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Journal articleSpivey AC, Fekner T, Spey SE, 2000,
Axially chiral analogues of 4-(dimethylamino)pyridine: Novel catalysts for nonenzymatic enantioselective acylations
, JOURNAL OF ORGANIC CHEMISTRY, Vol: 65, Pages: 3154-3159, ISSN: 0022-3263- Author Web Link
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- Citations: 167
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Journal articleSpivey AC, Maddaford A, Redgrave AJ, 2000,
Asymmetric catalysis of acyl transfer by lewis acids and nucleophiles. A review
, Organic Preparations and Procedures International, Vol: 32, Pages: 331-365, ISSN: 0030-4948- Cite
- Citations: 114
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Journal articleSpivey AC, Andrews BI, 2000,
Synthetic methods part (iv) protecting groups
, Annual Reports on the Progress of Chemistry - Section B, Vol: 2000, Pages: 65-83, ISSN: 0069-3030Another excellent and comprehensive "update" review of protecting group (PG) strategies in organic synthesis has appeared this year.1 Additionally, a substantially expanded and updated 3rd edition of the classic "Protective Groups in Organic Synthesis" has been published.2 An introductory text on protecting groups has also appeared.3.
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Journal articleSpivey AC, Maddaford A, Fekner T, et al., 2000,
Synthesis of <i>C</i><sub>2</sub>-symmetric analogues of 4-(pyrrolidino)pyridine:: new chiral nucleophilic catalysts
, JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, Pages: 3460-3468, ISSN: 1472-7781- Author Web Link
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- Citations: 75
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Journal articleSpivey AC, Maddaford A, 1999,
Synthetic methods: Part (v) Protecting groups
, Annual Reports on the Progress of Chemistry - Section B, Vol: 1999, Pages: 83-95, ISSN: 0069-3030Another excellent and comprehensive 'update' review of protecting group strategies in organic synthesis has appeared this year. 1 Additionally, a useful review focusing on enzymes as 'reagents' for protecting group manipulation (mainly esters and amides) has been published. 2.
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Journal articleSpivey AC, Diaper CM, Rudge AJ, 1999,
Correction: A new germanium based linker for solid phase synthesis of aromatic compounds (Chemical Communications (1999) (835))
, Chemical Communications, ISSN: 1359-7345 -
Journal articleSpivey AC, Diaper CM, Rudge AJ, 1999,
A new germanium based linker for solid phase synthesis of aromatic compounds
, CHEMICAL COMMUNICATIONS, Pages: 835-836, ISSN: 1359-7345- Author Web Link
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- Citations: 19
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Journal articleSpivey AC, Hanson R, Scorah N, et al., 1999,
Sharpless asymmetric dihydroxylation: Effect of alkene structure on rates and selectivity - An undergraduate organic laboratory group experiment
, JOURNAL OF CHEMICAL EDUCATION, Vol: 76, Pages: 655-659, ISSN: 0021-9584- Author Web Link
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- Citations: 12
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Journal articleSpivey AC, Andrews BI, Brown AD, et al., 1999,
First asymmetric desymmetrisation of a centrosymmetric molecule: CBS reduction of a 2-pyridone [4+4]-photodimer derivative
, CHEMICAL COMMUNICATIONS, Pages: 2523-2524, ISSN: 1359-7345- Author Web Link
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- Citations: 18
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Journal articleSpivey AC, Fekner T, Spey SE, et al., 1999,
Configurationally Stable Biaryl Analogues of 4-(Dimethylamino)pyridine: A Novel Class of Chiral Nucleophilic Catalysts
, The Journal of Organic Chemistry, Vol: 64, Pages: 9430-9443-9430-9443 -
Journal articleSpivey AC, 1998,
2 Synthetic methods: Part (v) Protecting groups
, Annual Reports on the Progress of Chemistry - Section B, Vol: 94, Pages: 77-87, ISSN: 0069-3030- Cite
- Citations: 2
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Journal articleHelm BA, Sayers I, Swan J, et al., 1998,
Protein and cell engineering of components of the human immunoglobulin E receptor/effector system: applications for therapy and diagnosis.
