TY - JOUR AB - This paper investigates the scaling-up of cyanobacterial biomass cultivation and biohydrogen production from laboratory to industrial scale. Two main aspects are investigated and presented, which to the best of our knowledge have never been addressed, namely the construction of an accurate dynamic model to simulate cyanobacterial photo-heterotrophic growth and biohydrogen production and the prediction of the maximum biomass and hydrogen production in different scales of photobioreactors. To achieve the current goals, experimental data obtained from a laboratory experimental setup are fitted by a dynamic model. Based on the current model, two key original findings are made in this work. First, it is found that selecting low-chlorophyll mutants is an efficient way to increase both biomass concentration and hydrogen production particularly in a large scale photobioreactor. Second, the current work proposes that the width of industrial scale photobioreactors should not exceed 0.20 m for biomass cultivation and 0.05 m for biohydrogen production, as severe light attenuation can be induced in the reactor beyond this threshold. AU - Zhang,D AU - Dechatiwongse,P AU - del,Rio-Chanona EA AU - Maitland,GC AU - Hellgardt,K AU - Vassiliadis,VS DO - 10.1002/bit.25661 EP - 2438 PY - 2015/// SN - 1097-0290 SP - 2429 TI - Dynamic modelling of high biomass density cultivation and biohydrogen production in different scales of flat plate photobioreactors T2 - Biotechnology and Bioengineering UR - http://dx.doi.org/10.1002/bit.25661 UR - http://hdl.handle.net/10044/1/41966 VL - 112 ER -