TY - JOUR AB - Understanding how to moderate and improve catalytic activity is critical to improving degradable polymer production. Here, di- and mono-zinc catalysts, coordinated by bis(imino)diphenylamido ligands, show remarkable activities and allow determination of the factors controlling performance. In most cases, the di-zinc catalysts significantly out-perform the mono-zinc analogues. Further, for the best di-zinc catalyst, the ligand conformation controls activity: the catalyst with ‘folded’ ligand conformations show TOF values up to 60,000 h-1 (0.1 mol% loading, 298 K, [LA] = 1 M), whilst that with a ‘planar’ conformation is much slower, under similar conditions (TOF = 30 h-1). Di-zinc catalysts also perform very well under immortal conditions, showing improved control, and are able to tolerate loadings as low as 0.002 mol% whilst conserving high activity (TOF = 12,500 h-1). AU - Thevenon,A AU - Romain,C AU - Bennington,M AU - White,A AU - Davidson,H AU - Brooker,S AU - Williams,CK DO - 10.1002/anie.201602930 EP - 8685 PY - 2016/// SN - 1433-7851 SP - 8680 TI - Di-zinc Lactide Polymerization Catalysts: Hyper-Activity by Control of Ligand Conformation and Metallic Cooperativity T2 - Angewandte Chemie - International Edition UR - http://dx.doi.org/10.1002/anie.201602930 UR - http://hdl.handle.net/10044/1/32156 VL - 55 ER -