

I joined the section of Biomolecular Medicine at Imperial, in 2019, as a Lecturer in Lipid Metabolism & Signalling. Prior to this, I carried out my PhD at the University of Oxford and held post-doctoral appointments at the London School of Hygiene and Tropical Medicine (2013-2014) and the University of Cambridge (2014-2019).

My research interests lie at the intersection of mass spectrometry imaging, lipid metabolism and spatial systems biology, and fall broadly into the following themes:

Spatial (dis)organisation in liver injury, repair and cancer
Mapping cancer metabolism in time and space
Tools and method development for spatial systems biology

Selected Publications

Journal Articles

Paterson HAB, Yu S, Artigas N, et al.Paterson HAB, Yu S, Artigas N, Prado MA, Haberman N, Wang Y-F, Jobbins AM, Pahita E, Mokochinski J, Hall Z, Guerin M, Paulo JA, Ng SS, Villarroya F, Rashid ST, Le Goff W, Lenhard B, Cebola I, Finley D, Gygi SP, Sibley CR, Vernia S close, 2022, Liver RBFOX2 regulates cholesterol homeostasis via Scarb1 alternative splicing in mice, Nature Metabolism, Vol:4, ISSN:2522-5812, Pages:1812-1829

Belenguer G, Mastrogiovanni G, Pacini C, et al.Belenguer G, Mastrogiovanni G, Pacini C, Hall Z, Dowbaj AM, Arnes-Benito R, Sljukic A, Prior N, Kakava S, Bradshaw CR, Davies S, Vacca M, Saeb-Parsy K, Koo B-K, Huch M close, 2022, RNF43/ZNRF3 loss predisposes to hepatocellular-carcinoma by impairing liver regeneration and altering the liver lipid metabolic ground-state., Nature Communications, Vol:13, ISSN:2041-1723, Pages:1-18

Newberry E, Hall ZL, Yan X, et al.Newberry E, Hall ZL, Yan X, Molitor E, Bayguinov P, Strout G, Fitzpatrick J, Brunt E, Griffin J, Davidson N close, 2021, Liver specific deletion of mouse Tm6sf2 promotes steatosis, fibrosis and hepatocellular cancer, Hepatology, Vol:74, ISSN:0270-9139, Pages:1203-1219

Azzu V, Vacca M, Kamzolas I, et al.Azzu V, Vacca M, Kamzolas I, Hall Z, Leslie J, Carobbio S, Virtue S, Davies SE, Lukasik A, Dale M, Bohlooly-Y M, Acharjee A, Lindén D, Bidault G, Petsalaki E, Griffin JL, Oakley F, Allison MED, Vidal-Puig A close, 2021, Suppression of insulin-induced gene 1 (INSIG1) function promotes hepatic lipid remodelling and restrains NASH progression, Molecular Metabolism, Vol:48, ISSN:2212-8778, Pages:1-10

Hall Z, Chiarugi D, Charidemou E, et al.Hall Z, Chiarugi D, Charidemou E, Leslie J, Scott E, Pellegrinet L, Allison M, Mocciaro G, Anstee Q, Evan G, Hoare M, Vidal-Puig A, Oakley F, Vacca M, Griffin J close, 2021, Lipid remodelling in hepatocyte proliferation and hepatocellular carcinoma, Hepatology, Vol:73, ISSN:0270-9139, Pages:1028-1044

Bianchi A, Marchetti L, Hall Z, et al.Bianchi A, Marchetti L, Hall Z, Lemos H, Vacca M, Paish H, Green K, Elliott B, Tiniakos D, Passos JF, Jurk D, Mann DA, Wilson CL close, 2021, Moderate exercise inhibits age-related inflammation, liver steatosis, senescence, and tumorigenesis., Journal of Immunology, Vol:206, ISSN:0022-1767, Pages:904-916

Hall Z, Wilson CH, Burkhart DL, et al.Hall Z, Wilson CH, Burkhart DL, Ashmore T, Evan GI, Griffin JL close, 2020, Myc linked to dysregulation of cholesterol transport and storage in non-small cell lung cancer., Journal of Lipid Research, Vol:61, ISSN:0022-2275, Pages:1390-1399

Bond NJ, Koulman A, Griffin JL, et al.Bond NJ, Koulman A, Griffin JL, Hall Z close, 2017, massPix: an R package for annotation and interpretation of mass spectrometry imaging data for lipidomics, Metabolomics, Vol:13, ISSN:1573-3882

Hall Z, Chu Y, Griffin JL, 2017, Liquid extraction surface analysis mass spectrometry method for identifying the presence and severity of nonalcoholic fatty liver disease, Analytical Chemistry, Vol:89, ISSN:0003-2700, Pages:5161-5170

Hall Z, Bond NJ, Ashmore T, et al.Hall Z, Bond NJ, Ashmore T, Sanders F, Ament Z, Wang X, Murray AJ, Bellafante E, Virtue S, Vidal-Puig A, Allison M, Davies SE, Koulman A, Vacca M, Griffin JL close, 2017, Lipid zonation and phospholipid remodeling in nonalcoholic fatty liver disease, Hepatology, Vol:65, ISSN:0270-9139, Pages:1165-1180

Hall Z, Ament Z, Wilson CH, et al.Hall Z, Ament Z, Wilson CH, Burkhart DL, Ashmore T, Koulman A, Littlewood T, Evan GI, Griffin JL close, 2016, Myc expression drives aberrant lipid metabolism in lung cancer, Cancer Research, Vol:76, ISSN:1538-7445, Pages:4608-4618

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