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• Journal article
  NUTT DJ, GLUE P, 1989,

  CLINICAL-PHARMACOLOGY OF ANXIOLYTICS AND ANTIDEPRESSANTS - A PSYCHOPHARMACOLOGICAL PERSPECTIVE

  , PHARMACOLOGY & THERAPEUTICS, Vol: 44, Pages: 309-334, ISSN: 0163-7258
  • Cite
  • Citations: 57
• Journal article
  GLEITER CH, NUTT DJ, 1989,

  CHRONIC ELECTROCONVULSIVE SHOCK AND NEUROTRANSMITTER RECEPTORS - AN UPDATE

  , LIFE SCIENCES, Vol: 44, Pages: 985-1006, ISSN: 0024-3205
  • Author Web Link
  • Cite
  • Citations: 57
• Journal article
  Nutt D, Adinoff B, Linnoila M, 1989,

  Benzodiazepines in the treatment of alcoholism.

  , Recent Dev Alcohol, Vol: 7, Pages: 283-313, ISSN: 0738-422X

  This chapter comprises three sections that cover the main aspects of benzodiazepines and alcohol: (1) the basic pharmacology of benzodiazepines; (2) use of benzodiazepines in the treatment of withdrawal; and (3) the use of benzodiazepines in treating alcoholics. The basic studies suggest that a major site of action of alcohol may be the GABA/benzodiazepine receptor complex and that compensatory alterations in this complex may underly withdrawal. In the section on alcohol withdrawal, interactions between the GABA/benzodiazepine receptor complex, sympathetic nervous system, and hypothalamic-pituitary-adrenal axis are discussed. Use of benzodiazepines in the treatment of the alcohol withdrawal syndrome are reviewed, including the possibility that the benzodiazepines may prevent withdrawal-induced "kindling." Lastly, we review indications for, and efficacy of, benzodiazepines in long-term treatment of patients with alcoholism. Benzodiazepines are not indicated for the treatment of alcoholism. Furthermore, they have very few indications in alcoholics and their dependency-producing potency has to be appreciated when they are used in patients with alcoholism.

  • Abstract
  • Author Web Link
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• Journal article
  GLEITER CH, COSTELLO MJ, NUTT DJ, 1989,

  EFFECT OF SINGLE AND REPEATED ELECTROCONVULSIVE SHOCK ON BODY-TEMPERATURE IN MICE

  , CONVULSIVE THERAPY, Vol: 5, Pages: 152-156, ISSN: 0749-8055
  • Author Web Link
  • Cite
  • Citations: 6
• Journal article
  NUTT DJ, GLEITER CH, GLUE P, 1989,

  NEURO-PHARMACOLOGICAL ASPECTS OF ECT - IN SEARCH OF THE PRIMARY MECHANISM OF ACTION

  , CONVULSIVE THERAPY, Vol: 5, Pages: 250-260, ISSN: 0749-8055
  • Author Web Link
  • Cite
  • Citations: 14
• Journal article
  BONE GHA, MAJCHROWICZ E, MARTIN PR, LINNOILA M, NUTT DJet al., 1989,

  A COMPARISON OF CALCIUM-ANTAGONISTS AND DIAZEPAM IN REDUCING ETHANOL WITHDRAWAL TREMORS

  , PSYCHOPHARMACOLOGY, Vol: 99, Pages: 386-388, ISSN: 0033-3158
  • Cite
  • Citations: 40
• Journal article
  LISTER RG, DURCAN MJ, NUTT DJ, LINNOILA Met al., 1989,

  ATTENUATION OF ETHANOL INTOXICATION BY ALPHA-2 ADRENOCEPTOR ANTAGONISTS

  , LIFE SCIENCES, Vol: 44, Pages: 111-119, ISSN: 0024-3205
  • Cite
  • Citations: 26
• Journal article
  GLUE P, BACHER JD, NUTT DJ, 1988,

  A TECHNIQUE FOR CHRONIC CATHETERIZATION OF THE CISTERNA MAGNA IN RABBITS

  , LABORATORY ANIMAL SCIENCE, Vol: 38, Pages: 740-742, ISSN: 0023-6764
  • Author Web Link
  • Cite
  • Citations: 2
• Journal article
  NUTT DJ, LINNOILA M, 1988,

  NEURORECEPTOR SCIENCE - A CLARIFICATION OF TERMS

  , JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY, Vol: 8, Pages: 387-389, ISSN: 0271-0749
  • Author Web Link
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  • Citations: 3
• Journal article
  NUTT DJ, LISTER RG, 1988,

  ANTAGONIZING THE ANTICONVULSANT EFFECT OF ETHANOL USING DRUGS ACTING AT THE BENZODIAZEPINE GABA RECEPTOR COMPLEX

  , PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, Vol: 31, Pages: 751-755, ISSN: 0091-3057
  • Cite
  • Citations: 10

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