, Technol Health Care, Vol: 6, Pages: 195-207, ISSN: 0928-7329Adaptive immune responses characterised by the synthesis of antibodies of the immunoglobulin E (IgE) isotype play an important role in type I hypersensitivity disorders and parasitic infestations, diseases which have an significant socioeconomic impact world-wide. This paper considers potential applications of recent advances in our understanding of the origin of isotype specific immune responses which emerged as a result of cell and protein engineering studies on components of the human IgE/receptor/effector system. Furthermore, the identification of the receptor binding regions in IgE as a result of the development of a stable assay system has important applications for the design of rational therapeutic interventions in allergy and asthma, the treatment of mast cell tumours, and the establishment of procedures for the selective isolation of cells expressing the high-affinity receptor for IgE for functional studies.
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Journal articleHawker CJ, Spivey AC, Leeper FJ, et al., 1998,
Biosynthesis of porphyrins and related macrocycles.: Part 48.: The rearrangement of 2<i>H</i>-pyrroles (pyrrolenines) related to the proposed spiro-intermediate for porphyrin biosynthesis
, JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, Pages: 1509-1517, ISSN: 0300-922X- Author Web Link
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- Citations: 11
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Journal articleHawker CJ, Stark WM, Spivey AC, et al., 1998,
Biosynthesis of porphyrins and related macrocycles.: Part 47.: Synthesis and chemistry of 2<i>H</i>-pyrroles (pyrrolenines) related to the proposed spiro-intermediate for porphyrin biosynthesis
, JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, Pages: 1493-1508, ISSN: 0300-922X- Author Web Link
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- Citations: 11
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Journal articleHelm BA, Sayers I, Padlan EA, et al., 1998,
Structure/function studies on IgE as a basis for the development of rational IgE antagonists
, ALLERGY, Vol: 53, Pages: 77-82, ISSN: 0105-4538- Author Web Link
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- Citations: 8
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Journal articleSpivey AC, Bissell AJ, Stammen B, 1998,
A practical synthesis of <i>N</i>-p-anisyl-<i>N</i>-methyl-amino-3-(9-anthryl)-propane:: An exciplex fluorescence 'thermometer'
, SYNTHETIC COMMUNICATIONS, Vol: 28, Pages: 623-632, ISSN: 0039-7911- Author Web Link
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- Citations: 4
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Journal articleSpivey AC, Fekner T, Adams H, 1998,
Synthesis of atropisomeric analogues of DMAP
, Tetrahedron Letters, Vol: 39, Pages: 8919 - 8922-8919 - 8922, ISSN: 0040-4039 -
Journal articleHelm BA, Spivey AC, Padlan EA, 1997,
Peptide blocking of IgE/receptor interaction: possibilities and pitfalls
, ALLERGY, Vol: 52, Pages: 1155-1169, ISSN: 0105-4538- Author Web Link
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- Citations: 33
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Journal articleSpivey AC, Capretta A, Frampton CS, et al., 1996,
Biosynthesis of porphyrins and related macrocycles .45. Determination by a novel X-ray method of the absolute configuration of the spiro lactam which inhibits uroporphyrinogen III synthase (cosynthetase)
, JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, Pages: 2091-2102, ISSN: 0300-922X- Author Web Link
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- Citations: 16
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Journal articleSpivey AC, Frampton CS, Battersby AR, 1996,
