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  • Journal article
    Cold JW, Kallis C, Doyle M, Shaw J, Ullrich Set al., 2018,

    Shifts in positive and negative psychotic symptoms and anger: effects on violence

    , PSYCHOLOGICAL MEDICINE, Vol: 48, Pages: 2428-2438, ISSN: 0033-2917
  • Journal article
    Coid JW, Hu J, Kallis C, Ping Y, Zhang J, Hu Y, Zhang T, Gonzalez R, Ullrich S, Jones PB, Kirkbride JBet al., 2018,

    Urban Birth, Urban Living, and Work Migrancy: Differential Effects on Psychotic Experiences Among Young Chinese Men

    , SCHIZOPHRENIA BULLETIN, Vol: 44, Pages: 1123-1132, ISSN: 0586-7614
  • Journal article
    Coid J, Hu J, Kallis C, Ping Y, Zhang J, Hu Y, Bui L, Ullrich S, Bebbington Pet al., 2017,

    A cross-national comparison of violence among young men in China and the UK: psychiatric and cultural explanations

    , SOCIAL PSYCHIATRY AND PSYCHIATRIC EPIDEMIOLOGY, Vol: 52, Pages: 1267-1279, ISSN: 0933-7954
  • Journal article
    Mallik S, Kallis C, Lunn MPT, Smith AGet al., 2017,

    Gangliosides for the treatment of diabetic peripheral neuropathy

    , Cochrane Database of Systematic Reviews, Vol: 2017

    This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess the benefits and harms of treatment with gangliosides in diabetic peripheral neuropathy.
  • Journal article
    Eberhardt C, Thillai M, Parker R, Siddiqui N, Potiphar L, Goldin R, Timms JF, Wells AU, Kon OM, Wickremasinghe M, Mitchell D, Weeks ME, Lalvani Aet al., 2017,

    Proteomic analysis of Kveim reagent identifies targets of cellular immunity in sarcoidosis

    , PLOS ONE, Vol: 12, ISSN: 1932-6203

    Background:Kveim-reagent (Kv) skin testing was a historical method of diagnosing sarcoidosis. Intradermal injection of treated sarcoidosis spleen tissue resulted in a granuloma response at injection site by 4–6 weeks. Previous work indicates proteins as the possible trigger of this reaction. We aimed to identify Kv-specific proteins and characterise the ex vivo response of Peripheral Blood Mononuclear Cells (PBMCs) from sarcoidosis, tuberculosis and healthy control patients when stimulated with both Kv and selected Kv-specific proteins.Methods:Kv extracts were separated by 1D-SDS-PAGE and 2D-DIGE and then underwent mass spectrometric analysis for protein identification. Sarcoidosis and control PBMCs were first stimulated with Kv and then with three selected recombinant protein candidates which were identified from the proteomic analysis. PBMC secreted cytokines were subsequently measured by Multiplex Cytokine Assay.Results:We observed significantly increased IFN-γ and TNF-α secretion from Kv-stimulated PBMCs of sarcoidosis patients vs. PBMCs from healthy volunteers (IFN-γ: 207.2 pg/mL vs. 3.86 pg/mL, p = 0.0018; TNF-α: 2375 pg/mL vs. 42.82 pg/mL, p = 0.0003). Through proteomic approaches we then identified 74 sarcoidosis tissue-specific proteins. Of these, 3 proteins (vimentin, tubulin and alpha-actinin-4) were identified using both 1D-SDS-PAGE and 2D-DIGE. Data are available via ProteomeXchange with identifier PXD005150. Increased cytokine secretion was subsequently observed with vimentin stimulation of sarcoidosis PBMCs vs. tuberculosis PBMCs (IFN-γ: 396.6 pg/mL vs 0.1 pg/mL, p = 0.0009; TNF-α: 1139 pg/mL vs 0.1 pg/mL, p<0.0001). This finding was also observed in vimentin stimulation of sarcoidosis PBMCs compared to PBMCs from healthy controls (IFN-γ: 396.6 pg/mL vs. 0.1 pg/mL, p = 0.014; TNF-α: 1139 pg/mL vs 42.29 pg/mL, p = 0.027). No difference was found in cytokine secretion between sarcoidosis and contr
  • Journal article
    Davoren M, Kallis C, Gonzalez RA, Freestone M, Coid JWet al., 2017,

    Anxiety disorders and intimate partner violence: can the association be explained by coexisting conditions or borderline personality traits?

    , JOURNAL OF FORENSIC PSYCHIATRY & PSYCHOLOGY, Vol: 28, Pages: 639-658, ISSN: 1478-9949
  • Journal article
    Wood JL, Kallis C, Coid JW, 2017,

    Differentiating Gang Members, Gang Affiliates, and Violent Men on Their Psychiatric Morbidity and Traumatic Experiences

    , PSYCHIATRY-INTERPERSONAL AND BIOLOGICAL PROCESSES, Vol: 80, Pages: 221-235, ISSN: 0033-2747
  • Journal article
    Cold JW, Bhui K, MacManus D, Kallis C, Bebbington P, Ullrich Set al., 2016,

    Extremism, religion and psychiatric morbidity in a population-based sample of young men

    , BRITISH JOURNAL OF PSYCHIATRY, Vol: 209, Pages: 491-497, ISSN: 0007-1250
  • Journal article
    Coid JW, Ullrich S, Kallis C, Freestone M, Gonzalez R, Bui L, Igoumenou A, Constantinou A, Fenton N, Marsh W, Yang M, DeStavola B, Hu J, Shaw J, Doyle M, Archer-Power L, Davoren M, Osumili B, McCrone P, Barrett K, Hindle D, Bebbington Pet al., 2016,

    Improving risk management for violence in mental health services: a multimethods approach

    , Programme Grants for Applied Research, Vol: 4, Pages: 1-408, ISSN: 2050-4322

    <jats:sec id="abs1-1"><jats:title>Background</jats:title><jats:p>Mental health professionals increasingly carry out risk assessments to prevent future violence by their patients. However, there are problems with accuracy and these assessments do not always translate into successful risk management.</jats:p></jats:sec><jats:sec id="abs1-2"><jats:title>Objectives</jats:title><jats:p>Our aim was to improve the accuracy of assessment and identify risk factors that are causal to be targeted by clinicians to ensure good risk management. Our objectives were to investigate key risks at the population level, construct new static and dynamic instruments, test validity and construct new models of risk management using Bayesian networks.</jats:p></jats:sec><jats:sec id="abs1-3"><jats:title>Methods and results</jats:title><jats:p>We utilised existing data sets from two national and commissioned a survey to identify risk factors at the population level. We confirmed that certain mental health factors previously thought to convey risk were important in future assessments and excluded others from subsequent parts of the study. Using a first-episode psychosis cohort, we constructed a risk assessment instrument for men and women and showed important sex differences in pathways to violence. We included a 1-year follow-up of patients discharged from medium secure services and validated a previously developed risk assessment guide, the Medium Security Recidivism Assessment Guide (MSRAG). We found that it is essential to combine ratings from static instruments such as the MSRAG with dynamic risk factors. Static levels of risk have important modifying effects on dynamic risk factors for their effects on violence and we further demonstrated this using a sample of released prisoners to construct risk assessment instruments for violence, robbery, drugs and acquisitive
  • Journal article
    Gonzalez RA, Igoumenou A, Kallis C, Coid JWet al., 2016,

    Borderline personality disorder and violence in the UK population: categorical and dimensional trait assessment

    , BMC Psychiatry, Vol: 16, ISSN: 1471-244X

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