TY - JOUR AB - Atrial and ventricular fibrillation are complex arrhythmias, and their underlying mechanisms remain widely debated and incompletely understood. This is partly because the electrical signals recorded during myocardial fibrillation are themselves complex and difficult to interpret with simple analytical tools. There are currently a number of analytical approaches to handle fibrillation data. Some of these techniques focus on mapping putative drivers of myocardial fibrillation, such as dominant frequency, organizational index, Shannon entropy and phase mapping. Other techniques focus on mapping the underlying myocardial substrate sustaining fibrillation, such as voltage mapping and complex fractionated electrogram mapping. In this review, we discuss these techniques, their application and their limitations, with reference to our experimental and clinical data. We also describe novel tools including a new algorithm to map microreentrant circuits sustaining fibrillation. AU - Handa,BS AU - Roney,CH AU - Houston,C AU - Qureshi,N AU - Li,X AU - Pitcher,DS AU - Chowdhury,RA AU - Lim,PB AU - Dupont,E AU - Niederer,S AU - Cantwell,C AU - Peters,NS AU - Ng,FS DO - 10.1016/j.compbiomed.2018.07.008 EP - 326 PY - 2018/// SN - 0010-4825 SP - 315 TI - Analytical approaches for myocardial fibrillation signals T2 - Computers in Biology and Medicine UR - http://dx.doi.org/10.1016/j.compbiomed.2018.07.008 UR - https://www.imperial.ac.uk/people/balvinder.handa05 UR - https://www.sciencedirect.com/science/article/pii/S0010482518301999?via%3Dihub UR - http://hdl.handle.net/10044/1/62278 VL - 102 ER -