TY - JOUR AB - Objectives: Microindentation hasthe potential to measuretheelasticity(stiffness)of individualpatients’bone. Bone elasticity plays a crucial role in the press-fit stability of orthopaedic implants.Arming surgeons with accuratebone elasticityinformation may reduce surgical complicationsincluding peri-prosthetic fractures. The question we address with this systematicreview is whether microindentation can accurately measure cortical bone stiffness.Methods: A systematic review of all English language articles using a keyword search was undertaken in Medline, Embase, PubMed, Scopus and Cochrane databases. Studies thatonly used nanoindentation, cancellous boneoranimal tissue were excluded.Results: 1094abstracts were retrieved and 32papers were included in the analysis, 20 of which used reference point indentation and 12of which used traditional depth sensing indentation.There are a number of factors thatmust be taken into account when using microindentation such as tip size, depth and method of analysis.Only two studies validated microindentation againsttraditional mechanical testing techniques. Bothstudies used reference point indentation(RPI) with one showing that RPI parameters correlate well with mechanical testing, butanother suggestedthatthey do not. Conclusion: Microindentation has been used in various studies to assess bone elasticity but only two studies with conflicting results compared microindentation to traditional mechanical testing techniques. Further research,includingmore studies comparingmicroindentationto other mechanical testing methodsare needed,before microindentation can be reliably used to calculate cortical bone stiffness. AU - Arnold,M AU - Zhao,S AU - Ma,S AU - Giuliani,F AU - Hansen,U AU - Cobb,JP AU - Abel,RL AU - Boughton,OR DO - 10.1302/2046-3758.69.BJR-2016-0317.R2 EP - 549 PY - 2017/// SN - 2046-3758 SP - 542 TI - Microindentation: a tool for measuring cortical bone stiffness? A systematic review T2 - Bone & Joint Research UR - http://dx.doi.org/10.1302/2046-3758.69.BJR-2016-0317.R2 UR - http://hdl.handle.net/10044/1/49906 VL - 6 ER -