A new procedure for the reduction of alpha,beta-unsaturated pyrrolidinones to 2H-pyrroles and 1H-pyrroles based on initial activation by N-nitrosation
, JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, Pages: 2103-2110, ISSN: 0300-922X- Author Web Link
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- Citations: 7
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Journal articleFarthing CN, Baldwin JE, Russell AT, et al., 1996,
Syntheses of (S)-beta-pyrazolylalanine and (S)-quisqualic acid from a serine-derived aziridine
, TETRAHEDRON LETTERS, Vol: 37, Pages: 5225-5226, ISSN: 0040-4039- Author Web Link
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- Citations: 27
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Journal articleBaldwin JE, Farthing CN, Russell AT, et al., 1996,
Use of (S)-N-tert-butoxycarbonylaziridine-2-carboxylate derivatives for alpha-amino acid synthesis
, TETRAHEDRON LETTERS, Vol: 37, Pages: 3761-3764, ISSN: 0040-4039- Author Web Link
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- Citations: 66
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Journal articleSPIVEY AC, CAPRETTA A, FRAMPTON CS, et al., 1995,
STEREOCHEMICAL STUDIES ON THE PROPOSED SPIRO INTERMEDIATE FOR THE BIOSYNTHESIS OF THE NATURAL PORPHYRINS - DETERMINATION BY A NOVEL X-RAY-METHOD OF THE ABSOLUTE-CONFIGURATION OF THE SPIROLACTAM WHICH INHIBITS COSYNTHETASE
, JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, Pages: 1789-1790, ISSN: 0022-4936- Author Web Link
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- Citations: 5
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Journal articleBERNARDINELLI G, OPPOLZER W, SPIVEY AC, 1995,
(2RS)-4,4-DIMETHYL-2-[(1SR)-1-PHENYLETHYL]-1-PYRROLIDINOL
, ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS, Vol: 51, Pages: 529-530, ISSN: 0108-2701 -
Journal articleOPPOLZER W, SPIVEY AC, BOCHET CG, 1994,
SUPRAFACIALITY OF THERMAL N-4-ALKENYLHYDROXYLAMINE CYCLIZATIONS - SYNTHESES OF (PLUS-OR-MINUS)-ALPHA-LYCORANE AND (+)-TRIANTHINE
, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Vol: 116, Pages: 3139-3140, ISSN: 0002-7863- Author Web Link
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- Citations: 75
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Conference paperCLEVELAND ER, SMITH PD, GOTTLIEB AA, et al., 1993,
SPORTS-RELATED INJURIES AMONG ADOLESCENT FEMALE CHEERLEADERS - THE UNRECOGNIZED ATHLETES
, Publisher: SLACK INC, Pages: A779-A779, ISSN: 0009-9279 -
Journal articleBALDWIN JE, SPIVEY AC, SCHOFIELD CJ, et al., 1993,
AMINO-ACID SYNTHESIS VIA RING-OPENING OF N-SULFONYL AZIRIDINE-2-CARBOXYLATE ESTERS WITH ORGANOMETALLIC REAGENTS
, TETRAHEDRON, Vol: 49, Pages: 6309-6330, ISSN: 0040-4020- Author Web Link
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- Citations: 117
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Journal articleBALDWIN JE, SPIVEY AC, SCHOFIELD CJ, 1990,
CYCLIC SULPHAMIDATES - NEW SYNTHETIC PRECURSORS FOR BETA-FUNCTIONALIZED ALPHA-AMINO-ACIDS
, TETRAHEDRON-ASYMMETRY, Vol: 1, Pages: 881-884, ISSN: 0957-4166- Author Web Link
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- Citations: 84
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Journal articleBALDWIN JE, ADLINGTON RM, ONEIL IA, et al., 1989,
THE RING-OPENING OF AZIRIDINE-2-CARBOXYLATE ESTERS WITH ORGANOMETALLIC REAGENTS
, JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, Pages: 1852-1854, ISSN: 0022-4936- Author Web Link
- Cite
- Citations: 97
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Contact details
Email: a.c.spivey@imperial.ac.uk
Skype: alan.spivey
Tel & Fax: +44 (0)20 75945841
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